Therapies for Children With Autism Spectrum Disorders

Evidence Table: Therapies for Children with ASD (continued)
Study
Inclusion/ Exclusion
Description Intervention
Criteria/ Population
in procedures, and weekly Autistic disorder: 1 (12.5)
supervision and case PDD/autistic disorder: 1
consultation from director (12.5)
of home-based services G1b:
Developmental delay: 1
Measure of treatment (12.5)
fidelity reported: PDD: 6 (75)
No
Autistic disorder: 1 (12.5)
Luiselli et al.,
2000 (continued)
Author:
Moore et al.,
2000
Country:
US
Practice
setting:
Academic
Intervention
setting: School
Enrollment
period:
NR
Funding:
NR
Author industry
relationship
disclosures:
NR
Design:
RCT
Co-interventions held
stable during treatment:
NR
Concomitant therapies:
NR
N at enrollment:
G1a: 8
G1b: 8
N at follow-up:
G1a: 8
G1b: 8
Intervention:
Children taught 6 nouns
(3/day for two days) by
teacher or computer
instruction with follow-up
testing at 1 week postintervention
Assessment:
Learning , attention &
motivation measures
Groups:
G1: Teacher (Behavioral)
G2: Computer software
program (Educational)
Provider:
• Teacher
• Computer
Measure of treatment
fidelity reported:
No
Co-interventions held
stable during treatment:
NR
Concomitant therapies:
Other characteristics:
NR
Inclusion criteria:
• Children with autism
enrolled at one school
Exclusion criteria:
• See inclusion criteria
Age, range: 3-6 years
Mental age:
NR
Gender, n (%):
M: 12 (85.7)
F: 2 (14.3)
Race/ethnicity:
NR
SES:
Maternal education: NR
Household income: NR
Diagnostic approach:
NR
Diagnostic tool/method:
NR
Diagnostic category, n
(%):
Autism: 14 (100)
C-414
Baseline
Measures Outcomes
12.82 (P = 0.013)
G1b: 12.75 ±
11.31 (P = 0.015)
Social skills:
Social-Emotional,
mean change ±
SD:
G1a: 24.00 ±
21.98 (P = 0.018)
G1b: 17.25 ±
12.18 (P = 0.005)
Harms:
NR
Modifiers:
Duration of
treatment
predicted change
scores and was
significant for
communication (P
< 0.002),
cognition (P <
0.001) and socialemotional
(P <
0.001) domains.
NR Social skills:
Amount of time
spent paying
attention to
instruction, %:
G1: 62
G2: 97
F(1,13) = 13.28,
P < 0.01
Communication/
language:
Nouns recalled,
mean (%):
G1: 2.43 (41)
G2: 4.43 (74)
F(1,13) = 10.89,
P < 0.01
Educational/
cognitive/
academic
attainment:
Interest in
continuing
intervention at
end of session vs.
going to play, %:
G1: 0
G2: 56