Bulletin 2011/27 - European Patent Office
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(C07C) I.1(2)<br />

AL BA RS<br />

(86) JP 2009/064542 20.08.2009<br />

(87) WO 2010/021351 2010/08 25.02.2010<br />

(30) 22.08.2008 JP 2008213843<br />

(54) • CYCLOALKYLAMINDERIVAT<br />

• CYCLOALKYLAMINE DERIVATIVE<br />

• DÉRIVÉ DE CYCLOALKYLAMINE<br />

(71) Daiichi Sankyo Company, Limited, 3-5-1,<br />

Nihonbashi Honcho, Chuo-ku Tokyo 103-<br />

8426, JP<br />

(72) MARUMOTO, Shinji, Shinagawa-ku Tokyo<br />

140-8710, JP<br />

NISHIMATA, Toyoki, Shinagawa-ku Tokyo<br />

140-8710, JP<br />

EBISAWA, Masayuki, Shinagawa-ku Tokyo<br />

140-8710, JP<br />

ASOH, Yusuke, Shinagawa-ku Tokyo 140-<br />

8710, JP<br />

FUKUSHIMA, Yasuo, Shinagawa-ku Tokyo<br />

140-8710, JP<br />

KATO, Mikio, Shinagawa-ku Tokyo 140-<br />

8710, JP<br />

(74) Fairbairn, Angus Chisholm, Marks & Clerk<br />

LLP 90 Long Acre, London WC2E 9RA, GB<br />

C07C 237/36 → (51) C07C 229/46<br />

C07C 323/52 → (51) C07C 229/46<br />

C07D 207/<strong>27</strong> → (51) A61K 31/40<br />

C07D 207/452→ (51) A61K 31/40<br />

(51) C07D 209/22 (11) 2 341 045 A1<br />

A61K 31/40<br />

(25) En (26) En<br />

(21) 10180825.1 (22) 31.03.1995<br />

(84) AT BE CH DE DK ES FR GB GR IE IT LI LU NL<br />

PT SE<br />

(30) 01.04.1994 US 221916<br />

(54) • [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-<br />

(phenylmethyl)-11H-indol-4-yl]oxy]Essigsäure<br />

(acyloxy)alkyl oder ((alkoxycarbonyl)<br />

oxy)alkyl Ester als SPLA2 Inhibitor<br />

• [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-<br />

(phenylmethyl)-11H-indol-4-yl]oxy]acetic<br />

acid (acyloxy)alkyl or ((alkoxycarbonyl)<br />

oxy)alkyl ester as SPLA2 inhibitor<br />

• Ester (acyloxy)alkyle ou ((alkoxycarbonyl)<br />

oxy)alkyle de l'acide acétique de [[3-(2amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-11H-indol-4-yl]oxy]<br />

comme inhibiteur<br />

de SPLA2<br />

(71) Eli Lilly and Company, Lilly Corporate Center,<br />

Indianapolis, IN 46285, US<br />

(72) Bach, Nicholas James, Indianapolis, IN<br />

46217, US<br />

Draheim, Susan Elizabeth, Indianapolis, IN<br />

46220, US<br />

Dillard, Robert Delane, Zionsville, IN 46077,<br />

US<br />

(74) Harrison Goddard Foote, Belgrave Hall Belgrave<br />

Street, Leeds LS2 8DD, GB<br />

(62) 08001265.1 / 1 950 200<br />

00203897.4 / 1 081 135<br />

95302166.4 / 0 675 110<br />

(51) C07D 211/58 (11) 2 341 046 A2<br />

C07D 491/22 A61P 35/00<br />

A61K 31/4375<br />

(25) En (26) En<br />

(21) 10191501.5 (22) 17.11.2010<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO RS SE SI SK SM TR<br />

BA ME<br />

(30) 18.11.2009 IN MU26652009<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(54) • Verfahren zur Herstellung von 7-Ethyl-10-<br />

[4-(1-Piperidino)-1-Piperidino]-Carbonyloxy-Camptothecin-Hydrochlorid-Trihydrat<br />

• Process for the preparation of 7-ethyl-10-<br />

[4-(1-piperidino)-1-piperidino] carbonyloxy-camptothecin<br />

hydrochloride trihydrate<br />

• Procédé pour la préparation d'hydrochlorure<br />

de 7-éthyl-10-[4-(1-pipéridino)-1pipéridino]<br />

carbonyloxy-camptothécine trihydrate<br />

(71) CADILA HEALTHCARE LIMITED, Zydus<br />

Tower, Satellite Cross Roads, Ahmedebad<br />

380 015, Gujarat, IN<br />

(72) Charan, Ganpat Dan Shimbhu, 380 015<br />

Ahmedabad Gujarat, IN<br />

Singh, Kumar Kamlesh Laxmi, 380 015<br />

Ahmedabad Gujarat, IN<br />

Tanpure, Arun Ankush, 380 015 Ahmedabad<br />

Gujarat, IN<br />

(74) Bassil, Nicholas Charles, et al, Kilburn &<br />

Strode LLP 20 Red Lion Street, London<br />

WC1R 4PJ, GB<br />

(51) C07D 231/12 (11) 2 341 047 A1<br />

A61K 31/415 A61K 31/421<br />

A61K 31/426 A61K 31/4439<br />

A61P 25/04 A61P 29/02<br />

C07D 263/32 C07D <strong>27</strong>7/24<br />

C07D 401/04<br />

(25) Ja (26) En<br />

(21) 09823687.0 (22) 30.10.2009<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) JP 2009/068644 30.10.2009<br />

