Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Inclusion/ Exclusion Baseline
Description Intervention
Criteria/ Population Measures Outcomes
Omega-3 supplements: 8 Postcollege:
Separation: (0-10)
N at enrollment: G1: 3 (30)
Parent report: 54.5 G2: 6.50 ± 4.53
G1: 10
G2: 6 (26.1)
Child report: 51.6 (0-14)
G2: 23
Missing:
Social:
School anxiety:
N at follow-up:
G1: 0
Parent report: 51.5 G1: 2.83 ± 2.10
G1: 10
G2: 1 (4.3)
Child report: 45.2 (1-6)
G2: 21
Household income: NR School:
G2: 0.91 ± 0.03
Diagnostic approach: Parent report: 33.3 (0-2)
In Study
Child report: 41.9 Percentage of
Diagnostic tool/method: Total anxiety children in both
See inclusion criteria symptoms: groups obtaining
Diagnostic category, n Parent report: 66.7 SCARED scores
(%):
Child report: 51.6 within the clini-
Autism:
cally significant
G1: 3 (30)
range:**
G2: 12 (52.2)
Panic:
PDD-NOS:
Parent report: 16
G1: 2 (20)
Child report: 17.6
G2: 2 (8.7)
Generalized:
Aspergers:
Parent report: 8
G1: 5 (50)
G2: 9 (39.1)
Child report: 17.6
Reaven et al.,
Other characteristics, n
Separation:
2009 (continued)
(%):
Parent report: 24
Primary anxiety diagnosis:
Child report: 29.4
Generalized anxiety:
Social:
G1: 7 (70)
Parent report: 32
G2: 15 (65.2)
Child report: 47.1
Separation anxiety:
School:
G1: 2 (20)
Parent report: 16
G2: 4 (17.3)
Child report: 17.6
Social anxiety:
Total anxiety
G1: 1 (10)
symptoms:
G2: 4 (17.4)
Parent report: 28
Food allergies and
Child report: 41.2
restricted diet: 10 (31.2)
Harms:
NR
Modifiers:
NR
Comments: *1 child in G1 was placed on a different mood stabilizer and 2 children in G2 received higher doses of medicine
for attentional difficulties; data on changes in therapy not available for 13 participants.
**Chi-square analyses for the entire sample on pretreatment and post-treatment assessments indicated significant differences
in clinical classification for parent report (P = 0.03), but not for child report (P = 0.48).
Author:
Reed et al., 2009
Country:
US
Practice
setting:
Academic
Intervention
setting:
Clinic
Enrollment
period:
NR
Intervention:
Parent-based sleep
education workshops,
each workshop consisted
of 3 sessions conducted
over 3 consecutive
weeks, with each session
lasting 2 hours
Assessments:
Children’s Sleep Habits
Questionnaire, Family
Inventory of Sleep Habits,
Parental Concerns
Inclusion criteria:
• Families with children
between the ages of 3
and 10 years
• Child with clinical
diagnosis of ASD
• Families expressed that
sleep was a concern
Exclusion criteria:
• Primary sleep disorders
(e.g., sleep apnea,
narcolepsy)
C-89
Social skills:
PCQ social interactions
score, mean
± SD:
G1: 2.80 ± 0.95
Communication/
language:
PCQ language use/
understanding
score, mean ± SD:
G1: 3.00 ± 1.12
Repetitive
behavior:
Social skills:
PCQ social interactions
score,
mean ± SD:
G1: 2.55 ± 0.89
G1/BL: P = NS
Communication/
language:
PCQ language
use/understandding
score, mean
± SD:
G1: 2.85 ± 1.04