AMMONIUM SULFATE CAS N°: 7783-20-2
AMMONIUM SULFATE CAS N°: 7783-20-2
AMMONIUM SULFATE CAS N°: 7783-20-2
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OECD SIDS<br />
<strong>AMMONIUM</strong> <strong>SULFATE</strong><br />
5. TOXICITY ID: <strong>7783</strong>-<strong>20</strong>-2<br />
DATE: 18.04.<strong>20</strong>06<br />
sulfate aerosol, or 70 µg/m3 sulfuric acid during a 40-min<br />
exposure period composed of 30 min at rest and 10 min of<br />
light exercise.70 µg/m3 of ammonium sulfate or sulfuric<br />
acid. The MMAD of the aerosol was 0.6 µm. Oral ammonia<br />
levels and pulmonary function parameters (forced expiratory<br />
volume in one second, forced vital capacity, and total<br />
respiratory resistance) were measured before and after each<br />
exposure. None of the functional parameters in either group<br />
showed significant changes. However, total respiratory<br />
resistance changes from baseline after sulfuric acid<br />
exposure were significantly higher (+16%) in the asthmatic<br />
subjects, compared with the healthy subjects (-6%).<br />
Reliability:<br />
(2) valid with restrictions<br />
valid with restrictions<br />
Flag:<br />
Critical study for SIDS endpoint<br />
10-APR-<strong>20</strong>06 (184)<br />
5.11 Additional Remarks<br />
Type:<br />
Reliability:<br />
adsorption<br />
(2) valid with restrictions<br />
reliable review<br />
26-AUG-<strong>20</strong>05 (11)<br />
Type:<br />
Reliability:<br />
adsorption<br />
(2) valid with restrictions<br />
reliable review<br />
10-APR-<strong>20</strong>06 (12)<br />
Type:<br />
Remark:<br />
Reliability:<br />
other: Review<br />
The health effect of sulfur dioxides and particulate matter<br />
in ambient air is reviewed.<br />
(4) not assignable<br />
10-APR-<strong>20</strong>06 (185)<br />
Type:<br />
Remark:<br />
218<br />
other: occupational exposure<br />
Exposure of workers to ammonium sulfate may occur during<br />
production, transport and processing, or through the<br />
professional use of ammonium sulfate containing products. Main<br />
exposure routes are the respiratory route (inhalation of<br />
aqueous aerosols or dust), or dermal contact with the solid.<br />
Exposure of workers to dust during production and storage,<br />
loading and unloading of trucks was measured. Eight<br />
measurements of respirable dust (including fine dust fraction)<br />
were carried out within 8 h (personal air samplers and<br />
sampling from the working room), but no analysis for ammonium<br />
sulfate performed, assumed as 100 %.<br />
Results: all measurements showed concentrations close to the<br />
detection limit. Personal air samplings for respirable dust<br />
showed values < 0.354 - 0.360 mg/m3 (four samples) and for<br />
fine dust < 0.442 - 0.455 mg/m3 (four samples).<br />
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