Bulletin 2012/02 - European Patent Office
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(C07D) I.1(2)<br />

C07D 257/04 → (51) C07C 31/22<br />

C07D 261/12 → (51) C07C 31/22<br />

C07D 263/48 → (51) C07D 213/74<br />

(51) C07D 277/20 (11) 2 404 908 A1<br />

A61K 31/426 A61P 19/06<br />

A61P 43/00 C07D 277/56<br />

(25) Ja (26) En<br />

(21) 10746307.7 (22) 26.<strong>02</strong>.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) JP 2010/053043 26.<strong>02</strong>.2010<br />

(87) WO 2010/098428 2010/35 <strong>02</strong>.09.2010<br />

(30) 27.<strong>02</strong>.2009 JP 2009046003<br />

29.06.2009 JP 2009153770<br />

(54) • VERFAHREN ZUR HERSTELLUNG EINES<br />

PHENYL-SUBSTITUIERTEN HETEROCYC-<br />

LISCHEN DERIVATS MITTELS KOPPLUNG<br />

MIT EINEM ÜBERGANGSMETALLKATALY-<br />

SATOR<br />

• PROCESS FOR PRODUCING PHENYL-<br />

SUBSTITUTED HETEROCYCLIC DERIVA-<br />

TIVE THROUGH COUPLING USING TRAN-<br />

SITION METAL CATALYST<br />

• PROCÉDÉ DE PRODUCTION DE DÉRIVÉS<br />

HÉTÉROCYCLIQUES SUBSTITUÉS PAR UN<br />

PHÉNYLE PAR LE BIAIS D'UN COUPLAGE<br />

À L'AIDE D'UN CATALYSEUR À MÉTAL DE<br />

TRANSITION<br />

(71) Teijin Pharma Limited, 2-1, Kasumigaseki 3chome<br />

Chiyoda-ku, Tokyo 100-0013, JP<br />

(72) KOMIYAMA, Masato, Hino-shi Tokyo 191-<br />

0065, JP<br />

YAJIMA, Naoki, Hino-shi Tokyo 191-0065,<br />

JP<br />

KUROKAWA, Masayuki, Hino-shi Tokyo 191-<br />

0065, JP<br />

(74) Hallybone, Huw George, et al, Carpmaels &<br />

Ransford One Southampton Row, GB-London<br />

WC1B 5HA, GB<br />

C07D 277/42 → (51) C07D 213/74<br />

(51) C07D 277/46 (11) 2 404 909 A1<br />

C07D 417/12 C07D 277/58<br />

A61K 31/426 A61K 31/427<br />

A61P 3/10<br />

(25) Zh (26) En<br />

(21) 09832806.5 (22) 30.11.2009<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) CN 2009/001351 30.11.2009<br />

(87) WO 2010/069124 2010/25 24.06.2010<br />

(30) 16.12.2008 CN 200810154154<br />

(54) • AMIDTHIAZOLDERIVAT, VERFAHREN ZU<br />

SEINER HERSTELLUNG UND VERWEN-<br />

DUNG<br />

• AMIDE THIAZOLE DERIVATIVE, PREPAR-<br />

ATION METHOD AND USES THEREOF<br />

• DÉRIVÉ DE THIAZOLE DE TYPE AMIDE, SA<br />

MÉTHODE DE SYNTHÈSE ET SES APPLI-<br />

CATIONS<br />

(71) Tianjin Institute Of Pharmaceutical Research,<br />

No. 308 Anshan Xidao, Nankai District,<br />

Tianjin 300193, CN<br />

(72) ZHAO, Guilong, Tianjin 300193, CN<br />

XU, Weiren, Tianjin 300193, CN<br />

WANG, Yuli, Tianjin 300193, CN<br />

TANG, Lida, Tianjin 300193, CN<br />

LI, Yiliang, Tianjin 300193, CN<br />

ZOU, Meixiang, Tianjin 300193, CN<br />

LIU, Wei, Tianjin 300193, CN<br />

SHAO, Hua, Tianjin 300193, CN<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

TAN, Chubing, Tianjin 300193, CN<br />

LIU, Peng, Tianjin 300193, CN<br />

(74) Harrison IP Limited, 1st Floor, Box Tree<br />

House Northminster Business Park, Northfield<br />

Lane York, YO26 6QU, GB<br />

(51) C07D 277/56 (11) 2 404 910 A2<br />

A61K 31/426 A61P 19/06<br />

(25) En (26) En<br />

(21) 10185673.0 (22) 18.06.1999<br />

(84) AT BE CH CY DE DK ES FI FR GB GR IE IT LI<br />

LU MC NL PT SE<br />

AL LT LV MK RO SI<br />

(30) 19.06.1998 JP 17307998<br />

(54) • Polymorphe von 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolcarboxylsäure<br />

und Herstellungsverfahren dafür<br />

• Polymorphs of 2-(3-cyano-4-Isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic<br />

acid<br />

and method of producing the same<br />

• Polymorphes d'acide 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylique<br />

