Therapies for Children With Autism Spectrum Disorders

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1138. Gena A. The effects of prompting and social reinforcement on establishing social interactions with peers during the inclusion of four children with autism in preschool. International Journal of Psychology. 2006 Dec;41(6):541-554. X-3 1139. Gena A, Couloura S and Kymissis E. Modifying the Affective Behavior of Preschoolers with Autism Using In-Vivo or Video Modeling and Reinforcement Contingencies. Journal of Autism and Developmental Disorders. 2005 Oct;35(5):545- 556. X-3 1140. Gena A, Couloura S and Kymissis E. Modifying the affective behavior of preschoolers with autism using in-vivo or video modeling and reinforcement contingencies. J Autism Dev Disord. 2005 Oct;35(5):545-56. X-3 1141. Gena A, Krantz PJ, McClannahan LE, et al. Training and generalization of affective behavior displayed by youth with autism. J Appl Behav Anal. 1996 Fall;29(3):291-304. X-3, X-10 1142. Gencer O, Emiroglu FN, Miral S, et al. Comparison of long-term efficacy and safety of risperidone and haloperidol in children and adolescents with autistic disorder. An open label maintenance study. Eur Child Adolesc Psychiatry. 2008 Jun;17(4):217-25. X-1 1143. Genuis SJ. Is autism reversible? Acta Paediatr. 2009 Oct;98(10):1575-8. X-1, X-2, X-3, X-4 1144. Gerber S. A developmental perspective on language assessment and intervention for children on the autistic spectrum. Topics in Language Disorders. 2003 Apr-Jun;23(2):74- 94. X-3 1145. Gerdtz J. Evaluating behavioral treatment of disruptive classroom behaviors of an adolescent with autism. Research on Social Work Practice. 2000 Jan;10(1):98-110. X-1, X-3 1146. Gergely Gr. The obscure object of desire: “Nearly, but clearly not, like me’: Contingency preference in normal children versus children with autism. Bulletin of the Menninger Clinic. Special Issue: Cognitive and interactional foundations of attachment. 2001 Sum;65(3):411-426. X-4 1147. Gerig LH, Szanto J, Bichay T, et al. A translating-bed technique for total-body irradiation. Phys Med Biol. 1994 Jan;39(1):19-35. X-1, X-2, X-3, X-4, X-10 1148. Ghaziuddin M, Alessi N and Greden JF. Life events and depression in children with pervasive developmental disorders. J Autism Dev Disord. 1995 Oct;25(5):495-502. X-4, X-10 1149. Ghaziuddin M, Quinlan P and Ghaziuddin N. Catatonia in Autism: A Distinct Subtype? Journal of Intellectual Disability Research. 2005 Jan;49(1):102-105. X-2, X-3, X-4 1150. Ghaziuddin M, Tsai L and Ghaziuddin N. Clonidine for autism. Journal of Child and Adolescent Psychopharmacology. 1992 Win;2(4):239-240. X-3, X-10 1151. Ghaziuddin M, Tsai LY and Ghaziuddin N. Brief report: Haloperidol treatment of trichotillomania in a boy with autism and mental retardation. Journal of Autism and Developmental Disorders. 1991 Sep;21(3):365-371. X-3, X-10 D-80
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Comparative Effectiveness Review Nu
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This report is based on research co
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Acknowledgments We are indebted to
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Therapies for Children With Autism
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Dietary and Other Medical Intervent
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Figures Figure A. Analytic framewor
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Table A. Description of interventio
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Analytic Framework Figure A. Analyt
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Strength of evidence. The degree of
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epetitive behavior showed improveme
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subgroups of children, although the
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We encourage investigators to provi
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9. Remington B, Hastings RP, Kovsho
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46. Green J, Charman T, McConachie
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82. Reaven JA, Blakeley-Smith A, Ni
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120. Masi G, Cosenza A, Mucci M, et
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157. Evangeliou A, Vlachonikolis I,
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Introduction Need for Evidence for
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Interventions intended primarily to
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Table 1. Description of behavioral
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Serotonin reuptake inhibitors. Sero
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Table 3. Description of medical and
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Table 4. Description of allied heal
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Key Questions and Analytic Framewor
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Chapter 4 discusses the results in
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Methods This chapter documents proc
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• Did not present aggregated resu
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Additional behavioral interventions
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1. Did the study employ a group des
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Scoring: Studies minimally had to h
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These ratings of applicability do n
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Figure 2. Disposition of articles a
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• ABA-based approaches including
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education, children in the intensiv
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abilities. This finding is further
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Table 10. Outcomes of early intensi
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forecast behavior; perspective taki
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interaction with peers; outcome mea
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hyperactivity, inattention, challen
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Table 12. Outcomes of RCTs assessin
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Schedule for Affective Disorders an
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SCAS-P=Spence Child Anxiety Scale-P
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Summary of the literature. Jarusiew
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Table 14. Overview of educational s
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on the Ankara Developmental Screeni
