Therapies for Children With Autism Spectrum Disorders

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3157. Simpson RL, McKee M, Teeter D, et al. Evidence-Based Methods for Children and Youth with Autism Spectrum Disorders: Stakeholder Issues and Perspectives. Exceptionality. 2007 Nov;15(4):203-217. X-1, X-2, X-3, X-4 3158. Simpson RL and Myles BS. Effectiveness of facilitated communication with children and youth with autism. The Journal of Special Education. 1995 Win;28(4):424-439. X-10 3159. Singh I. Prolonged oculogyric crisis on addition of nifedipine to neuroleptic medication regime. British Journal of Psychiatry. 1987 Jan;150:127-128. X-1, X-3, X-10 3160. Singh J, Illes J, Lazzeroni L, et al. Trends in US autism research funding. J Autism Dev Disord. 2009 May;39(5):788-95. X-1, X-2, X-3, X-4 3161. Singh NN, Lancioni GE, Winton AS, et al. Mindful parenting decreases aggression and increases social behavior in children with developmental disabilities. Behav Modif. 2007 Nov;31(6):749-71. X-1, X-3, X-4 3162. Singh NN, Lancioni GE, Winton ASW, et al. Mindful Parenting Decreases Aggression, Noncompliance, and Self-Injury in Children with Autism. Journal of Emotional and Behavioral Disorders. 2006 Fall;14(3):169-177. X-1, X-3, X-4 3163. Singh VK and Jensen RL. Elevated levels of measles antibodies in children with autism. Pediatr Neurol. 2003 Apr;28(4):292-4. X-4 3164. Sinha Y, Silove N, Wheeler D, et al. Auditory integration training and other sound therapies for autism spectrum disorders. Cochrane Database Syst Rev. 2004(1):CD003681. X-2 3165. Sinha Y, Silove N, Wheeler D, et al. Auditory integration training and other sound therapies for autism spectrum disorders: a systematic review. Arch Dis Child. 2006 Dec;91(12):1018-22. X-2 3166. Sjogreen L, Andersson-Norinder J and Jacobsson C. Development of speech, feeding, eating, and facial expression in Mobius sequence. Int J Pediatr Otorhinolaryngol. 2001 Sep 28;60(3):197-204. X-1, X-4 3167. Sloan JL and Marcus L. Some findings on the use of the adaptive behavior scale with autistic children. J Autism Dev Disord. 1981 Jun;11(2):191-9. X-1, X-2, X-3, X-4, X-10 3168. Slotnick CF. Cognitive differences in classification tasks among autistic children. New Dir Child Dev. 1988 Spring(39):75-90. X-10 3169. Smith A, McCann R and McKinlay I. Second dose of MMR vaccine: health professionals’ level of confidence in the vaccine and attitudes towards the second dose. Commun Dis Public Health. 2001 Dec;4(4):273-7. X-1, X-4 3170. Smith A, Yarwood J and Salisbury DM. Tracking mothers’ attitudes to MMR immunisation 1996-2006. Vaccine. 2007 May 16;25(20):3996-4002. X-1, X-4 3171. Smith AE and Camarata S. Using teacher-implemented instruction to increase language intelligibility of children with autism. Journal of Positive Behavior Interventions. 1999 Sum;1(3):141-151. X-10 3172. Smith B, Chung MC and Vostanis P. The path to care in autism: is it better now? J Autism Dev Disord. 1994 Oct;24(5):551-63. X-1, X-4, X-10 D-220
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Comparative Effectiveness Review Nu
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This report is based on research co
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Acknowledgments We are indebted to
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Therapies for Children With Autism
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Dietary and Other Medical Intervent
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Figures Figure A. Analytic framewor
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Table A. Description of interventio
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Analytic Framework Figure A. Analyt
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Strength of evidence. The degree of
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epetitive behavior showed improveme
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subgroups of children, although the
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We encourage investigators to provi
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9. Remington B, Hastings RP, Kovsho
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46. Green J, Charman T, McConachie
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82. Reaven JA, Blakeley-Smith A, Ni
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120. Masi G, Cosenza A, Mucci M, et
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157. Evangeliou A, Vlachonikolis I,
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Introduction Need for Evidence for
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Interventions intended primarily to
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Table 1. Description of behavioral
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Serotonin reuptake inhibitors. Sero
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Table 3. Description of medical and
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Table 4. Description of allied heal
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Key Questions and Analytic Framewor
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Chapter 4 discusses the results in
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Methods This chapter documents proc
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• Did not present aggregated resu
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Additional behavioral interventions
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1. Did the study employ a group des
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Scoring: Studies minimally had to h
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These ratings of applicability do n
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Figure 2. Disposition of articles a
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• ABA-based approaches including
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education, children in the intensiv
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abilities. This finding is further
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Table 10. Outcomes of early intensi
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forecast behavior; perspective taki
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interaction with peers; outcome mea
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hyperactivity, inattention, challen
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Table 12. Outcomes of RCTs assessin
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Schedule for Affective Disorders an
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SCAS-P=Spence Child Anxiety Scale-P
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Summary of the literature. Jarusiew
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Table 14. Overview of educational s
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on the Ankara Developmental Screeni
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Checklist scores decreased by 8.4 f
