Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion
Description Intervention
Speech therapy: 4/15 (26)
N at enrollment:
G1: 8
G2: 7
N at follow-up:
G1: 13*
G2: 7
Criteria/Population
C-251
Baseline
Measures Outcomes
Factor scale (factors G1: -5.4
1-8):
G2: 2.7
G1: 8.5
G1/G2: P = 0.01
G2: 8.7
Processing (items
A-F):
G1: -2.4
G2: 1
G1/G2: P = 0.01
Modulation (items
G-K):
G1: -1.9
G2: 1
G1/G2: P = 0.02
Behavioral/emotional
abnormality
(items L-N):
G1: -1.1
G2: 0.7
G1/G2: P = 0.02
Factor scale
(factors 1-8):
G1: -3.1
G2: 1.4
G1/G2: P = 0.02
Medical:
Improvement in
bowel and sleep
abnormalities, n:
G1: 8/8
G2: 0
Harms:
NR
Modifiers:
NR
Comments: *The authors state that because the treatment was beneficial, after the RCT phase the 7 controls were offered the
treatment. One child could not participate because of his mother’s severe health problems, and one child began treatment but
moved from the area after completing only 9 weeks. The pre- and post-treatment measures of 5 controls in the continuation
phase are included in the baseline and outcome measures reported (the authors do not report the measures separately for the
original treatment group and continuation group).
** The authors do not report standard deviations or standard errors, but do report the Kruskal Wallace H statistic.