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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD<br />

Study<br />

Inclusion/Exclusion Baseline<br />

Description Intervention<br />

Criteria/Population Measures Outcomes<br />

Author:<br />

Intervention:<br />

Inclusion criteria: Language/ Language/<br />

Keen et al., Stronger Families Project • Recruited from commu- communication: communication:<br />

2007<br />

Intervention: A two day nity health, hospital, and CSBS score, CSBS score,<br />

Country: parent workshop, followed education-based early median (range): median (range):<br />

Australia by 10 sessions of<br />

intervention services Total:<br />

Total:<br />

Practice<br />

setting:<br />

Academic<br />

Intervention<br />

individual home-based • Clinical diagnosis of G1: 74.5 (65-126)<br />

early intervention, using a autism based on DSM-IV Social:<br />

social-pragmatic<br />

criteria<br />

G1: 4 (3-11)<br />

approach emphasizing Exclusion criteria: Speech:<br />

G1: 75 (65-135)<br />

G1/BL: P = 0.1<br />

Social:<br />

G1: 5 (3-15)<br />

setting:<br />

Clinic, Home<br />

Enrollment<br />

period:<br />

NR<br />

Funding:<br />

NR<br />

Author industry<br />

relationship<br />

disclosures:<br />

NR<br />

Design:<br />

Case series,<br />

prospective<br />

Note:<br />

For more details<br />

on the Stronger<br />

Families Project<br />

intervention, see<br />

Rodger et al.,<br />

2004<br />

functional use of • See inclusion criteria<br />

communication skills in Age, months ± SD<br />

natural and semi- (range):<br />

structured interactions; 38.06 ± 5.49 (25-47)<br />

6 week intervention Mental age:<br />

Assessments:<br />

NR<br />

Scales of Independent Gender, n (%):<br />

Behavior, CSBS admini- Male: 14 (87)<br />

stered by observer in Female: 2 (13)<br />

clinic. Parents completed Race/ethnicity:<br />

parental stress and NR<br />

component measures. SES:<br />

Groups:<br />

Maternal education: NR<br />

G1: intervention Household income: NR<br />

Provider:<br />

Diagnostic approach:<br />

NR<br />

Referral<br />

Measure of treatment Diagnostic tool/method:<br />

fidelity reported: DSM-IV<br />

No<br />

Diagnostic category:<br />

Co-interventions held NR<br />

stable during treatment: Other characteristics:<br />

NR<br />

NR<br />

Concomitant therapies:<br />

G1: 9 (3-17) G1/BL: P = 0.122<br />

Symbolic:<br />

Speech:<br />

G1: 5.5 (3-13) G1: 8.5 (3-17)<br />

CSBS caregiver G1/BL: P = 0.194<br />

questionnaire score, Symbolic:<br />

median (range): G1: 6.5 (3-17)<br />

Total:<br />

G1/BL: P = 0.203<br />

G1: 84.5 (65-100) CSBS caregiver<br />

Social:<br />

questionnaire<br />

G1: 4 (3-7) score, median<br />

Speech:<br />

(range):<br />

G1: 10 (3-17) Total:<br />

Symbolic:<br />

G1: 90 (70-103)<br />

G1: 7.5 (3-10) G1/BL: P = 0.007<br />

Social:<br />

G1: 5.5 (3-9)<br />

G1/BL: P = 0.017<br />

Speech:<br />

G1: 10.5 (7-17)<br />

G1/BL: P = 0.044<br />

Symbolic:<br />

G1: 7 (5-11)<br />

G1/BL: P = 0.007<br />

NR<br />

Harms:<br />

N at enrollment:<br />

NR<br />

G1: 16<br />

Modifiers:<br />

N at follow-up:<br />

No significant<br />

G1: 16<br />

relationships<br />

found between<br />

child/parent<br />

variables and<br />

change in<br />

behavior sample<br />

scores<br />

C-223

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