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Table 15. Outcomes of studies asses
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evaluated the effects of risperidon
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that this somnolence improved over
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Table 17. Outcomes of RCTs of antip
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Serotonin Reuptake Inhibitors SRIs
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One prospective case series of esci
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Most participants were recruited fr
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Dietary and Other Medical Intervent
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Summary of the literature-other int
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withdrew after the first six weeks;
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therefore described separately belo
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addressed, 85 typically involves on
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In the second paper, 89 treatment s
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Table 25. Overview of CAM studies a
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Teacher and Parent Scales, behavior
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Because of the potentially increase
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Educational Interventions Child cha
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showed diminished response to escit
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oom as the other assessments, so it
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contrast group (n=18) on three meas
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and are based on consideration of f
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Few studies directly comparing the
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Strength of evidence. The strength
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While individual studies of CBT and
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Table 32. Summary of results of edu
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Table 33. Summary of results of med
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strength of this reviewed literatur
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Table 36. Intervention, strength of
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Table 37. Interventions/outcomes wi
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gains. 104 Other studies have seen
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percent of behavioral studies repor
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limited followup, lack of comparati
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individual intervention is warrante
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selecting participants for their st
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studies lacked an arm that consider
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23. Kanner L. Autistic Disturbances
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62. Dosman CF, Drmic IE, Brian JA,
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104. Ben-Itzchak E and Zachor DA. T
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142. Tyminski RF and Moore PJ. The
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177. Aman MG, McDougle CJ, Scahill
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214. Correia CT, Almeida JP, Santos
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252. Akhondzadeh S, Tajdar H, Moham
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290. Dawson G, Rogers S, Munson J,
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Acronyms/Abbreviations ABA Applied
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Appendix A. Exact Search Strings an
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Table A2. PsycINFO search strategie
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Therapies for Children with Autism
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Therapies for Children with ASD Sys
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Appendix C. Evidence Tables Tables
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Evidence Table. Therapies for child
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Country: US Practice setting: Clini
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Dunn-Geier et al., 2000 (continued)
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Evidence Table: Therapies for Child
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Appendix D. List of Excluded Studie
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31. Aarsland D, Cummings JL and Lar
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59. Ahearn WH, Clark KM, Gardenier
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89. Allison DB, Basile VC and MacDo
Page 615 and 616:
118. Ando H, Yoshimura I and Wakaba
Page 617 and 618:
146. Atkinson RP, Jenson WR, Rovner
Page 619 and 620:
177. Bakare MO, Agomoh AO, Ebigbo P
Page 621 and 622:
204. Baron-Cohen S, Scott FJ, Allis
Page 623 and 624:
233. Bebko JM, Perry A and Bryson S
Page 625 and 626:
262. Bergmann F, Stepp H, Metzger R
Page 627 and 628:
291. Birkan B, McClannahan LE and K
Page 629 and 630:
319. Boddy F, Rowan EN, Lett D, et
Page 631 and 632:
348. Bouma R and Schweitzer R. The
Page 633 and 634:
376. Broadstock M, Doughty C and Eg
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404. Brudnak MA. Application of gen
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432. Buitelaar JK. Why have drug tr
Page 639 and 640:
460. Butler DE, Nordin IC, L’Ital
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489. Campbell M, Locascio JJ, Choro
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517. Caronna EB, Augustyn M and Zuc
Page 645 and 646:
546. Case-Smith J and Miller H. Occ
Page 647 and 648:
574. Charlop MH, Burgio LD, Iwata B
Page 649 and 650:
602. Cheng CW, Cho SH, Taylor M, et
Page 651 and 652:
631. Cicero FR and Pfadt A. Investi
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662. Collier D and Reid G. A compar
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691. Coskun M, Karakoc S, Kircelli
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718. Cullen LA, Barlow JH and Cushw
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748. Davidovitch M, Holtzman G and
Page 661 and 662:
777. DeLeon IG, Fisher WW and Marhe
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805. Devlin SD, Harber MM. Collabor
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834. Doherty K, Fitzgerald M and Ma
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863. Dudley LL, Johnson C and Barne
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893. Dybvik AC. Autism and the Incl