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Checklist scores decreased by 8.4 f
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Table 15. Outcomes of studies asses
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evaluated the effects of risperidon
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that this somnolence improved over
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Table 17. Outcomes of RCTs of antip
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Serotonin Reuptake Inhibitors SRIs
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One prospective case series of esci
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Most participants were recruited fr
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Dietary and Other Medical Intervent
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Summary of the literature-other int
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withdrew after the first six weeks;
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therefore described separately belo
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addressed, 85 typically involves on
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In the second paper, 89 treatment s
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Table 25. Overview of CAM studies a
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Teacher and Parent Scales, behavior
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Because of the potentially increase
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Educational Interventions Child cha
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showed diminished response to escit
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oom as the other assessments, so it
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contrast group (n=18) on three meas
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and are based on consideration of f
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Few studies directly comparing the
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Strength of evidence. The strength
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While individual studies of CBT and
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Table 32. Summary of results of edu
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Table 33. Summary of results of med
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strength of this reviewed literatur
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Table 36. Intervention, strength of
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Table 37. Interventions/outcomes wi
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gains. 104 Other studies have seen
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percent of behavioral studies repor
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limited followup, lack of comparati
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individual intervention is warrante
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selecting participants for their st
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studies lacked an arm that consider
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23. Kanner L. Autistic Disturbances
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62. Dosman CF, Drmic IE, Brian JA,
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104. Ben-Itzchak E and Zachor DA. T
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142. Tyminski RF and Moore PJ. The
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177. Aman MG, McDougle CJ, Scahill
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214. Correia CT, Almeida JP, Santos
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252. Akhondzadeh S, Tajdar H, Moham
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290. Dawson G, Rogers S, Munson J,
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Acronyms/Abbreviations ABA Applied
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Appendix A. Exact Search Strings an
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Table A2. PsycINFO search strategie
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Therapies for Children with Autism
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Therapies for Children with ASD Sys
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Appendix C. Evidence Tables Tables
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Evidence Table. Therapies for child
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Country: US Practice setting: Clini
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Dunn-Geier et al., 2000 (continued)
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Evidence Table: Therapies for Child
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Appendix D. List of Excluded Studie
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31. Aarsland D, Cummings JL and Lar
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59. Ahearn WH, Clark KM, Gardenier
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89. Allison DB, Basile VC and MacDo
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118. Ando H, Yoshimura I and Wakaba
Page 617 and 618:
146. Atkinson RP, Jenson WR, Rovner
Page 619 and 620:
177. Bakare MO, Agomoh AO, Ebigbo P
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204. Baron-Cohen S, Scott FJ, Allis
Page 623 and 624:
233. Bebko JM, Perry A and Bryson S
Page 625 and 626:
262. Bergmann F, Stepp H, Metzger R
Page 627 and 628:
291. Birkan B, McClannahan LE and K
Page 629 and 630:
319. Boddy F, Rowan EN, Lett D, et
Page 631 and 632:
348. Bouma R and Schweitzer R. The
Page 633 and 634:
376. Broadstock M, Doughty C and Eg
Page 635 and 636: 404. Brudnak MA. Application of gen
Page 637 and 638: 432. Buitelaar JK. Why have drug tr
Page 639 and 640: 460. Butler DE, Nordin IC, L’Ital
Page 641 and 642: 489. Campbell M, Locascio JJ, Choro
Page 643 and 644: 517. Caronna EB, Augustyn M and Zuc
Page 645 and 646: 546. Case-Smith J and Miller H. Occ
Page 647 and 648: 574. Charlop MH, Burgio LD, Iwata B
Page 649 and 650: 602. Cheng CW, Cho SH, Taylor M, et
Page 651 and 652: 631. Cicero FR and Pfadt A. Investi
Page 653 and 654: 662. Collier D and Reid G. A compar
Page 655 and 656: 691. Coskun M, Karakoc S, Kircelli
Page 657 and 658: 718. Cullen LA, Barlow JH and Cushw
Page 659 and 660: 748. Davidovitch M, Holtzman G and
Page 661 and 662: 777. DeLeon IG, Fisher WW and Marhe
Page 663 and 664: 805. Devlin SD, Harber MM. Collabor
Page 665 and 666: 834. Doherty K, Fitzgerald M and Ma
Page 667 and 668: 863. Dudley LL, Johnson C and Barne
Page 669 and 670: 893. Dybvik AC. Autism and the Incl
Page 671 and 672: 924. Elder JH. In-home communicatio
