Bulletin 2012/02 - European Patent Office
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(C07D) II.1(1)<br />

• 1- Ý[- (2, 4-DIMETHYLPHENYLSULFANYL)<br />

-PHENYL]PIPERAZINE AS A COMPOUND<br />

WITH COMBINED SEROTONIN REUPTAKE,<br />

5-HT3 AND 5-HT1A ACTIVITY FOR THE<br />

TREATMENT OF COGNITIVE IMPAIRMENT<br />

• 1-[2-(2, 4-DIMETHYLPHENYLSULFANYL)-<br />

PHENYL]PIPERAZINE COMME COMPOSE<br />

PRESENTANT UNE ACTIVITE SUR LA<br />

SEROTONINE, 5-HT3 ET 5-HT1A POUR LE<br />

TRAITEMENT DU DEFICIT COGNITIF<br />

(73) H. Lundbeck A/S, Ottiliavej 9, 2500 Valby-<br />

Copenhagen, DK<br />

(72) BANG-ANDERSEN, Benny, 2300 Copenhagen<br />

S, DK<br />

FALDT, André, 2635 Ishøj, DK<br />

MØRK, Arne, 2760 Måløv, DK<br />

LOPEZ DE DIEGO, Heidi, 2850 Nærum, DK<br />

HOLM, René, 4040 Jyllinge, DK<br />

STENSBØL, Tine Bryan, 3500 Værløse, DK<br />

RINGGAARD, Lone Munch, 2400 Copenhagen<br />

NV, DK<br />

MEALY, Michael J., 4320 Lejre, DK<br />

ROCK, Michael Harold, 2650 Hvidovre, DK<br />

BRODERSEN, Jørgen, 4300 Holbæk, DK<br />

JØRGENSEN, Morten, 2880 Bagsværd, DK<br />

MOORE, Nicholas, Ridgewood, New Jersey<br />

07450, US<br />

C07D 303/04 → (51) C07B 41/00<br />

C07D 307/33 → (51) C07B 41/00<br />

C07D 307/89 → (51) C07B 41/00<br />

C07D 311/72 → (51) C07H 15/203<br />

C07D 317/00 → (51) A61K 31/44<br />

C07D 339/04 → (51) C07H 15/203<br />

C07D 401/04 → (51) C07D 217/24<br />

(51) C07D 401/06 (11) 2 173 735 B1<br />

C07D 401/14 C07D 403/06<br />

C07D 405/14 A61K 31/4178<br />

A61K 31/4439 A61P 9/00<br />

(25) En (26) En<br />

(21) 08774212.8 (22) 23.06.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(43) 14.04.2010<br />

(86) EP 2008/057934 23.06.2008<br />

(87) WO 2009/003861 2009/<strong>02</strong> 08.01.2009<br />

(30) <strong>02</strong>.07.2007 EP 07111552<br />

(54) • IMIDAZOLDERIVATE ALS CCR2-REZEP-<br />

TOR-ANTAGONISTEN<br />

• IMIDAZOLE DERIVATIVES AS CCR2<br />

RECEPTOR ANTAGONISTS<br />

• DÉRIVÉS IMIDAZOLÉS COMME ANTAGO-<br />

NISTES DU RÉCEPTEUR CCR2<br />

(73) F. Hoffmann-La Roche AG, Grenzacherstrasse<br />

124, 4070 Basel, CH<br />

(72) AEBI, Johannes, CH-41<strong>02</strong> Binningen, CH<br />

BINGGELI, Alfred, CH-41<strong>02</strong> Binningen, CH<br />

GREEN, Luke, CH-4057 Basel, CH<br />

HARTMANN, Guido, 79539 Loerrach, DE<br />

MAERKI, Hans P., CH-4059 Basel, CH<br />

MATTEI, Patrizio, CH-4125 Riehen, CH<br />

RICKLIN, Fabienne, F-68490 Hombourg, FR<br />

ROCHE, Olivier, F-68220 Folgensbourg, FR<br />

(74) Heiroth, Ulrike Hildegard, F. Hoffmann-La<br />

Roche AG <strong>Patent</strong> Department, Grenzacherstrasse<br />

124, CH-4070 Basel, CH<br />

C07D 401/06 → (51) C07D 217/24<br />

C07D 401/06 → (51) C07D 217/26<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

