Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Tsang et al., 2007
Ratio of mental retardation: HKBABS total Educational/
(continued)
limited intelligence or score, mean ± SD: cognitive/
above:
Communication: academic
G1: 14:4
G1: 20.56 ± 9.40 attainment:
G2: 7:9
G2: 66.62 ± 30.92 Cognitive
Adaptive behavior: performance:
HKBABS total 6 months:
score, mean ± SD: G1: 7.00 ± 3.16
Daily living skills: G2: 13.19 ± 8.96
G1: 42.33 ± 12.89 G1/BL: P ≤ 0.01
G2: 62.62 ± 24.42 G2/BL: P = NS
Motor skills: G1/G2: P = NS*
CPEP-R score, 12 months:
mean ± SD: G1: 8.28 ± 4.04
Fine motor: G1/6M: P = NS
G1: 8.89 ± 1.97 ANOVA: time
G2: 9.50 ± 4.87 (P ≤ 0.001)
Gross motor: Cognitive verbal:
G1: 13.22 ± 2.88 6 months:
G2: 12.87 ± 5.51 G1: 3.50 ± 3.15
Eye-hand
G2: 11.12 ± 8.27
coordination: G1/BL: P ≤ 0.001
G1: 5.50 ± 2.20 G2/BL: P = NS
G2: 7.06 ± 4.65 G1/G2: P = NS*
12 months:
HKBABS total G1: 5.00 ± 4.42
score, mean ± SD: G1/6M: P ≤ 0.01
Motor skills: ANOVA: time
G1: 49.89 ± 11.86 (P ≤ 0.001)
G2: 61.50 ± 12.20 Developmental
scale total:
6 months:
G1: 56.89 ± 15.66
G2: 87.25 ± 30.68
G1/BL: P ≤ 0.001
G2/BL: P ≤ 0.001
G1/G2: P = NS*
12 months:
G1: 62.39 ± 17.80
G1/6M: P ≤ 0.05
ANOVA: time
(P ≤ 0.001)
Social skills:
HKBABS total
score, mean ±
SD:
Socialization:
6 months:
G1: 29.61 ± 8.26
G2: 58.44 ± 19.10
G1/BL: P = NS
G2/BL: P ≤ 0.01
G1/G2: P = NS*
Tsang et al., 2007
12 months:
(continued)
G1: 35.33 ± 12.09
G1/6M: P ≤ 0.01
ANOVA: time
C-257