MONOGRAFÍA CANNABIs - Asociación Española de Patología Dual

cannabidiol following oral administration inman. Assay of cannabinol and cannabidiol bymass fragmentography. Experientia 37:1090-1.Agurell S., Halldin M., Lindgren J., Ohlsson A., WidmanM., Gillespie H., Hollister L. (1986) Pharmacokineticsand metabolism of ácido ∆ 9 -THCand other cannabinoids with emphasis on man,Pharmacol. Rev. 38:21-42.Azorlosa J.L., Greenwald M.K., Stitzer M. (1995)Marihuana smoking: effects of varying puffvolume and breathhold duration. J. PharmacolExp. Ther. 272:560-569.Baczynsky W.O.T., Zimmerman A.M. (1983) Effectsof D9-tetrahydrocannabinol, cannabinol andcannabidiol on the immune system in mice. II.In vitro investigation using cultured mousesplenocytes. Pharmacology 26:12-19.Baily L.H. (1949) Manual of cultivated plants. (2nded.) Macmillan Co. New York.Bell M.R., D’Ambra T.E., Kumar V., Eissenstat M.A.,Herrman J.L. (1991) Antinociceptive (aminoalkyl)-indoles.J. Med. Chem. 34:1099-1110.Bornheim L.M., Everhart E.T., Li J., Correia M.A.(1994). Induction and genetic regulation ofmouse hepatic cytochrome P-450 by cannabidiolBiochem. Pharmacol 48:161-71.Bornheim L.M., Kim K.Y., Li J., Perotti B.Y.T., BenetL.Z. (1995) Effect of cannabidiol pretreatmenton the kinetics of tetrahydrocannabinol metabolitesin mouse brain. Drug Metabolism andDisposition. 23: 825-831.Bouquet R.J. (1951) Cannabis. Bull. Narc. 3:14-30Brown N.K., Harvey D.J. (1990a) Comparative invitro metabolism of cannbinol in rat, mouse,rabbit, guinea pig, hamster, gerbil and cat. Eur.J. Drug Metab. Pharmacokinetics 15:253-8.Brown N.K., Harvey D.J. (1990b). In vitro metabolismof cannabichromene in 7 common laboratoryanimals. Drug Metab. Dispos. 16:1065-70.Burstein S., Hunter S.A., Latham V., Renzulli L.(1986) Prostaglandins and cannabis. XIV. Antagonismof ∆ 1 -THC action by its metabolites.Biochem Pharmacol 35:2553-8Burstein S., Hunter S.A., Latham V., Renzulli L.(1987) A major metabolite of ∆ 1 -THC reduces itscataleptic effect in mice. Experientia 43:402-3.Burstein S. (1999) The cannabinoid acids: nonpsychoactivederivatives with therapeutic potential.Pharmacol Ther. 82:87-96.Condie R., Herring A., Koh W.S., Lee M., KaminskiN.E. (1996) Cannabinoid inhibition of adenylatecyclase-mediated signal transduction and interleukin2 (IL-2) expression in the murine T-cellline, EL4.IL-2. J. Biol. Chem. 271:13175-13183.Cone E.J., Huestis M.A. (1993) Relating blood concentrationsof tetrahydrocannabinol and metabolitesto pharmacologic effects and time ofmarihuana usage. Therapeutic Drug Monitoring15:527-532.Consroe P., Sandyk R. (1992) Potential role od cannabinoidsfor therapy of neurological disorders.En Marihuana/Cannabinoids: Neurobiology andNeurophysiology, Bartke A., Murphy L.L., eds.,Biochemistry and physiology os substanceabuse, vol IV, CRC Press, Boca Ratón, FL, pgs.459-524.Dewey L.H. (1928). Hemp varieties of improvedtype are result of selection. U.S.D.A. Yearbook,1927:358-61.Dewey W.L. Martin B.R., May E.L. (1984). Cannabinoidstereoisomers: pharmacological effects,en Handbook of Stereoisomers: Drugs inPsychopharmacology. Smith D.F. Ed. CRCPress, Boca Raton FL, pgs. 317-354.Eckler C.R., Miller F.A. (1912). A study of Americangrown Cannabis in comparison with samplesfrom various other sources. Am. J. Pharm.84:488-95.Fernández-Ruiz J.J.. Rodríguez F., Navarro M.,Ramos J.A. (1992) Maternal cannabinoid exposureand brain development: changes in theontogeny of dopamine neurons. En Marihuana/Cannabinoids:Neurobiology and Neurophysiology,Bartke A., Murphy L.L., eds., Biochemistryand physiology os substance abuse, volIV, CRC Press, Boca Ratón FL, pgs. 119-164.Garret E.R., Gouyette A.J., Roseboom H. (1978).Stability of tetrahydrocannabinols II J. Pharm.Sci. 67:27-32.Green K. (1999) Marihuana and intraocular pressure.Possible mechanisms of action. En Marihuanaand Medicine, Nahas G.G., Sutin K.M.,Harvey D.J., Agurell S., eds., Humana Press,Totowa, NJ, pgs. 581-9.Hampson A.J., Grimaldi M., Axelrod J., Wink D.,(1998) Cannabidiol and (-)δ 9 -tetrahydrocannabinolare neuroprotective antioxidants. Proc. Natl.Acad. Sci. USA 95:8268-8273.Harvey D.J. (1984) Chemistry, metabolism andpharmacokinetics of the cannabinoids. EnNahas G.G., ed.. Raven Press. New York, pgs.37-107.Ramos, J.A.; Fernández, J. 55