Arbeit komplett 12.07.2003 komplett Annahmeste - ArchiMeD

10 Experimenteller, chemisch-präparativer Teil 160
Ausbeute: 3,71 g (17,6 mmol; 84%) Lit. 176 : 88%
Schmelzpunkt: 190-192°C (Ethanol) Lit. 174 : 190-191°C
1 H-NMR δ [ppm]:
(300 MHz) Aceton-d6
6.86 (d, 4 J=1.51, 1H, CH, 3-H); 7.03 (ddd, 3 J=7.91, 3 J=7.91,
4 J=1.13, 1H, CH, 6-H); 7.12 (ddd, 3 J=7.16, 3 J=7.91,
4 J=1.13, 1H, CH, 5-H); 7.23 (dd, 3 J=9.04, 3 J=8.67, 2H,
2xCH, 3'-H, 5'-H); 7.41 (dd, 3 J=7.91, 4 J=0.75, 1H, CH, 7-H);
7.57 (d, 3 J=7.91, 1H, CH, 4-H); 7.89 (dd, 3 J=5.28, 3 J(H,
F)=7.91, 1H, 2xCH, 2'-H, 6'-H); 10.67 (s, 1H, NH)
EI-MS (70 eV); m/z (%) 211.3 (_, 100.00), 183.1 (33.40), 105.5 (20.49), 90.4
(15.34), 89.1 (14.63)
Elementaranalyse (%): Ber.: C: 79.60 H: 4.77 N: 6.63 F: 8.99
Gef.: C: 79.49 H: 4.78 N: 6.68 F: 9.06
IR (KBr); ö [cm -1 ] 3347 (s) 3301 (s) 3058 (w) 3029 (w) 2948 (m)
2901 (w) 2838 (w) 1679 (s) 1610 (s) 1579 (s)
1537 (m) 1499 (m) 1456 (s) 1435 (s) 1409 (m)
1374 (m) 1347 (m) 1323 (m) 1308 (m) 1298 (s)
1282 (s) 1261 (s) 1238 (s) 1195 (s) 1178 (s)
1149 (m) 1114 (m) 1082 (m) 1044 (m) 1031 (m)
999 (m) 978 (m) 959 (m) 946 (w) 849 (m)
834 (m) 811 (m) 793 (m) 766 (w) 750 (m)
722 (m)
10.2.6.6 2-(4-Fluorophenyl)-1H-indol (29)
Summenformel: C15H12FN
Molekulargewicht: 225,26
6
5
7
4
7a
1
N
3
2
CH3
176 Joshi, K. C.; Pathak, V. N.; Singh, R. P.; Monatsh. Chem., 111, 1343-1350, (1980)
3a
1'
6'
2'
5'
3'
4'
F