Bulletin 2012/02 - European Patent Office

(C07D) II.1(1)
(51) C07D 409/10 (11) 1 869 023 B1
A61K 31/4178 A61P 9/00
A61P 1/00
(25) En (26) En
(21) 06726719.5 (22) 12.04.2006
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
(43) 26.12.2007
(86) GB 2006/001319 12.04.2006
(87) WO 2006/109048 2006/42 19.10.2006
(30) 12.04.2005 US 670251 P
(54) • NEUE TRICYCLISCHE ANGIOTENSIN-II-
AGONISTEN
• NEW TRICYCLIC ANGIOTENSIN II AGO-
NISTS
• NOUVEAUX AGONISTES TRICYCLIQUES
DE L'ANGIOTENSINE II
(73) Vicore Pharma AB, A+ Science AB/CRJ
Haraldsgatan 5, 413 14 Göteborg, SE
(72) ALTERMAN, Mathias, S-112 33 Stockholm,
SE
WU, Xiongyu, Department of Medicinal
Chemistry, S-75123 Uppsala, SE
HALLBERG, A., Department of Medicinal
Chemistry, S-51 23 Uppsala, SE
(74) McNeeney, Stephen Phillip, Potter Clarkson
LLP Park View House 58 The Ropewalk,
Nottingham NG1 5DD, GB
C07D 413/14 → (51) C07D 401/12
C07D 417/12 → (51) C07D 239/88
C07D 417/12 → (51) C07D 275/02
C07D 417/14 → (51) C07D 401/12
(51) C07D 471/04 (11) 1 881 983 B1
C07D 487/04 A61K 31/437
A61P 35/00
(25) En (26) En
(21) 06770824.8 (22) 22.05.2006
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
(43) 30.01.2008
(86) US 2006/019711 22.05.2006
(87) WO 2006/127587 2006/48 30.11.2006
(30) 20.05.2005 US 683554 P
(54) • PYRROLOPYRIDINE ALS PROTEINKINA-
SEHEMMER
• PYRROLOPYRIDINES USEFUL AS INHIBI-
TORS OF PROTEIN KINASE
• PYRROLOPYRIDINES UTILES EN TANT
QU'INHIBITEURS DE PROTEINES KINASES
(73) Vertex Pharmaceuticals, Inc., 130 Waverly
Street, Cambridge, MA 02139, US
(72) WANNAMAKER, Marion, W., Acton, MA
01720, US
LEDEBOER, Mark, W., Stow, MA 01775, US
PIERCE, Albert, C., Foxboro, MA 02035, US
WANG, Tiansheng, Concord, MA 01742, US
FARMER, Luc, J., Cambridge, MA 02139, US
MARTINEZ-BOTELLA, Gabriel, West Roxbury,
MA 02132, US
BEMIS, Guy, W., Lexington, MA 02420, US
BETHIEL, Randy, S., Arlington, MA 02476,
US
COME, Jon, H., Newton, MA 02461, US
ARNOST, Michael, J., North Andover, MA
01845, US
SALITURO, Francesco, G., North Andover,
MA 01845, US
WANG, Jian, Cambridge, MA 02139, US
MARHEFKA, Craig, Waltham, MA 02451, US
STEWART, Michelle, Cambrigde, MA 02138,
US
Europäisches Patentblatt
European Patent Bulletin
Bulletin européen des brevets
GREEN, Jeremy, Rockville, MD 20850, US
(74) Cohausz & Florack, Patent- und Rechtsanwälte
Partnerschaftsgesellschaft Bleichstraße
14, 40211 Düsseldorf, DE
(60) 10188694.3 / 2 354 139
10188700.8 / 2 354 140
10188704.0
C07D 471/04 → (51) C07D 209/82
C07D 471/04 → (51) C07D 217/24
(51) C07D 475/08 (11) 1 819 708 B1
A61K 31/519 A61P 35/00
(25) De (26) De
(21) 05849039.2 (22) 25.11.2005
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
(43) 22.08.2007
(86) EP 2005/056245 25.11.2005
(87) WO 2006/058868 2006/23 08.06.2006
(30) 29.11.2004 DE 102004057594
(54) • SUBSTITUIERTE PTERIDINE ZUR
BEHANDLUNG VON ENTZÜNDLICHEN
ERKRANKUNGEN
• SUBSTITUTED PTERIDINES FOR TREAT-
ING INFLAMMATORY DISEASES
• PTERIDINES SUBSTITUEES DESTINEES
AU TRAITEMENT DES MALADIES
INFLAMMATOIRES
(73) Boehringer Ingelheim International GmbH,
Binger Strasse 173, 55216 Ingelheim am
Rhein, DE
(84) AT BE BG CH CY CZ DK EE ES FI FR GB GR
HU IE IS IT LI LT LU LV MC NL PL PT RO SE
SI SK TR
(73) Boehringer Ingelheim Pharma GmbH & Co.
