Therapies for Children With Autism Spectrum Disorders

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1547. Israel ML, Connolly DA, von Heyn RE, et al. Teaching severely self-abusive and aggressive autistic residents to exit to fire alarms. J Behav Ther Exp Psychiatry. 1993 Dec;24(4):343-55. X-10 1548. Ivancic Jokic N, Majstorovic M, Bakarcic D, et al. Dental caries in disabled children. Coll Antropol. 2007 Mar;31(1):321-4. X-4 1549. Ivanov I, Klein M, Green WH, et al. The Challenges of Psychopharmacological Management of Children with Severe Developmental Disabilities. Journal of Child and Adolescent Psychopharmacology. 2006 Dec;16(6):793-799. X-3 1550. Ivey ML, Heflin LJ and Alberto P. The Use of Social Stories to Promote Independent Behaviors in Novel Events for Children with PDD-NOS. Focus on Autism and Other Developmental Disabilities. 2004 Fal;19(3):164-176. X-3 1551. JÃ¤rbrink K, McCrone P, Fombonne E, et al. Cost-impact of young adults with highfunctioning autistic spectrum disorder. Research in Developmental Disabilities. 2007 Jan- Feb;28(1):94-104. X-1, X-4 1552. Jackson C. A life of his own. Ment Health Care. 1998 Feb;1(6):186-7. X-10 1553. Jackson HJ. Current trends in the treatment of phobias in autistic and mentally retarded persons. Australia & New Zealand Journal of Developmental Disabilities. 1983 Dec;9(4):191-208. X-1, X-2, X-3, X-4, X-10 1554. Jacobson JW. Early intensive behavioral intervention: Emergence of a consumer-driven service model. The Behavior Analyst. 2000 Fal;23(2):149-171. X-1, X-2, X-3, X-4 1555. Jacobson JW and Ackerman LJ. Differences in adaptive functioning among people with autism or mental retardation. J Autism Dev Disord. 1990 Jun;20(2):205-19. X-4, X-10 1556. Jacobson L and Stenstrom I. Visually impairing ROP in children born in Sweden 1975-89. Acta Ophthalmol Suppl. 1993(210):16-9. X-1, X-4, X-10 1557. Jacquemont S, Hagerman RJ, Hagerman PJ, et al. Fragile-X syndrome and fragile Xassociated tremor/ataxia syndrome: two faces of FMR1. Lancet Neurol. 2007 Jan;6(1):45-55. X-1, X-2, X-3, X-4 1558. Jahr E. Teaching children with autism to answer novel wh-questions by utilizing a multiple exemplar strategy. Res Dev Disabil. 2001 Sep-Oct;22(5):407-23. X-3 1559. Jahr E, Eikeseth S, Eldevik S, et al. Frequency and Latency of Social Interaction in an Inclusive Kindergarten Setting: A Comparison between Typical Children and Children with Autism. Autism: The International Journal of Research and Practice. 2007;11(4):349-363. X-4 1560. Jahr E, Eldevik S and Eikeseth S. Teaching children with autism to initiate and sustain cooperative play. Res Dev Disabil. 2000 Mar-Apr;21(2):151-69. X-3 1561. Jambaque I, Chiron C, Dumas C, et al. Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. Epilepsy Res. 2000 Feb;38(2-3):151-60. X-1, X-4 D-108
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Comparative Effectiveness Review Nu
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This report is based on research co
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Acknowledgments We are indebted to
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Therapies for Children With Autism
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Dietary and Other Medical Intervent
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Figures Figure A. Analytic framewor
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Table A. Description of interventio
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Analytic Framework Figure A. Analyt
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Strength of evidence. The degree of
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epetitive behavior showed improveme
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subgroups of children, although the
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We encourage investigators to provi
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9. Remington B, Hastings RP, Kovsho
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46. Green J, Charman T, McConachie
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82. Reaven JA, Blakeley-Smith A, Ni
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120. Masi G, Cosenza A, Mucci M, et
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157. Evangeliou A, Vlachonikolis I,
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Introduction Need for Evidence for
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Interventions intended primarily to
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Table 1. Description of behavioral
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Serotonin reuptake inhibitors. Sero
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Table 3. Description of medical and
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Table 4. Description of allied heal
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Key Questions and Analytic Framewor
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Chapter 4 discusses the results in
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Methods This chapter documents proc
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• Did not present aggregated resu
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Additional behavioral interventions
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1. Did the study employ a group des
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Scoring: Studies minimally had to h
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These ratings of applicability do n
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Figure 2. Disposition of articles a
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• ABA-based approaches including
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education, children in the intensiv
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abilities. This finding is further
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Table 10. Outcomes of early intensi
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forecast behavior; perspective taki
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interaction with peers; outcome mea
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hyperactivity, inattention, challen
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Table 12. Outcomes of RCTs assessin
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Schedule for Affective Disorders an
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SCAS-P=Spence Child Anxiety Scale-P
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Summary of the literature. Jarusiew
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Table 14. Overview of educational s
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on the Ankara Developmental Screeni
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Checklist scores decreased by 8.4 f
