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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD<br />

Study<br />

Inclusion/Exclusion Baseline<br />

Description Intervention<br />

Criteria/Population Measures Outcomes<br />

Author:<br />

Intervention:<br />

Inclusion criteria: Motor skills: Motor skills:<br />

Carmody et al., 2 sets of eyeglasses with • <strong>Children</strong> consecutively Ball catch score, Ball catch score,<br />

2001<br />

prism lenses (5 diopters), referred to a child mean % ± SD: mean % ± SD:<br />

Country: 1 with lenses oriented development center and Habitual viewing: Facilitating<br />

Hong Kong prism base-up and the diagnosed with autistic 31.30 ± 22.53 lenses:<br />

other oriented prism base- disorder by DSM-IV or<br />

70.91 ± 24.94<br />

Practice down<br />

WHO criteria<br />

Ball misses, %: Habitual vs.<br />

setting:<br />

Exclusion criteria: Habitual viewing: 49 Facilitating<br />

Academic All children assessed • See inclusion criteria<br />

lenses, t(22) =<br />

without glasses (habitual Age, median years Ball passive catches 7.656,<br />

viewing) and with each of (range): 8 (3-18) (ball caught after P < 0.0001<br />

the two study eyeglasses Mental age:<br />

rebounding off<br />

(base-up viewing and NR<br />

child’s body), %: Ball misses, %:<br />

base-down viewing) Gender, n (%):<br />

Habitual viewing: 31 Facilitating<br />

M: 22 (91.7)<br />

lenses: 24<br />

Base-up, base-down F: 2 (8.3)<br />

Ball active catches<br />

ambient lenses trials <strong>for</strong><br />

(ball caught on Ball passive<br />

60-90 seconds/trial with a Race/ethnicity:<br />

swing without hitting catches (ball<br />

random order of lenses NR<br />

child first), %: caught after<br />

SES:<br />

Habitual viewing: 20 rebounding off<br />

child’s body), %:<br />

Maternal education: NR<br />

Facilitating<br />

lenses: 12<br />

Intervention<br />

setting: Child<br />

development<br />

center<br />

Enrollment<br />

period:<br />

July 1994 to<br />

December 1995<br />

Funding: Portion<br />

sponsored by<br />

NYU<br />

Author industry<br />

relationship<br />

disclosures:<br />

NR<br />

Design: Case<br />

series<br />

Carmody et al.,<br />

2001 (continued)<br />

Facilitating lenses: the<br />

prism eyeglasses that<br />

worked best <strong>for</strong> an<br />

individual patient<br />

Assessment: Each<br />

participant assessed<br />

independently by one<br />

experimenter in a single<br />

session lasting 20–30<br />

minutes. Behavior<br />

assessment done by<br />

raters, per<strong>for</strong>mance<br />

videotaped<br />

Groups:<br />

G1: all participants<br />

Provider:<br />

Optometrist or<br />

pediatrician<br />

Treatment manual<br />

followed: No<br />

Defined protocol<br />

followed: Yes<br />

Measure of treatment<br />

fidelity reported:<br />

No<br />

Co-interventions held<br />

stable during treatment:<br />

NA<br />

Concomitant therapies:<br />

NR<br />

Household income: NR<br />

Diagnostic approach:<br />

Referral<br />

Diagnostic tool/method:<br />

DSM-IV, WHO criteria<br />

Diagnostic category, n<br />

(%):<br />

Autistic disorder: 24 (100)<br />

Other characteristics, n:<br />

Normal visual acuity: 18<br />

Far-sighted: 3<br />

Near-sighted: 3<br />

C-389<br />

Ball active<br />

catches (ball<br />

caught on swing<br />

without hitting<br />

child first), %:<br />

Facilitating<br />

lenses: 64<br />

<strong>Children</strong>’s ability<br />

to catch a ball<br />

was significantly<br />

better with use of<br />

facilitating lenses<br />

as compared with<br />

habitual viewing<br />

(P < 0.0001)<br />

Harms<br />

NR<br />

Modifiers<br />

NR

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