LINEAR ALKYLBENZENE SULFONATE (LAS) - UNEP Chemicals

OECD SIDS LINEAR ALKYLBENZENE SULFONATE (LAS)
Hand-wash of Dishes (diluted) 5.0E-4 to 2.3E-3
Hand-wash (dishwashing liquids) of hands
(diluted)
1.0E-4 to 7.4E-4
Hard Surface Cleaners (diluted) 1.0E-3 to 5.0E-4
Hard Surface Cleaners (undiluted) 5.0E-3 to 1.0E-3
a
range based on minimum and maximum product concentration values
Exposure to laundry and fabric conditioning product residual on clothing
Potential Dermal Exposure
(mg/kg/day) a
Liquid Laundry Detergent 2.0E-3 to 5.0E-2
Dry Laundry Detergent 1.0E-2 to 5.0E-2
Tablet Laundry Detergent 1.1E-2 to 5.6E-2
Fabric conditioning (dryer sheets) 5.0E-5 to 3.0E-4
a range based on minimum and maximum product concentration values
Exposure to face and hand soap residual after use
Potential Dermal Exposure
(mg/kg/day) a
Bar Soap – Hand 3.6E-3 to 1.8E-2
Bar Soap - Face 5.0E-4 to 2.3E-3
a range based on minimum and maximum product concentration values
(4) Reliability Score 1 (Reliable without restrictions) The models used are first principle equations,
which are sufficiently conservative, have undergone peer review and are generally accepted by authorities.
Appropriate inputs have been used, reflecting best available information and conservative estimates where
applicable.
(5) Remarks
An appropriate NOAEL from animal studies for use as a comparison is 85 mg/kg. Estimated
dermal exposures in consumer products range from a low of 0.000047 to a high of 0.056
mg/kg/day.
These human exposure evaluations include conservative (protective) input and model assumptions (e.g. all
modeled exposures are conservative by a factor of at least 100 due to use of a default assumption of 100%
absorption vs. a measured value of