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History of Natto and Its Relatives (1405-2012 - SoyInfo Center

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substances contained in natto, depressor effects, carcinostatic<br />

effects, <strong>and</strong> dissipation <strong>of</strong> the effects <strong>of</strong> alcoholic drinks,<br />

preventive effects for osteoporosis. Tempeh: Strong<br />

antibacterial activity <strong>and</strong> effectiveness against intestinal<br />

disorders, antioxidant, antiallergic, <strong>and</strong> beauty care effects,<br />

starters for tempeh <strong>and</strong> high nutritional value. Shoyu (soy<br />

sauce): Antibacterial, antioxidation, <strong>and</strong> depressor effect,<br />

antitumor effects. Miso (soybean paste): Effectiveness <strong>of</strong><br />

soybean paste for cancer prevention, depressor effects,<br />

antioxidation <strong>and</strong> antiradioactivity effects. T<strong>of</strong>uyo.<br />

Tables: (1) Dipicolic acid in natto <strong>and</strong> Bacillus subtilis<br />

natto. (2) Fibrinolytic activity in human plasma after the<br />

intake <strong>of</strong> natto. (3) Expired gas <strong>and</strong> intestinal gas after<br />

intake <strong>of</strong> tempeh. (4) Is<strong>of</strong>l avone content in tempeh. (5)<br />

Antioxidation activity <strong>of</strong> the aromatic components <strong>of</strong> shoyu<br />

(soy sauce). (6) Functional effects <strong>of</strong> melanoidine contained<br />

in shoyu (soy sauce) <strong>and</strong> miso (soybean paste).<br />

Figures: (1) Graph <strong>of</strong> the effects on O-157 as a result <strong>of</strong><br />

the addition <strong>of</strong> natto bacillus. (2) Graph <strong>of</strong> the effects on H.<br />

pylori (Sydney strain) resulting from the addition <strong>of</strong> natto<br />

extracts. (3) Photo <strong>of</strong> fi brinolytic activity <strong>of</strong> natto. A piece<br />

<strong>of</strong> natto commonly sold on the market was placed in a petri<br />

dish with artifi cial thrombus. (4) The molecular structure <strong>of</strong><br />

nattokinase. (5) Photo <strong>of</strong> fi brinolytic activity <strong>of</strong> nattokinase.<br />

(6) 3 graphs <strong>of</strong> changes in the fi brinolytic parameters<br />

in the blood after oral administration <strong>of</strong> nattokinase to<br />

human volunteers. (7) Graph <strong>of</strong> the effects <strong>of</strong> natto extracts<br />

on blood pressure. (8) Graph <strong>of</strong> the inhibitor activity <strong>of</strong><br />

platelet aggregation. (9) 2 graphs <strong>of</strong> the concentration <strong>of</strong><br />

vitamin K 2 in human blood after the intake <strong>of</strong> natto. (10)<br />

Bar chart <strong>of</strong> change in the concentration <strong>of</strong> menaquinone-7<br />

in plasma after ingestion <strong>of</strong> natto. (11) Graph <strong>of</strong> the effects<br />

<strong>of</strong> the tempeh bacteria on afl atoxin-producing bacteria.<br />

(12) Diagrams <strong>of</strong> the aromatic components <strong>of</strong> shoyu (soy<br />

sauce). (13) Bar chart <strong>of</strong> the effects <strong>of</strong> the concentration <strong>of</strong><br />

nitrous acid on the antitumor activity <strong>of</strong> shoyu (soy sauce).<br />

(14) Chart <strong>of</strong> the carcinogenesis inhibitor effects <strong>of</strong> HEMF<br />

against proventriculus tumors induced by benzo[a]pyrene.<br />

(15) Bar chart <strong>of</strong> st<strong>and</strong>ardized mortality from stomach cancer<br />

relative to the level <strong>of</strong> frequency <strong>of</strong> eating miso soup. (16)<br />

Graph <strong>of</strong> changes in blood pressure by oral administration<br />

<strong>of</strong> miso (soybean paste) extracts. (17) Graph <strong>of</strong> reaction<br />

between coloring degree <strong>of</strong> miso <strong>and</strong> its antioxidative<br />

activity. Address: Dep. <strong>of</strong> Physiological Chemistry,<br />

Kurashiki Univ. <strong>of</strong> Science <strong>and</strong> the Arts, Kurashiki, Japan.<br />

1845. Wang, Yi-Chieh; Yu, R.C.; Chou, C.C. 2006.<br />

Antioxidative activities <strong>of</strong> soymilk fermented with lactic acid<br />

bacteria <strong>and</strong> bifi dobacteria. Food Microbiology 23:128-35.<br />

[34 ref]<br />

• Summary: Probiotics can serve as antioxidants. “Previous<br />

research has demonstrated that the antioxidative activity<br />

fermented soyfoods such as miso, natto, <strong>and</strong> tempeh, was<br />

remarkably stronger” than that <strong>of</strong> unfermented steamed<br />

© Copyright Soyinfo <strong>Center</strong> <strong>2012</strong><br />

HISTORY OF NATTO AND ITS RELATIVES 562<br />

soybeans,<br />

To develop a probiotic dietary adjunct / supplement,<br />

soymilk was fermented with two different lactic acid<br />

bacteria: (1) Lactobacillus acidophilus CCRC 14079, or (2)<br />

Streptococcus thermophilus CCRC 14085. And with two<br />

bifi dobacteria: (3) Bifi dobacterium infantis CCRC 14633, or<br />

Bifi dobacterium longum B6–individually <strong>and</strong> in conjunction<br />

(all together). Several antioxidative activities were<br />

investigated: The inhibition <strong>of</strong> ascorbate autoxidation. The<br />

scavenging effect <strong>of</strong> superoxide anion radicals <strong>and</strong> hydrogen<br />

peroxide, <strong>and</strong> the reducing activity exerted by different<br />

varieties <strong>of</strong> fermented soymilk. In addition, the effects <strong>of</strong><br />

freeze-drying <strong>and</strong> spray drying were also investigated.<br />

“In general, antioxidative activity in soymilk fermented<br />

with lactic acid bacteria <strong>and</strong> bifi dobacteria simultaneously is<br />

signifi cantly higher (P

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