KG, Binger Strasse 173, 55216 Ingelheim am
Rhein, DE
(84) DE
(72) DOLLINGER, Horst, 88433 Schemmerhofen,
DE
MARTYRES, Domnic, 88400 Biberach, DE
MACK, Juergen, 88400 Biberach, DE
NICKOLAUS, Peter, 88447 Warthausen, DE
JUNG, Birgit, 88471 Laupheim, DE
(74) Hammann, Heinz, Boehringer Ingelheim
GmbH CD-Patents Binger Straße 173, 55216
Ingelheim am Rhein, DE
(51) C07D 487/04 (11) 1 888 066 B1
A61K 31/519 A61P 3/10
(25) En (26) En
(21) 06770752.1 (22) 19.05.2006
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
(43) 20.02.2008
(86) US 2006/019598 19.05.2006
(87) WO 2006/127530 2006/48 30.11.2006
(30) 25.05.2005 US 684567 P
(54) • AMINOCYCLOHEXANE ALS DIPEPTIDYL-
PEPTIDASE-IV-HEMMER ZUR BEHAND-
LUNG BZW. PRÄVENTION VON DIABETES
• AMINOCYCLOHEXANES AS DIPEPTIDYL
PEPTIDASE-IV INHIBITORS FOR THE
TREATMENT OR PREVENTION OF DIA-
BETES
• AMINOCYCLOHEXANES EN TANT QU'IN-
HIBITEURS DE DIPEPTIDYLE PEPTIDASE-
IV POUR LE TRAITEMENT OU LA PRE-
VENTION DU DIABETE
(73) Merck Sharp & Dohme Corp., 126 East
Lincoln Avenue, Rahway, NJ 07065, US
(72) BIFTU, Tesfaye, Rahway, NJ 07065-0907, US
FENG, Danqing, Rahway, NJ 07065-0907,
US
QIAN, Xiaoxia, Rahway, NJ 07065-0907, US
569
Patente
Patents
Brevets (02/2012) 11.01.2012
WEBER, Ann, E., Rahway, NJ 07065-0907,
US
COX, Jason, Rahway, NJ 07065-0907, US
(74) Buchan, Gavin MacNicol, et al, Merck Sharp
& Dohme Limited European Patent Department
Hertford Road, Hoddesdon Hertfordshire
EN11 9BU, GB
(51) C07D 487/04 (11) 1 891 072 B1
A61K 31/551
(25) En (26) En
(21) 06759877.1 (22) 16.05.2006
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
AL BA HR MK YU
(43) 27.02.2008
(86) US 2006/018796 16.05.2006
(87) WO 2006/124813 2006/47 23.11.2006
(30) 18.05.2005 US 682290 P
(54) • Substituierte 7,8-Dihydro-1H-pyrimido[4,5b]diazepin-4-amine
als Kinase Inhibitoren
• Substituted 7,8-Dihydro-1H-pyrimido[4,5b]diazepin-4-amines
as kinase inhibitors
• 7,8-Dihydro-1H-pyrimido[4,5-b]diazepin-
4-amines substiuées en tant qu'inhibiteurs
de kinase
(73) ABBOTT LABORATORIES, CHAD 0377/
AP6A-1 100 Abbott Park Road, Abbott Park
IL 60064-3500, US
(72) GRACIAS, Vijaya, J., Lindenhurst, IL 60046,
US
ABAD-ZAPATERO, Celerino, Lake Forest, IL
60045, US
DJURIC, Stevan, W., Libertyville, IL 60048,
US
JI, Zhiqin, Libertyville, IL 60048, US
MICHAELIDES, Michael, R., Libertyville, IL
60048, US
STEWART, Kent, D., Gurnee, IL 60031, US
ZANZE, Irini, Libertyville, IL 60048, US
(74) Modiano, Micaela Nadia, Modiano Josif
Pisanty & Staub Ltd Thierschstrasse 11,
80538 München, DE
(51) C07D 487/04 (11) 1 913 000 B1
C07D 211/56
(25) En (26) En
(21) 06779900.7 (22) 17.07.2006
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HU IE IS IT LI LT LU LV MC NL PL PT RO
SE SI SK TR
(43) 23.04.2008
(86) IB 2006/002048 17.07.2006
(87) WO 2007/012953 2007/05 01.02.2007
(30) 29.07.2005 US 704011 P
(54) • PYRROLO[2,3-D]PYRIMIDINDERIVATE,
IHRE ZWISCHENPRODUKTE UND SYN-
THESE
• PYRROLO[2,3-D]PYRIMIDINE DERIVA-
TIVES; THEIR INTERMEDIATES AND
SYNTHESIS
• DERIVES DE PYRROLO[2,3-D]PYRIMI-
DINE, LEURS INTERMEDIAIRES ET LEUR
SYNTHESE
(73) Pfizer Products Inc., Eastern Point Road,
Groton, CT 06340, US
(72) RUGGERI, Sally Gut, Groton, CT 06340, US
HAWKINS, Joel Michael, Groton, CT 06340,
US
MAKOWSKI, Teresa Margaret, Groton, CT
06340, US
RUTHERFORD, Jennifer Lea, Groton, CT
06340, US
URBAN, Frank John, Old Sybrook, CT 06475,
US