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47 2 MODERN TIMES.<br />

possible to trace out carefully the course of the nerve-fibres<br />

in the brain and spinal cord, to determine their distribution<br />

in these organs, and to observe the minuter structure of the<br />

grey substance and the different forms of its cells; while at<br />

the same time by experiments on living animals, which<br />

consisted of effecting a local destruction of, and consequentabolition<br />

of vital functions in, certain parts of the central<br />

nervous system, men sought to determine the normal functions<br />

of such parts. A comparison was made between the<br />

results thus obtained and observations made at the bedside<br />

or in the post-mortem room.<br />

The physiology of the sense organs was also the subject<br />

of assiduous study. The origin of the visual act, the perception<br />

of colours, the importance of that part of the eye<br />

which is sensitive to light, the mechanism of accommodation,<br />

the action of the refractive media, intraocular appearances,<br />

binocular vision, the subject of the horopter, etc., were all.<br />

submitted to thorough examination and rendered intelligible<br />

by the accumulation of numerous facts. In the same<br />

way the senses of hearing, smell, and taste, and tactual<br />

and general sensation were studied individually and made<br />

subjects of scientific knowledge.<br />

Physiological research however has not only succeeded<br />

in rendering an almost complete account of the problem of<br />

the functions and laws of the human organism in health:<br />

it has, in addition, brought forward a number of observations<br />

which have prepared and smoothed the way for an<br />

explanation of phenomena manifested by the body in<br />

disease.<br />

DIAGNOSIS, PATHOLOGICAL ANATOMY AND<br />

EXPERIMENTAL PATHOLOGY, NOSOLOGY<br />

AND MATERIA MEDICA.<br />

PATHOLOGY, the science which deals with disease, has<br />

been marked throughout by stages of development similar;<br />

to those which have characterized physiology. After men

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