Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Description Intervention
Green et al.
2010 (continued)
Green et al.
2010 (continued)
Concomitant therapies,
n (%):
Contact time with other
treatment professionals,
mean hours ± SD:
G1: 9.5 ± 16.3
G2: 9.8 ± 12.9
Group-based autism
psychoeducation, n (%):
G1: 28 (38)
G2: 34 (49)
Communication-focused
interventions, n (%):
G1: 27 (36)
G2: 23 (33)
Early intensive behavioral
intervention, n:
G1: 1
G2: 0
Son-Rise therapy, n:
G1: 1
G2: 0
Portage, n:
G1: 10
G2: 10
Special educational needs
setting, n (%):
G1: 30 (41)
G2: 24 (34)
Education setting with
specific provisions for
ASD, n (%):
G1: 8 (11)
G2: 10 (14)
Speech & language
therapy: Mean hrs ± SD:
G1: 9.5 ± 16.3 /case
G2: 9.8 ± 12.9 /case
N at enrollment:
G1: 77
G2: 75
N at follow-up:
G1: 74
G2: 72
Inclusion/ Exclusion
Criteria/ Population
SES:
Education (one parent with
qualifications after age 16
years), n (%):
G1: 65 (84)
G2: 47 (63)
Household income: NR
SES (dichotomized as at
least one parent in
professional or
administrative occupation
versus all others), n (%):
G1: 51 (66)
G2: 44 (59)
Diagnostic approach:
In Study
Diagnostic tool/method:
• Social and
communication domains
of the ADOS-G
• Two of three domains of
the ADI-R
Diagnostic category, n
(%):
Core autism: 152 (100)
Other characteristics: NR
C-12
Baseline
Measures Outcomes
G2: 24.4 ± 18.5
Parent-child
interaction: shared
attention time,
mean % ± SD:
G1: 65.3 ± 22.0
G2: 67.0 ± 21.9
ADI-R, mean
(range):
Reciprocal social
interaction:
G1: 17.9 (9–25)
G2: 18.2 (8–26)
Restricted,
repetitive, and
stereotyped
patterns:
G1: 5.2 (0–10)
G2: 5.6 (0–10)
Non-verbal
communication:
G1: 10.7 (3–14)
G2: 11.0 (3–14)
Verbal
communication:
G1 (n=22): 15.7 (9–
21)
G2 (n=25): 15.7
(10–23)
ADOS-G, mean
(range):
Module 1 (at most
single words) (G1:
n=60; G2: n=57)
Communication:
G1: 6.3 (4–8)
G2: 6.1 (4–8)
Reciprocal social
interaction:
G1: 10.9 (7–14)
G2: 10.8 (7–14)
Module 2 (phrase
speech) (G1: n=17;
G2: n=18)
Communication:
G1: 6.6 (5–9)
G2: 6.7 (5–9)
Reciprocal social
interaction:
G1: 9.1 (6–12)
Parent-child
interaction:
parental
synchrony,
mean % ± SD:
G1: 51.3 ± 19.6
G2: 32.6 ± 14.0
Change from
baseline, mean
% ± SD:
G1: 19.5 ± 21.3
G2: 1.4 ± 15.3
Parent-child
interaction: child
initiations, mean
% ± SD:
G1: 34.9 ± 19.7
G2: 26.0 ± 17.5
Change from
baseline, mean
% ± SD:
G1: 11.9 ± 25.6
G2: 1.6 ± 21.4
Parent-child
interaction:
shared attention
time, mean % ±
SD:
G1: 64.0 ± 25.7
G2: 55.6 ± 25.7
Change from
baseline, mean
% (SD):
G1: -1.4 ± 23.7
G2: -11.4 ± 28.4
Analysis adjusted
for center, age
group, sex, verbal
ability, nonverbal
ability,
socioeconomic
status, and
education
qualifications
were 2.28 (95%
CI 0.17 – 4.39) for
CSBS-DP social
composite scores;
Communication/
language:
ADOS-G