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Table 15. Outcomes of studies asses
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evaluated the effects of risperidon
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that this somnolence improved over
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Table 17. Outcomes of RCTs of antip
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Serotonin Reuptake Inhibitors SRIs
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One prospective case series of esci
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Most participants were recruited fr
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Dietary and Other Medical Intervent
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Summary of the literature-other int
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withdrew after the first six weeks;
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therefore described separately belo
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addressed, 85 typically involves on
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In the second paper, 89 treatment s
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Table 25. Overview of CAM studies a
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Teacher and Parent Scales, behavior
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Because of the potentially increase
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Educational Interventions Child cha
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showed diminished response to escit
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oom as the other assessments, so it
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contrast group (n=18) on three meas
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and are based on consideration of f
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Few studies directly comparing the
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Strength of evidence. The strength
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While individual studies of CBT and
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Table 32. Summary of results of edu
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Table 33. Summary of results of med
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strength of this reviewed literatur
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Table 36. Intervention, strength of
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Table 37. Interventions/outcomes wi
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gains. 104 Other studies have seen
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percent of behavioral studies repor
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limited followup, lack of comparati
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individual intervention is warrante
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selecting participants for their st
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studies lacked an arm that consider
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23. Kanner L. Autistic Disturbances
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62. Dosman CF, Drmic IE, Brian JA,
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104. Ben-Itzchak E and Zachor DA. T
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142. Tyminski RF and Moore PJ. The
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177. Aman MG, McDougle CJ, Scahill
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214. Correia CT, Almeida JP, Santos
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252. Akhondzadeh S, Tajdar H, Moham
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290. Dawson G, Rogers S, Munson J,
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Acronyms/Abbreviations ABA Applied
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Appendix A. Exact Search Strings an
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Table A2. PsycINFO search strategie
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Therapies for Children with Autism
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Therapies for Children with ASD Sys
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Appendix C. Evidence Tables Tables
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Evidence Table. Therapies for child
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Country: US Practice setting: Clini
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Dunn-Geier et al., 2000 (continued)
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Evidence Table: Therapies for Child
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Appendix D. List of Excluded Studie
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31. Aarsland D, Cummings JL and Lar
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59. Ahearn WH, Clark KM, Gardenier
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89. Allison DB, Basile VC and MacDo
Page 615 and 616:
118. Ando H, Yoshimura I and Wakaba
Page 617 and 618:
146. Atkinson RP, Jenson WR, Rovner
Page 619 and 620:
177. Bakare MO, Agomoh AO, Ebigbo P
Page 621 and 622:
204. Baron-Cohen S, Scott FJ, Allis
Page 623 and 624:
233. Bebko JM, Perry A and Bryson S
Page 625 and 626:
262. Bergmann F, Stepp H, Metzger R
Page 627 and 628:
291. Birkan B, McClannahan LE and K
Page 629 and 630:
319. Boddy F, Rowan EN, Lett D, et
Page 631 and 632:
348. Bouma R and Schweitzer R. The
Page 633 and 634:
376. Broadstock M, Doughty C and Eg
Page 635 and 636:
404. Brudnak MA. Application of gen
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432. Buitelaar JK. Why have drug tr
Page 639 and 640:
460. Butler DE, Nordin IC, L’Ital
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489. Campbell M, Locascio JJ, Choro
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517. Caronna EB, Augustyn M and Zuc
Page 645 and 646:
546. Case-Smith J and Miller H. Occ
Page 647 and 648:
574. Charlop MH, Burgio LD, Iwata B
Page 649 and 650:
602. Cheng CW, Cho SH, Taylor M, et
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631. Cicero FR and Pfadt A. Investi
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662. Collier D and Reid G. A compar
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691. Coskun M, Karakoc S, Kircelli
Page 657 and 658:
718. Cullen LA, Barlow JH and Cushw
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748. Davidovitch M, Holtzman G and
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777. DeLeon IG, Fisher WW and Marhe
Page 663 and 664: 805. Devlin SD, Harber MM. Collabor
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Page 667 and 668: 863. Dudley LL, Johnson C and Barne
Page 669 and 670: 893. Dybvik AC. Autism and the Incl
