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Sickle-Cell Policy<br />

PURPOSE: The following policy regarding athletes with the Sickle Cell Trait and the<br />

assessment and management as well as return to play guidelines has been developed in<br />

accordance with the University <strong>of</strong> North Carolina <strong>Wilmington</strong> Department <strong>of</strong> Athletic<br />

Training’s Mission Statement to provide quality healthcare services and assure the wellbeing<br />

<strong>of</strong> each student-athlete at <strong>UNC</strong>W. This policy is based on the National Athletic<br />

Trainers’ Association Consensus Statement regarding Sickle Cell Trait and the Athlete<br />

which can be found at: http://www.nata.org/statements/consensus/sicklecell.pdf.<br />

SICKLE CELL TRAIT DEFINITION:<br />

Sickle cell trait is the inheritance <strong>of</strong> one gene for sickle hemoglobin and one for normal<br />

hemoglobin. During intense or extensive exertion, the sickle hemoglobin can change the<br />

shape <strong>of</strong> red blood cells from round to crescent-shaped. This “sickling” <strong>of</strong> the red blood cells<br />

may put our student-athletes in great danger during intense exercise. Under unusual<br />

circumstances, serious morbidity and mortality resulting from complications in the collegiate<br />

student-athlete might include: infarction <strong>of</strong> the spleen with hypoxia or exercise, exertional<br />

heat illness such as exertional rhabdomyolysis (due to muscle break-down), heat stroke,<br />

renal failure, or sudden death syndrome. Hypoxia (seen in high altitude training with poor<br />

conditioning or combined with asthma), acidosis, dehydration, hyperthermia, or hypothermia<br />

can trigger shape changes <strong>of</strong> red blood cells that may precipitate vaso‐occlusive<br />

complications.<br />

Sickle cell anemia is more commonly found in the African American (1 out 12), Middle<br />

Eastern, and Central and South American populations compared to the Caucasian population<br />

(1out <strong>of</strong> 2,000 – 10,000). Currently, the U.S. Department <strong>of</strong> Health & Human Services<br />

requires mandatory testing for ALL newborns to test if the trait is present. This complication<br />

may result in a decrease amount <strong>of</strong> oxygen supply to the tissues <strong>of</strong> the body. There are NOT<br />

any restrictions to athletic participation, but recommendations by the National Athletic<br />

Trainer’s Association have been proposed during exertional exercise for those individuals<br />

with sickle-cell trait. Although the consequences can be severe sufficient rest, hydration, and<br />

cooling may be the treatment required to prevent most cases <strong>of</strong> “exertional sickling”.<br />

Signs <strong>of</strong> a Sickle Cell Crisis<br />

Sickling collapse can be mistaken for cardiac collapse or heat collapse. However, unlike<br />

sickling collapse, cardiac collapse tends to be “instantaneous’ (see sudden cardiac arrest<br />

policy), has no “cramping” with it, and the athlete (with ventricular fibrillation) who hits<br />

the ground no longer talks. Unlike heat collapse, sickling collapse <strong>of</strong>ten occurs within<br />

the first half hour onfield, as during initial sprints. Core temperature is not greatly<br />

elevated.<br />

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