AMMONIUM SULFATE CAS N°: 7783-20-2

OECD SIDS
AMMONIUM SULFATE
5. TOXICITY ID: 7783-20-2
DATE: 18.04.2006
fixed dose level, the chemical was regarded as having an
LD50 near that dose level, and the approximate LD50 of the
chemical was indicated as ca. 20, 200 or 2000 mg/kg bw.
Year of study: not reported.
Reliability: (2) valid with restrictions
limited documentation, open application, no further
information on purity
Flag:
Critical study for SIDS endpoint
24-AUG-2005 (113)
5.1.4 Acute Toxicity, other Routes
Type:
LD50
Species:
mouse
Strain:
no data
Sex:
male/female
Vehicle:
other: the test substance was applied as 8% aqueous solution
Doses:
no data
Route of admin.: i.p.
Value:
900 mg/kg bw
Method:
other: see Test Condition
Year: 1969
GLP:
no
Test substance: other TS: as prescribed by 1.1 - 1.4, "chemically pure"
Result:
The LD50 was determined to be 900 mg/kg bw (95% confidence
limits: 608-1332).
Clinical signs observed were: dyspnoea, tremor,
palpitations, cramps, and prostration at dose levels near to
or exceeding the LD50.
At necropsy, no pathological findings were noted.
Test condition: According to "Description of methods used in BASF acute
toxicity and skin/eye irritation studies before pertinent
OECD/EU test guidelines were in place" (BASF AG, 2002).
The test substance was applied as 8% aqueous solution to
groups of mice as single intraperitoneal injection at
various dose levels. The LD50 was calculated according to
the method described by Litchfield-Wilcoxon.
Post exposure period: 7d
Reliability: (2) valid with restrictions
limited documentation, post exposure observation period only 7
days
18-NOV-2003 (111)
Type:
LD50
Species:
mouse
Route of admin.: i.p.
Value:
= 610 mg/kg bw
Method:
GLP:
Test substance:
other: no data
no data
other TS: no data
Reliability: (4) not assignable
secondary citation
09-MAR-2003 (125)
UNEP PUBLICATIONS 159