(87) WO 2010/050577 2010/18 06.05.2010<br />

(30) 31.10.2008 JP 2008281258<br />

29.07.2009 JP 2009176619<br />

(54) • CYCLOHEXANDERIVAT UND PHARMA-<br />

ZEUTISCHE ANWENDUNG DAVON<br />

• CYCLOHEXANE DERIVATIVE AND PHAR-<br />

MACEUTICAL USE THEREOF<br />

• DÉRIVÉ DU CYCLOHEXANE ET SON UTI-<br />

LISATION PHARMACEUTIQUE<br />

(71) Toray Industries, Inc., 1-1, Nihonbashi-<br />

Muromachi 2-chome Chuo-ku, Tokyo, 103-<br />

8666, JP<br />

(72) MORITA, Yasuhiro, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

ISEKI, Katsuhiko, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

SUGAWARA, Yuji, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

TSUTSUI, Hideyuki, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

IWANO, Shunsuke, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

IZUMIMOTO, Naoki, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

ARAI, Tadamasa, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

NODA, Hidetoshi, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

YOSHIDA, Chihiro, Kamakura-shi Kanagawa<br />

248-8555, JP<br />

(74) Kador & Partner, Corneliusstrasse 15, 80469<br />

München, DE<br />

C07D 235/04 → (51) C07K 1/22<br />

C07D 257/04 → (51) C07C 229/46<br />

C07D 263/32 → (51) C07D 231/12<br />

(51) C07D <strong>27</strong>7/22 (11) 2 341 048 A1<br />

A61K 31/426 A61P 3/10<br />

A61P 9/12 A61P 9/14<br />

169<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>27</strong>/<strong>2011</strong>) 06.07.<strong>2011</strong><br />

A61P 9/10 A61P <strong>27</strong>/12<br />

A61P 25/02 A61P 19/02<br />

A61Q 11/00<br />

(25) Zh (26) En<br />

(21) 09813969.4 (22) 15.09.2009<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) CN 2009/001036 15.09.2009<br />

(87) WO 2010/031248 2010/12 25.03.2010<br />

(30) 22.09.2008 CN 200810211657<br />

(54) • THIAZOLIUMSALZVERBINDUNG UND<br />

VERWENDUNG ZUR BEHANDLUNG VON<br />

PROTEINALTERUNG<br />

• THIAZOLIUM SALT COMPOUND AND THE<br />

USE OF TREATING THE PROTEIN AGING<br />

DISEASE<br />

• COMPOSÉ DE SEL DE THIAZOLIUM ET<br />

SON UTILISATION POUR LE TRAITEMENT<br />

DE LA MALADIE DE VIEILLISSEMENT DES<br />

PROTÉINES<br />

(71) Beijing Molecule Science and Technology<br />

Co., Ltd., Apt. 301, Attached Building of<br />

Zizhu Building No. 44, Hongliannancun<br />

Haidian District, Beijing 100088, CN<br />

(72) LI, Song, Beijing 100850, CN<br />

ZHONG, Wu, Beijing 100850, CN<br />

WANG, Lili, Beijing 100850, CN<br />

ZHENG, Zhibing, Beijing 100850, CN<br />

CUI, Hao, Beijing 100850, CN<br />

XIAO, Junhai, Beijing 100850, CN<br />

CHENG, Gang, Beijing 100850, CN<br />

XIE, Yunde, Beijing 100850, CN<br />

ZHANG, Bing, Beijing 100850, CN<br />

(74) Prüfer & Partner GbR <strong>European</strong> <strong>Patent</strong><br />

Attorneys, Sohnckestraße 12, 81479<br />

München, DE<br />

C07D <strong>27</strong>7/24 → (51) C07D 231/12<br />

(51) C07D 285/10 (11) 2 341 049 A1<br />

A61K 31/433 A61P 3/10<br />

C07D 417/06<br />

(25) En (26) En<br />

(21) 11156123.9 (22) 02.04.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT RO SE SI SK<br />

TR<br />

(<strong>27</strong>) 02.04.2003 EP 03720412<br />

(30) 03.04.2002 US 369930 P<br />

03.04.2002 US 369779 P<br />

(54) • 5-substituierte 1,1-dioxo-[1,2,5]Thiazolidin-3-Onderivate<br />

als PTPASE 1B Hemmer<br />

• 5-substituted 1,1-dioxo-[1,2,5]thiazolidine-<br />

3-one derivatives as PTPASE 1B inhibitors<br />

• Derives 5-substitues 1,1-dioxo-[1,2,5]thiazolidine-3-one<br />

utilises en tant qu'inhibiteurs<br />

de PTPASE 1B<br />

(71) Novartis AG, Lichtstrasse 35, 4056 Basel, CH<br />

(72) Coppola, Gary Mark, Budd Lake, NJ 07828,<br />

US<br />

Davies, John William, Montclair, NJ 07042,<br />

US<br />

Jewel, Charles Francis, Jr., Sudbury, MA<br />

01776, US<br />

Li, Yu-Chin, Edison, NJ 08820, US<br />

Wareing, James Richard, Randolph, NJ<br />

07869, US<br />

Sperbeck, Donald Mark, Berkeley Heights, NJ<br />

07922, US<br />

Stams, Travis Mathew, Stow, MA 01775, US<br />

Topiol, Sidney Wolf, Fair Lawn, NJ 07410,<br />

US<br />

Vlattas, Isidoros, Summit, NJ 07901, US<br />

(74) Campbell, Lachlan Clive, Novartis Pharma AG<br />

<strong>Patent</strong> Department, 4002 Basel, CH<br />

(62) 03720412.0 / 1 492 780

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