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Therapies for Children With Autism Spectrum Disorders

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quotient (nonverbal mental age equivalent/chronological age X 100) took place in schools with<br />

children videotaped and language outcomes codes by non-masked assessors. Videotaping took<br />

place during snack sessions, selected because they are time limited and structured to include<br />

requesting and other social communication.<br />

The use of PECS in treatment classrooms was substantially increased immediately after<br />

training, with children in the PECS training classrooms having 3.90 times (95 percent CI: 1.75–<br />

8.68) the odds of being in a higher PECS use category than those whose teachers received no<br />

PECS training. The effect, however, was not maintained, and by Time 3, the immediate<br />

treatment group children were no more likely to be in a higher PECS rate category than untreated<br />

children (OR 1.10; 95 percent CI: 0.46–2.62).<br />

The third trial available on language intervention was also on PECS and was a<br />

nonrandomized controlled trial, with selection into or out of treatment based on a geographical<br />

limit. This study was reported in two papers. 262,265 Intervention was provided to 24 children<br />

whose special education classrooms were within 50 miles of the researchers; while a comparison<br />

group was selected from special education classrooms outside the 50-mile limit. <strong>Children</strong> were<br />

between 3 and 7 years old, with a diagnosis of Autistic Disorder. Diagnosis was clinically based,<br />

and not independently confirmed by the investigators. <strong>Children</strong> in the study were to have<br />

received no PECS training prior to the research.<br />

<strong>Children</strong> in the intervention group received a total of 15 hours of PECS teaching during<br />

various classroom activities over 4 to 5 weeks. The research team designed the instrument by<br />

which they assessed communicative interactions. They did not validate the instrument. The<br />

investigators followed the Bondy and Frost guidance 82 <strong>for</strong> using PECS in the classroom, but at<br />

Phase III randomly assigned children to either the approach specified in the PECS manual, or a<br />

modified PECS teaching procedure. 265<br />

Observation occurred 6 weeks prior to commencement of PECS intervention, 1 week prior to<br />

intervention and during the week immediately following completion of the 15 hours of PECS.<br />

The authors contended that the differences observed between the first and second observation<br />

periods (during which no intervention took place) would provide a measure of rate of maturation<br />

that could be used to differentiate maturation from treatment effects after the intervention phase;<br />

however, no evidence that this approach is valid was provided in the paper.<br />

No differences were observed on child-initiated communication either between the two preintervention<br />

measurement periods or between the two groups immediately prior to intervention.<br />

After intervention, however, the children in the PECS manual group had a significant increase in<br />

initiations, while the children in the control group had no increase, and the frequency of child to<br />

adult initiations was higher overall in the PECS manual group. Total adult-to-child initiations<br />

with the opportunity <strong>for</strong> child response showed an opposite response, with no significant increase<br />

in the PECS manual group, but a significant increase in the control group.<br />

Because the study only measured outcomes immediately after intervention in the classroom<br />

setting (at 6 weeks), it is impossible to determine whether the outcomes have any durability or to<br />

assess the effects outside of the classroom. Furthermore, although reliability of the observations<br />

was reported to be high (89.78 percent agreement), it was measured in only 56 percent of<br />

observation sessions, and the observers were not blinded to intervention status.<br />

Sensory- and Auditory-Focused Interventions<br />

Sensory integration, a specialized occupational therapy model based on the premise that the<br />

brain’s response to basic sensory input must be normalized be<strong>for</strong>e higher-order processes can be<br />

80

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