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Handbook of Solvents - George Wypych - ChemTech - Ventech!

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18.4 Solvent uses with exposure risks 1263<br />

nary cyclohexanol level <strong>of</strong> 54.5 mg/l (23.3 mg/g creatinine) was found to correspond<br />

inhalation exposure to 25 ppm <strong>of</strong> cyclohexanone. 75<br />

18.4.11 SUMMARY<br />

Even though organic solvents have been increasingly replaced by water-based and solid formulations,<br />

they are still widely used. About 3% <strong>of</strong> the Finnish working population has estimated<br />

to have significant solvent exposure. 26 It should also be noted that solventless<br />

products may cause new health problems and the knowledge <strong>of</strong> the health risks <strong>of</strong> the substitutions<br />

is <strong>of</strong>ten poor. 43<br />

An extensive survey <strong>of</strong> chemical exposure conducted by FIOH in Finland in the<br />

1980’s. The highest exposure levels were detected in shoe gluing, painting <strong>of</strong> furniture and<br />

other wood products, silkscreen and rotogravure printing, floor lacquering, reinforced plastics<br />

production, paint removing, metal degreasing, and various solvent cleaning operations.<br />

25,45,64<br />

Mostly, inhalation exposure can be effectively controlled by enclosures and ventilation.<br />

Open mold methods in the reinforced plastics industry and paint stripping, however,<br />

require sophisticated ventilation arrangements. High exposures <strong>of</strong>ten occur during solvent<br />

cleaning operations. Exposure levels may be very high while cleaning pots in paint and<br />

printing ink industry. The use <strong>of</strong> a proper respirator is necessary during such a work. The<br />

avoidance <strong>of</strong> high peak exposures is important also to prevent development <strong>of</strong> addiction.<br />

The workers may adopt working habits that cause unnecessary exposure. In extreme causes,<br />

even this may lead to solvent sniffing. 24<br />

Recent studies have revealed that percutaneous absorption is <strong>of</strong>ten an important route<br />

<strong>of</strong> solvent exposure. As the control <strong>of</strong> respiratory exposures develops, the relative importance<br />

<strong>of</strong> dermal exposures increases.<br />

REFERENCES<br />

1 C. Hogstedt, Scand. J. Work Environ. Health, 20, 59 (1994).<br />

2 C. Edling, A. Lindberg, and J. Ulfberg, Br. J. Ind. Med., 50, 276 (1993).<br />

3 L. Barregård and A. Axelsson, Scand. Audiol., 13, 151 (1984).<br />

4 L. Low, J. Meeks, and C. Mackerer in Ethel Browning’s Toxicity and Metabolism <strong>of</strong> Industrial <strong>Solvents</strong>,<br />

R. Snyder, Ed., Elsevier, Amsterdam, 1987, pp. 297-311.<br />

5. D. Couri and M.Milks, Annual Review <strong>of</strong> Pharmacology and Toxicology, 22, 145 (1982).<br />

6 S. Sjöberg., J .Dahlqvist, S. Fregert, Contact Dermatitis, 8, 207 (1982).<br />

7 A. Tossavainen and J. Jaakkola, Appl. Occup. Environ. Hyg., 9, 28 (1994).<br />

8 P. Delore and C. Borgomano, J. Med. Lyon, 9, 227 (1928).<br />

9 IARC Monographs on the Evaluation <strong>of</strong> Carcinogenic Risks to Humans, Vol. 47, Lyon, 1989.<br />

10 D. McGregor, E. Heseltine, and H. Moller, Scand. J. Work Environ. Health, 21, 310 (1995).<br />

11 A. Anttila, E. Pukkala, R. Riala et al., Int. Arch. Occup. Environ. Health, 71, 187 (1998).<br />

12 H-W. Leung and D. Paustenbach, Appl. Occup. Environ. Hyg., 9, 187 (1994).<br />

13 G. Johanson and A. Boman, Br. J. Ind. Med., 48, 788 (1991).<br />

14 V. Fiserova-Bergerova, Ann. Occup. Hyg., 34, 639 (1990).<br />

15 ACGIH, TLVs and BEIs, 1999<br />

16 R. Soule in Patty’s Industrial Hygiene and Toxicology, G. Clayton and F. Clayton, Eds, Vol.1, Part A,<br />

John Wiley and Sons, New York, 1991, pp. 137-194.<br />

17 E. Andersson, N. Browne, S. Duletsky et al. Development <strong>of</strong> Statistical Distributions <strong>of</strong> Ranges <strong>of</strong> Standard<br />

Factors Used in Exposure Assessments, National Technical Information Service, U.S. Department <strong>of</strong><br />

Commerce, 1985.<br />

18 B-S. Cohen and W. Popendorf, Am. Ind. Hyg. Assoc. J., 50, 216 (1989).<br />

19 J. Perkins and B. Pool, Am. Ind. Hyg. Assoc. J., 58, 474 (1997).<br />

20 P. Kalliokoski, Am. Ind. Hyg. Assoc. J., 51, 310 (1990).<br />

21 I. Lundberg and R. Milatou-Smith, Scand. J. Work Environ.& Health, 24, 270 (1998).

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