The exposure and toxicity of pesticides to amphibians

Pesticide %
a.i.
Test
material
Species Stage Temp.
°C
DFP NR Tech. Bufo viridis Adult
(18-
45g)
Diazinon 89 NR Rana
catesbeiana
Dicrotophos 98 NR Rana
catesbeiana
Dimefox NR Tech. Bufo viridis Adult
(18-
45g)
Exposure
type
25 Injection
(dorsal
lymph sac)
NR NR Oral
(capsule)
NR NR Oral
(capsule)
25 Injection
(dorsal
lymph sac)
Amphibians and pesticides
Supporting publications 2012:EN-343 86
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Dur.
(h)
Dose
levels
Anim.
/dose
LD50
(mg/kg)
(95%
CL)
Comments Reference
NR NR NR 1450 Data appears to be for
active ingredient.
Minimum 25 animals.
Toxicity to white mice
was 4.0mg/kg
(subcutaneous).
336 NR NR >2000 Basis of LD50 value
unclear, assume active
ingredient based on
purity. Based on data for
4 females. Toxicity to 3-4
months old mallard
336 NR NR 2000
(602-
6640)
3.54g/kg.
Basis of LD50 value
unclear, assume active
ingredient based on
purity. Based on data for
8 males. Test material is
98% α isomer. Toxicity to
3 months old mallard
4.24mg/kg. Toxicity to
2.5 month old Japanese
quail 4.32mg/kg.
NR NR NR 1410 Data appears to be for
active ingredient.
Minimum 25 animals.
Toxicity to white mice
was 4.4mg/kg
(intraperitoneal).
Edery and
Schatzberg-
Porath (1960)
Hudson et al
(1984)
Hudson et al
(1984)
Edery and
Schatzberg-
Porath (1960)