Page 671 and 672: 924. Elder JH. In-home communicatio
Page 673 and 674: 953. Erickson CA, Posey DJ, Stigler
Page 675 and 676: 979. Faja S, Aylward E, Bernier R,
Page 677 and 678: 1008. Ferri R, Elia M, Agarwal N, e
Page 679 and 680: 1037. Fisher W, Kerbeshian J and Bu
Page 681 and 682: 1066. Fragala-Pinkham M, Haley SM a
Page 683 and 684: 1095. Furneaux B. Keeping the balan
Page 685 and 686: 1124. Garcaa-Villamisar D, Wehman P
Page 687 and 688: 1152. Ghezzi PM. Discrete Trials Te
Page 689 and 690: 1180. Goin-Kochel RP, Myers BJ and
Page 691 and 692: 1210. Gordon R, Handleman JS and Ha
Page 693 and 694: 1239. Grimaldi BL. The central role
Page 695 and 696: 1268. Guptill JT, Booker AB, Gibbs
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Page 699 and 700: 1324. Hare DJ, Jones JPR and Paine
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Page 723 and 724: 1673. Kelly AB, Garnett MS, Attwood
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Page 757 and 758: 2157. Martineau J, Roux S, Adrien J
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Page 761 and 762: 2213. McCabe H. The Importance of P
Page 763 and 764: 2240. McDougle CJ, Holmes JP, Carls
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2267. McHale SM, Olley JG, Marcus L
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2296. Merlo LJ, Lehmkuhl HD, Geffke
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2325. Minderaa RB, Anderson GM, Vol
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2354. Montgomery JM, Duncan CR and
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2385. Morrison RS, Sainato DM, Benc
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2413. Munesue T, Ono Y, Mutoh K, et
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2445. Napolitano DA, Tessing JL, Mc
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2474. Niederhofer H and Pittschiele
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2501. Nwora AJ and Gee BM. A case s
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2530. Olive ML, Lang RB and Davis T
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2559. Owens JA, Rosen CL and Mindel
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2589. Pansegrouw I and Alant E. Com
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2618. Paul C, Williams KE, Riegel K
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2646. Perry R, Nobler MS and Campbe
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2675. Piazza CC, Hagopian LP, Hughe
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2704. Poon L, Partika N and Bolman
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2734. Prizant BM. Speech-language p
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2764. Rapp JT, Vollmer TR, St. Pete
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2792. Reed P, Broomfield L, McHugh
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2819. Remington G, Sloman L, Konsta
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2849. Ringdahl JE, Kitsukawa K, And
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2877. Rogers SJ. Interventions that
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2908. Rossignol DA. Novel and emerg
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2939. Rutter M, Kreppner J, Croft C
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2967. Sandt D. Social Stories for S
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2994. Scanlon K. Art therapy with a
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3023. Schneider CK, Melmed RD, Bars
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3054. Schwartz IS, Sandall SR, Garf
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3085. Shafer MS, Egel AL and Neef N
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3115. Shipley-Benamou R, Lutzker JR
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3143. Siller M and Sigman M. The be
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3173. Smith C, Felce D, Jones E, et
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3202. Snyder A, Bossomaier T and Mi
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3230. Spero MH. The emancipation of
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3259. Stephens CE. Spontaneous imit
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3289. Strambi M, Longini M, Hayek J
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3318. Suzumura K. How an autistic b
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3346. Tager-Flusberg H and Calkins
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3376. Taylor I, O’Reilly M and La
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3407. Thunberg G, Ahlsen E and Sand
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3435. Trembath D, Balandin S, Toghe
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3464. Turner-Brown LM, Perry TD, Di
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3492. Van Der Putt R, Dineen C, Jan
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3522. Vitiello B. Recent NIMH clini
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3553. Walenski M, Mostofsky SH, Gid
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3581. Weber RC and Thorpe J. Teachi
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3610. Wheeler JJ, Baggett BA, Fox J
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3637. Williams B. Mental handicap n
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3669. Wimpory D, Chadwick P and Nas
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3698. Worth S and Reynolds S. The A
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3728. Young JM, Krantz PJ, McClanna
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3759. Zuddas A, Di Martino A, Mugli
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Appendix F. Approach to Categorizin
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APPENDIX G. Discussion of Recent Sy
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one a casein free regime. Diets wer
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outcome data as Type 6, defined as
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Yes—no disclosures to make G7 Bai
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Table G1. Characteristics of recent
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Random assignment Appropriate compa
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Study Group design Random assignmen
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APPENDIX I. Applicability Summary T
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Social skills (continued) Domain De
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Therapies for Children With Autism Spectrum Disorders

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