C07D 401/06 → (51) C07D 233/76<br />

C07D 401/06 → (51) C07D 239/32<br />

C07D 401/06 → (51) C07D 239/90<br />

(51) C07D 401/12 (11) 1 870 100 B1<br />

(25) De (26) De<br />

(21) 07115663.2 (22) 03.03.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT RO SE SI SK<br />

TR<br />

(43) 26.12.2007<br />

(30) 07.03.20<strong>02</strong> DE 1<strong>02</strong>09985<br />

30.09.20<strong>02</strong> DE 1<strong>02</strong>45624<br />

(54) • 3-[(2-{[4-(Hexyloxycarbonylamino-iminomethyl)-phenylamino]methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-ylamino]-propionsäure-ethylesterMethansulfonat<br />

• Ethyl 3-(2-(4-(hexyloxycarbonylamidino)<br />

phenylaminomethyl)-1-methyl-1H-benzimidazole-5-carbonyl)-2-pyridylamino)propionate<br />

methansulfonate<br />

• Méthanesulfonate d'éthyl-(2-(4-(héxyloxycarbonylamidino)phénylaminométhyl)-1méthyl-1H-benzimidazole-5-carbonyl)-2pyridylamino)propionate<br />

(73) Boehringer Ingelheim Pharma GmbH & Co.<br />

KG, Binger Straße 173, 55216 Ingelheim am<br />

Rhein, DE<br />

(72) Brauns, Ulrich, 88400, BIBERACH, DE<br />

Hauel, Norbert, 88433, SCHEMMERHOFEN,<br />

DE<br />

(62) 03743368.7 / 1 485 094<br />

(51) C07D 401/12 (11) 2 152 690 B1<br />

C07D 401/14 C07D 413/14<br />

A61K 31/4525 A61P 25/00<br />

A61K 31/454 A61K 31/4535<br />

A61K 31/506 C07D 417/14<br />

(25) En (26) En<br />

(21) 08754659.4 (22) 22.05.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

RS<br />

(43) 17.<strong>02</strong>.2010<br />

(86) US 2008/006563 22.05.2008<br />

(87) WO 2008/147518 2008/49 04.12.2008<br />

(30) 23.05.2007 US 931458 P<br />

(54) • PYRIDYLPIPERIDINOREXIN-REZEPT-<br />

ORANTAGONISTEN<br />

• PYRIDYL PIPERIDINE OREXIN RECEPTOR<br />

ANTAGONISTS<br />

• ANTAGONISTES DE RÉCEPTEUR D'ORE-<br />

XINE PIPÉRIDYL PIPÉRIDINE<br />

(73) Merck Sharp & Dohme Corp., 126 East<br />

Lincoln Avenue, Rahway, NJ 07065, US<br />

(72) BRESLIN, Michael, J., Rahway, NJ 07065-<br />

0907, US<br />

COLEMAN, Paul, J., Rahway, NJ 07065-<br />

0907, US<br />

COX, Christopher, D., Rahway, NJ 07065-<br />

0907, US<br />

SCHREIER, John, D., Rahway, NJ 07065-<br />

0907, US<br />

(74) Buchan, Gavin MacNicol, Merck & Co., Inc.<br />

<strong>European</strong> <strong>Patent</strong> Department Hertford Road,<br />

