Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Author:
Intervention:
Inclusion criteria: Social skills: Social skills:
Mahoney et al., Relationship-Focused • Children with either PDD Socio-emotional Socio-emotional
2005
(RF) intervention using /other developmental Functioning: Functioning:
Country: Responsive Teaching disabilities (DD) with age ITSEA, mean ± SD: ITSEA, mean ±
US
(RT) curriculum
ranging from 12-54
SD:
Weekly 1 hr parent-child months
Internalizing: Internalizing:
Practice
setting:
Academic
sessions for 1 year
Assessments:
• Meeting the DSM-IV
criteria for PDD
Exclusion criteria:
G1: 49.5 ± 8.1
Externalizing:
G1: 52.9 ± 8.8
P < 0.05
Intervention
Child & family data See inclusion criteria G1: 47.9 ± 8.6
collected at the beginning Age, mean/months ± SD:
Externalizing:
G1:49 ± 9
setting:
& end of intervention. G1: 32.4 ± 7.3
Self-regulation:
Home or Center- Trans-disciplinary Play- Mental age:
G1: 41.3 ± 8.6 Self-regulation:
based
Enrollment
Based assessment,
ITSEA to assess socio-
NR
Gender:
G1: 47.2 ± 7.8
Social competence:
period:
emotional behavior and M, %:
G1: 30.2 ± 15.8 Social
NR
TABS for problem G1: 65
competence:
Funding:
NR
behavior.
Both parents responded
F, %:
G1: 35
Communication/
language:
G1: 36.6 ± 11.4
Author industry to instruments.
Trans-disciplinary Communication/
relationship CBRS to rate child’s Race/ethnicity, %: Play-Based language:
disclosures: Pivotal behavior and White:
Assessment, mean Trans-disciplinary
NR
MBRS to assess parents’ G1: 95.2
± SD:
Play-Based
Design: style of interaction.
Object relations: Assessment,
Prospective case
G1: 16.5 ± 6.0 mean ± SD:
series
Expected:
Symbolic behavior: Object relations:
G1: 15.2 ± 5.3 G1: 22.1 ± 7.4
Groups:
G1: pervasive
development disorder –
not otherwise specified
Provider:
Early intervention
specialists
Children received RT on
an average of 32.6 ± 12.9
sessions
Hours/week of
intervention activities at
home:
15.1± 2.4
Measure of treatment
fidelity reported:
No
Co-interventions held
stable during treatment:
NR
Concomitant therapies:
NR
N at enrollment:
G1: 20
SES:
Education, mean/yrs ± SD :
Maternal:
G1: 15.5 ± 2.6
Paternal:
G1: 15.9 ± 2.6
Married, n (%):
G1: 20 (100)
Employment, %:
Employed:
G1: 52.1
Part time:
G1: 28.6
Full time:
G1: 23.8
Household income: NR
Diagnostic approach:
In Study: Diagnosed by
physicians
Diagnostic tool/method:
DSM-IV
C-313
Expressive
language:
G1: 13.8 ± 6.7
Receptive language:
G1: 12.1 ± 7.2
Problem behavior:
Temperament
Atypical Behavior
Scale (TABS) mean
± SD:
Detached:
G1: 21 ± 21.1
Hypersensitivity/hyp
eractivity :
G1: 39.7 ± 15.0
Under reactivity:
G1: 34.7 ± 16.3
Self-regulation:
G1: 33.8 ± 16.3
Overall:
G1: 55.1 ± 37.3
Symbolic
behavior:
G1: 20.3 ± 6.6
Expressive
language:
G1: 18.4 ± 8.6
Receptive
language:
G1:16.1 ± 9.1
Observed:
Object relations:
G1: 27.5 ± 8.2
PCI: G1: 2.2
Symbolic
behavior:
G1: 24.9 ± 10.0
PCI: G1: 2.03
Expressive
language:
G1: 24.1 ± 10.2
PCI: G1: 3.36