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924. Elder JH. In-home communicatio
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953. Erickson CA, Posey DJ, Stigler
Page 675 and 676:
979. Faja S, Aylward E, Bernier R,
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1008. Ferri R, Elia M, Agarwal N, e
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1037. Fisher W, Kerbeshian J and Bu
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1066. Fragala-Pinkham M, Haley SM a
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1095. Furneaux B. Keeping the balan
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1124. Garcaa-Villamisar D, Wehman P
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1152. Ghezzi PM. Discrete Trials Te
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1180. Goin-Kochel RP, Myers BJ and
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1210. Gordon R, Handleman JS and Ha
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1239. Grimaldi BL. The central role
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1268. Guptill JT, Booker AB, Gibbs
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1296. Hamdan-Allen G. Brief report:
Page 699 and 700:
1324. Hare DJ, Jones JPR and Paine
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1356. Harrison S and Berry L. Valui
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1386. Heilbrun AB, Jr., Blum N and
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1414. Hetzroni OE and Shalem U. Fro
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1443. Holburn CS. Counter the mistr
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1473. Horner RH, Carr EG, Strain PS
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1504. Hughes C, Soares-Boucaud I, H
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1533. Ijichi S and Ijichi N. Beyond
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1562. James SJ, Cutler P, Melnyk S,
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1591. Johnson CR, Butter EM, Handen
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1619. Joyce PR. The medical model-w
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1647. Karmali I, Greer RD, Nuzzolo-
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1673. Kelly AB, Garnett MS, Attwood
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1702. Kielinen M, Linna SL and Moil
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1731. Klin A, Lin DJ, Gorrindo P, e
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1761. Koegel RL and Frea WD. Treatm
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1790. Kolmen BK, Feldman HM, Handen
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1819. Kratochvil CJ, Findling RL, M
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1846. Lam MK and Rao N. Developing
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1874. Lattimore LP, Parsons MB and
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1903. Lee PC. Verification of a sim
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1932. Lerman DC, Vorndran C, Addiso
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1960. Licciardello CC, Harchik AE a
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1989. Liptak GS, Orlando M, Yinglin
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2015. Lorimer PA, Simpson RL, Myles
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2043. Luiselli JK, Kane A, Treml T,
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2071. MacFarlane JR and Kanaya T. W
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2099. Malone RP, Maislin G, Choudhu
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2127. Marin FZ. CAM versus nucleopl
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2157. Martineau J, Roux S, Adrien J
Page 759 and 760:
2185. Matson JL and Lo Vullo SV. A
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2213. McCabe H. The Importance of P
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2240. McDougle CJ, Holmes JP, Carls
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2267. McHale SM, Olley JG, Marcus L
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2296. Merlo LJ, Lehmkuhl HD, Geffke
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2325. Minderaa RB, Anderson GM, Vol
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2354. Montgomery JM, Duncan CR and
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2385. Morrison RS, Sainato DM, Benc
Page 775 and 776: 2413. Munesue T, Ono Y, Mutoh K, et
Page 777 and 778: 2445. Napolitano DA, Tessing JL, Mc
Page 779 and 780: 2474. Niederhofer H and Pittschiele
Page 781 and 782: 2501. Nwora AJ and Gee BM. A case s
Page 783 and 784: 2530. Olive ML, Lang RB and Davis T
Page 785 and 786: 2559. Owens JA, Rosen CL and Mindel
Page 787 and 788: 2589. Pansegrouw I and Alant E. Com
Page 789 and 790: 2618. Paul C, Williams KE, Riegel K
Page 791 and 792: 2646. Perry R, Nobler MS and Campbe
Page 793 and 794: 2675. Piazza CC, Hagopian LP, Hughe
Page 795 and 796: 2704. Poon L, Partika N and Bolman
Page 797 and 798: 2734. Prizant BM. Speech-language p
Page 799 and 800: 2764. Rapp JT, Vollmer TR, St. Pete
Page 801 and 802: 2792. Reed P, Broomfield L, McHugh
Page 803 and 804: 2819. Remington G, Sloman L, Konsta
Page 805 and 806: 2849. Ringdahl JE, Kitsukawa K, And
Page 807 and 808: 2877. Rogers SJ. Interventions that
Page 809 and 810: 2908. Rossignol DA. Novel and emerg
Page 811 and 812: 2939. Rutter M, Kreppner J, Croft C
Page 813 and 814: 2967. Sandt D. Social Stories for S
Page 815 and 816: 2994. Scanlon K. Art therapy with a
Page 817 and 818: 3023. Schneider CK, Melmed RD, Bars
Page 819 and 820: 3054. Schwartz IS, Sandall SR, Garf
Page 821 and 822: 3085. Shafer MS, Egel AL and Neef N
Page 823 and 824: 3115. Shipley-Benamou R, Lutzker JR
Page 825: 3143. Siller M and Sigman M. The be
Page 829 and 830: 3202. Snyder A, Bossomaier T and Mi
Page 831 and 832: 3230. Spero MH. The emancipation of
Page 833 and 834: 3259. Stephens CE. Spontaneous imit
Page 835 and 836: 3289. Strambi M, Longini M, Hayek J
Page 837 and 838: 3318. Suzumura K. How an autistic b
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Page 851 and 852: 3522. Vitiello B. Recent NIMH clini
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Page 869 and 870: Appendix F. Approach to Categorizin
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Yes—no disclosures to make G7 Bai
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Table G1. Characteristics of recent
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Random assignment Appropriate compa
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Study Group design Random assignmen
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APPENDIX I. Applicability Summary T
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Social skills (continued) Domain De
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Therapies for Children With Autism Spectrum Disorders

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