Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Magiati et al., Provider:
SES:
Communication/ Symbolic play test
2007 (continued) EIBI provider, n (%): Parental education, n: language:
score, develop-
Supervisor and
Higher (degree or above): EOWPVT-R score, mental age,
consultant: 14 (50) G1: 18
mean ± SD (range): months ± SD
Supervisor: 7 (25) G2: 7
G1: 2.2 ± 7.8 (0-39) (range):
Consultant: 3 (11) Lower (A-levels or below): G2: 1.7 ± 3.7 (0-12) G1: 29.2 ± 12.7
Senior therapist: 2 (7) G1: 5
G1/G2: P = NS (12-65)
One-two parents trained G2: 8
VABS communica- G2: 28.8 ± 13
as a therapist: 23 (82) No information:
tion, age equivalent, (12-61) (n=15)
Nursery provider, n (%): G1: 5
months ± SD G1/G2: P = NS
Teachers: 16 (100) G2: 1
(range):
BPVS score,
Measure of treatment Family SEC, n:
G1: 14.4 ± 5.2 mean ± SD
fidelity reported: Higher (categories 1–3): (8-28) (n=26) (range):
No
G1: 23
G2: 13.1 ± 4.5 G1: 20.8 ± 20.8
Co-interventions held G2: 9
(8-26) (n=14) (0-68) (n=27)
stable during treatment: Lower (categories 4–9): G1/G2: P = NS G2: 13.2 ± 17.8
NR
G1: 4
VABS communica- (0-52) (n=15)
Concomitant therapies, G2: 6
tion, standard score, G1/G2: P = NS
n:
No information:
mean ± SD (range): Communication/
Special Dietary: G1: 1
G1: 60 ± 7.4 (50-78) language:
G1: 21
G2: 1
(n=26)
EOWPVT-R
G2: 6
Diagnostic approach: G2: 55.8 ± 6.8 score, mean ± SD
G1/G2: P = 0.01 In Study
(47-74) (n=14) (range):
Other biological
Diagnostic tool/method: G1/G2: P = NS G1: 13 ± 17.3
interventions:
ADI-R
Adaptive behavior: (0-59) (n=27)
G1: 17
Diagnostic category, n (%): VABS daily living, G2: 10.2 ± 13.7
G2: 3
Autism:
age equivalent, (0-38) (n=15)
G1/G2: P = 0.01 G1: 19 (43)
months ± SD G1/G2: P = NS
Extra-curricular
G2: 13 (81)
(range):
VABS
educational interventions: ASD:
G1: 19 ± 6.1 (11-39) communication,
G1: 2
G1: 9 (20)
(n=26)
age equivalent,
G2: 7
G2: 3 (19)
G2: 20 ± 3.9 (15-27) months ± SD
G1/G2: P < 0.01
Other alternative
Other characteristics:
NR
(n=14)
G1/G2: P = NS
(range):
G1: 29.6 ± 17.2
treatments:
VABS daily living, (12-70)
G1: 8
standard score, G2: 23.6 ± 16.8
G2: 2
mean ± SD (range): (11-67)
G1/G2: P = 0.18
G1: 63 ± 7.4 (55-89) G1/G2: P = NS
N at enrollment:
(n=26)
VABS communi-
G1: 28
G2: 61.4 ± 4.9 cation, standard
G2: 16
(52-69) (n=14) score, mean ± SD
N at follow-up:
G1/G2: P = NS (range):
G1: 28
G2: 16
Social skills:
VABS socialization,
G1: 61.2 ± 17.6
(41-106)
age equivalent, G2: 51.6 ± 14.8
months ± SD (37-87)
(range):
G1: 13 ± 4.4 (6-24)
(n=26)
G2: 11.1 ± 3.4
(6-20) (n=14)
G1/G2: P = NS
G1/G2: P = NS
Magiati et al.,
VABS socialization, Adaptive
2007 (continued)
standard score, behavior:
mean ± SD (range): VABS daily living,
G1: 60.3 ± 6 (51-76) age equivalent,
(n=26)
months ± SD
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