Hoddesdon, Hertfordshire EN11 9BU, GB<br />

(51) C07D 401/12 (11) 2 173 737 B1<br />

C07D 401/14 A61K 31/454<br />

A61P 3/10<br />

(25) En (26) En<br />

(21) 08781868.8 (22) 16.07.2008<br />

568<br />

<strong>Patent</strong>e<br />

<strong>Patent</strong>s<br />

Brevets (<strong>02</strong>/<strong>2012</strong>) 11.01.<strong>2012</strong><br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(43) 14.04.2010<br />

(86) US 2008/070103 16.07.2008<br />

(87) WO 2009/012277 2009/04 22.01.2009<br />

(30) 17.07.2007 US 950162 P<br />

(54) • VERFAHREN ZUR MODULATION DES<br />

GPR119-G-PROTEINGEKOPPELTEN<br />

REZEPTORS UND AUSGEWÄHLTE VER-<br />

BINDUNGEN<br />

• METHOD FOR MODULATING GPR119 G<br />

PROTEIN-COUPLED RECEPTOR AND<br />

SELECTED COMPOUNDS<br />

• PROCÉDÉ DE MODULATION DE RÉCEP-<br />

TEUR GPR119 DE LA PROTÉINE G ET<br />

COMPOSÉS SÉLECTIONNÉS<br />

(73) Bristol-Myers Squibb Company, Route 206<br />

and Province Line Road P.O. Box 4000,<br />

Princeton NJ 08543-4000, US<br />

(72) WACKER, Dean A., Pennington, NJ 08534,<br />

US<br />

ROSSI, Karen A., Pennington, NJ 08534, US<br />

WANG, Ying, Pennington, NJ 08534, US<br />

(74) Reitstötter - Kinzebach, <strong>Patent</strong>anwälte<br />

Sternwartstrasse 4, 81679 München, DE<br />

C07D 401/12 → (51) C07D 239/88<br />

C07D 401/14 → (51) C07D 233/76<br />

C07D 401/14 → (51) C07D 401/06<br />

C07D 401/14 → (51) C07D 401/12<br />

C07D 403/04 → (51) C07D 239/52<br />

C07D 403/06 → (51) C07D 217/26<br />

C07D 403/06 → (51) C07D 401/06<br />

C07D 403/12 → (51) C07D 239/88<br />

C07D 405/12 → (51) C07D 239/90<br />

C07D 405/14 → (51) C07D 401/06<br />

(51) C07D 407/04 (11) 2 <strong>02</strong>7 115 B1<br />

C07D 493/10 A61K 31/35<br />

A61P 35/00<br />

(25) En (26) En<br />

(21) 07736845.4 (22) 10.05.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

(43) 25.<strong>02</strong>.2009<br />

(86) IT 2007/000342 10.05.2007<br />

(87) WO 2007/132496 2007/47 22.11.2007<br />

(30) 15.05.2006 IT RM2006<strong>02</strong>57<br />

(54) • DIOXASPIROKETALDERIVATE, VERFAH-<br />

REN ZU IHRER HERSTELLUNG UND<br />

ANWENDUNGEN DAVON<br />

• DIOXASPIROKETAL DERIVATIVES, PRO-<br />

CESS FOR THEIR PREPARATION AND<br />

USES THEREOF<br />

• DÉRIVÉS DE DIOXASPIROCÉTAL, PRO-<br />

CÉDÉ DE PRÉPARATION ET UTILISATIONS<br />

DE CES DÉRIVÉS<br />

(73) CNR Consiglio Nazionale Delle Ricerche,<br />

Piazzale Aldo Moro, 7, 00185 Roma, IT<br />

(72) DE MICO, Antonella, 00185 Roma, IT<br />

COTTARELLI, Andrea, 00137 Roma, IT<br />

FUGGETTA, Mariapia, 00137 Roma, IT<br />

LANZILLI, Giulia, 00137 Roma, IT<br />

TRICARICO, Maria, 00137 Roma, IT<br />

(74) Iannone, Carlo Luigi, Barzanò & Zanardo<br />

Roma S.p.A. Via Piemonte 26, 00187 Roma,<br />

IT

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