LINEAR ALKYLBENZENE SULFONATE (LAS) - UNEP Chemicals

OECD SIDS LINEAR ALKYLBENZENE SULFONATE (LAS)
IV. Inputs, Outputs, and Quality Description
(1) Media Modeled
The exposure media are the LAS-containing products used by consumers. The LAS Coalition fielded a
survey among producers and formulators to establish the range of LAS concentrations in each of the product
forms. For each product category containing LAS, the minimum and maximum of the range were utilized as
inputs for the dermal exposure models.
(2) Inputs
The dermal exposure scenarios encompass conservative, screening-level inputs including: the high-end
frequency of product use, the high-end amount of product per use, the high-end percent of product retained
on skin or clothes following use. Also, actual dermal absorption is only about 1% of product (Schaefer and
Redelmeier 1996), whereas all modeled exposures include a default assumption of 100%. Thus, the modeled
exposure is conservative by a factor of at least 100 based on absorption alone. LAS coalition member
companies provided formulation information on the range of LAS concentrations in specified product types
to be used in this assessment.
Exposure during the activity/use of diluted and undiluted laundry and dishwashing products,
and diluted and undiluted hard surface cleaning products
Laundry
Pretreatment
(diluted)
[FQ x CA x PC x FT x CF x TF x DA] x PF
BW
Neat
Laundry
Pretreatment
(undiluted)
Handwash
of
Laundry
(diluted)
Handwash
of
Dishes
(diluted)
Handwash
of
hands
with dish
liquid
(diluted)
Hard
Surface
Cleaners
(diluted)
Hard
Surface
Cleaners
(undiluted)
Frequency (FQ)
(use/day)
1 h 1 h 1 h 3 h 0.14 h 1 h 1 h
Contact Area (CA)
(cm 2 )
360 b 360 b 1680 f 1680 f 1680 f 1680 f 180 j
Product
Concentration
(PC) (g/cm 3 )
0.6 a 1 a 0.01 a 0.0015 a 0.9 g 0.01 a 1 a
Film Thickness
(FT) (cm)
0.0024 c 0.0024 c 0.0024 c 0.0024 c 0.0024 c 0.0024 c 0.0024 c
Conversion Factor
(CF) (1000 mg/g)
Time Scaling
1000 1000 1000 1000 1000 1000 1000
Factor (TF)
(unitless)
0.007 d 0.007 d 0.007 d 0.03 d .00035 d 0.014 h 0.014 h
Dermal Absorption
(DA) (%)
100% i 100% i 100% i 100% i 100% i 100% i 100% i
Female body
weight (BW) (kg)
60 e 60 e 60 e 60 e 60 e 60 e 60 e
LAS concentration
in product
formulation (PF) g
(%)
References:
5-10% 5-10% 1-25% 5-25% 5-25% 1-5% 1-5%
a: LAS Coalition survey
b: Palms surface area (EPA Exposure Factors Handbook)
c: EPA 560/5-85-007, Methods of assessing exposure to chemical substances, Vol.7, Versar, 1985
d: HERA project
e: Female body weight (EU Technical Guidance Document, 1996)
f: Hands and forearms (EPA Exposure Factors Handbook)
g: LAS Coalition survey, Min-Max values
h: SDA Habit and Practice Survey
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