et son procédé de production<br />

(71) Teijin Pharma Limited, 2-1, Kasumigaseki 3chome<br />

Chiyoda-ku, Tokyo 100-0013, JP<br />

(72) Matsumoto, Kolchi, Yamaguchi Yamaguchi<br />

740-0014, JP<br />

Watanabe, Kenzo, Yamaguchi Yamaguchi<br />

740-0014, JP<br />

Hiramatsu, Toshiyuki, Yamaguchi Yamaguchi<br />

740-0014, JP<br />

Kitamura, Mitsutaka, Hiroshima Hiroshima<br />

739-0046, JP<br />

(74) Hallybone, Huw George, Carpmaels &<br />

Ransford One Southampton Row, London<br />

WC1B 5HA, GB<br />

(62) 08005933.0 / 1 956 014<br />

99957054.2 / 1 <strong>02</strong>0 454<br />

C07D 277/56 → (51) C07D 277/20<br />

C07D 277/58 → (51) C07D 277/46<br />

(51) C07D 295/18 (11) 2 404 911 A1<br />

C07D 211/14 C07D 207/06<br />

(25) En (26) En<br />

(21) 11183817.3 (22) 26.10.2006<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC NL PL PT RO<br />

SE SI SK TR<br />

AL BA HR MK RS<br />

(30) 31.10.2005 US 731941 P<br />

(54) • Neue Verfahren zur Herstellung von<br />

Piperazinyl- und Diazapanylbenzamidderivate<br />

• Novel processes for the preparation of<br />

piperazinyl and diazapanyl benzamide<br />

derivatives<br />

• Nouveaux procédés pour la préparation de<br />

dérivés de pipérazinyle et diazépanyle<br />

benzamide<br />

(71) Janssen Pharmaceutica NV, Turnhoutseweg<br />

30, 2340 Beerse, BE<br />

(72) Mani, Neelakandha S., San Diego, CA<br />

California 92129, US<br />

Pandit, Chennagiri R., San Diego, CA<br />

California 92129, US<br />

Reyes, Mayra B., 08873, NJ New Jersey<br />

Somerset, US<br />

Xiao, Tong, Edison, NJ New Jersey 08820,<br />

US<br />

Paömer, David C., Doylestown, PA Pennsylvania<br />

18901, US<br />

(74) Warner, James Alexander, Carpmaels &<br />

Ransford One Southampton Row, London<br />

WC1B 5HA, GB<br />

(62) 06826786.3 / 1 951 700<br />

222<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>02</strong>/<strong>2012</strong>) 11.01.<strong>2012</strong><br />

C07D 295/18 → (51) C07C 317/50<br />

(51) C07D 309/32 (11) 2 404 912 A2<br />

(25) En (26) En<br />

(21) 11177474.1 (22) 15.06.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

AL BA HR MK RS<br />

(30) 16.06.2006 EP 06380173<br />

(54) • Prozess und Intermediate zur Herstellung<br />

von Dihydropyran-2-on-Antitumorverbindungen<br />

• Process and intermediates for the preparation<br />

of antitumoral dihydropyran-2-one<br />

compounds<br />

• Procédé et intermédiaires pour la préparation<br />

de composés antitumoraux de dihydropyran-2-one<br />

(71) Pharma Mar S.A., Poligono Industrial La<br />

Mina Avda. de los Reyes 1 Colmenar Viejo,<br />

28770 Madrid, ES<br />

(72) Martín López, Mª Jesús, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Coello Molinero, Laura, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Reyes Benítez, José Fernando, E-28770<br />

Colmenar Viejo - Madrid, ES<br />

Rodríguez Vicente, Alberto, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Garranzo GarcÍa-Ibarrola, María, E-28770<br />

Colmenar Viejo - Madrid, ES<br />

Murcia Pérez, Carmen, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Francesch Solloso, Andrés, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Sánchez Sancho, Francisco, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Cuevas Marchante, María del Carmen, E-<br />

28770 Colmenar Viejo - Madrid, ES<br />

Fernández Rodríguez, Rogelio, E-28770<br />

Colmenar Viejo - Madrid, ES<br />

(74) Spring, Lauren Elizabeth, Marks & Clerk LLP<br />

62-68 Hills Road, Cambridge CB2 1LA, GB<br />

(62) 07765445.7 / 2 032 551<br />

(51) C07D 309/32 (11) 2 404 913 A2<br />

(25) En (26) En<br />

(21) 11177479.0 (22) 15.06.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

AL BA HR MK RS<br />

(30) 16.06.2006 EP 06380173<br />

(54) • Prozess und Intermediate zur Herstellung<br />

von Dihydropyran-2-on-Antitumorverbindungen<br />

• Process and intermediates for the preparation<br />

of antitumoral dihydropyran-2-one<br />

compounds<br />

• Procédé et intermédiaires pour la préparation<br />

de composés antitumoraux de dihydropyran-2-one<br />

(71) Pharma Mar S.A., Poligono Industrial La<br />

Mina Avda. de los Reyes 1 Colmenar Viejo,<br />

28770 Madrid, ES<br />

(72) Martín López, Mª Jesús, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Coello Molinero, Laura, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Reyes Benítez, José Fernando, E-28770<br />

Colmenar Viejo - Madrid, ES<br />

Rodríguez Vicente, Alberto, E-28770 Colmenar<br />

Viejo - Madrid, ES<br />

Garranzo GarcÍa-Ibarrola, María, E-28770<br />

Colmenar Viejo - Madrid, ES<br />

Murcia Pérez, Carmen, E-28770 Colmenar<br />

Viejo - Madrid, ES

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