Page 673 and 674: 953. Erickson CA, Posey DJ, Stigler
Page 675 and 676: 979. Faja S, Aylward E, Bernier R,
Page 677 and 678: 1008. Ferri R, Elia M, Agarwal N, e
Page 679 and 680: 1037. Fisher W, Kerbeshian J and Bu
Page 681 and 682: 1066. Fragala-Pinkham M, Haley SM a
Page 683 and 684: 1095. Furneaux B. Keeping the balan
Page 685: 1124. Garcaa-Villamisar D, Wehman P
Page 689 and 690: 1180. Goin-Kochel RP, Myers BJ and
Page 691 and 692: 1210. Gordon R, Handleman JS and Ha
Page 693 and 694: 1239. Grimaldi BL. The central role
Page 695 and 696: 1268. Guptill JT, Booker AB, Gibbs
Page 697 and 698: 1296. Hamdan-Allen G. Brief report:
Page 699 and 700: 1324. Hare DJ, Jones JPR and Paine
Page 701 and 702: 1356. Harrison S and Berry L. Valui
Page 703 and 704: 1386. Heilbrun AB, Jr., Blum N and
Page 705 and 706: 1414. Hetzroni OE and Shalem U. Fro
Page 707 and 708: 1443. Holburn CS. Counter the mistr
Page 709 and 710: 1473. Horner RH, Carr EG, Strain PS
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Page 717 and 718: 1591. Johnson CR, Butter EM, Handen
Page 719 and 720: 1619. Joyce PR. The medical model-w
Page 721 and 722: 1647. Karmali I, Greer RD, Nuzzolo-
Page 723 and 724: 1673. Kelly AB, Garnett MS, Attwood
Page 725 and 726: 1702. Kielinen M, Linna SL and Moil
Page 727 and 728: 1731. Klin A, Lin DJ, Gorrindo P, e
Page 729 and 730: 1761. Koegel RL and Frea WD. Treatm
Page 731 and 732: 1790. Kolmen BK, Feldman HM, Handen
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1874. Lattimore LP, Parsons MB and
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1903. Lee PC. Verification of a sim
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1932. Lerman DC, Vorndran C, Addiso
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1960. Licciardello CC, Harchik AE a
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1989. Liptak GS, Orlando M, Yinglin
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2015. Lorimer PA, Simpson RL, Myles
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2043. Luiselli JK, Kane A, Treml T,
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2071. MacFarlane JR and Kanaya T. W
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2099. Malone RP, Maislin G, Choudhu
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2127. Marin FZ. CAM versus nucleopl
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2157. Martineau J, Roux S, Adrien J
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2185. Matson JL and Lo Vullo SV. A
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2213. McCabe H. The Importance of P
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2240. McDougle CJ, Holmes JP, Carls
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2267. McHale SM, Olley JG, Marcus L
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2296. Merlo LJ, Lehmkuhl HD, Geffke
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2325. Minderaa RB, Anderson GM, Vol
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2354. Montgomery JM, Duncan CR and
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2385. Morrison RS, Sainato DM, Benc
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2413. Munesue T, Ono Y, Mutoh K, et
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2445. Napolitano DA, Tessing JL, Mc
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2474. Niederhofer H and Pittschiele
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2501. Nwora AJ and Gee BM. A case s
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2530. Olive ML, Lang RB and Davis T
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2559. Owens JA, Rosen CL and Mindel
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2589. Pansegrouw I and Alant E. Com
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2618. Paul C, Williams KE, Riegel K
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2646. Perry R, Nobler MS and Campbe
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2675. Piazza CC, Hagopian LP, Hughe
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2704. Poon L, Partika N and Bolman
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2734. Prizant BM. Speech-language p
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2764. Rapp JT, Vollmer TR, St. Pete
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2792. Reed P, Broomfield L, McHugh
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2819. Remington G, Sloman L, Konsta
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2849. Ringdahl JE, Kitsukawa K, And
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2877. Rogers SJ. Interventions that
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2908. Rossignol DA. Novel and emerg
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2939. Rutter M, Kreppner J, Croft C
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2967. Sandt D. Social Stories for S
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2994. Scanlon K. Art therapy with a
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3023. Schneider CK, Melmed RD, Bars
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3054. Schwartz IS, Sandall SR, Garf
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3085. Shafer MS, Egel AL and Neef N
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3115. Shipley-Benamou R, Lutzker JR
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3143. Siller M and Sigman M. The be
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3173. Smith C, Felce D, Jones E, et
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3202. Snyder A, Bossomaier T and Mi
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3230. Spero MH. The emancipation of
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3259. Stephens CE. Spontaneous imit
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3289. Strambi M, Longini M, Hayek J
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3318. Suzumura K. How an autistic b
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3346. Tager-Flusberg H and Calkins
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3376. Taylor I, O’Reilly M and La
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3407. Thunberg G, Ahlsen E and Sand
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3435. Trembath D, Balandin S, Toghe
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3464. Turner-Brown LM, Perry TD, Di
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3492. Van Der Putt R, Dineen C, Jan
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3522. Vitiello B. Recent NIMH clini
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3553. Walenski M, Mostofsky SH, Gid
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3581. Weber RC and Thorpe J. Teachi
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3610. Wheeler JJ, Baggett BA, Fox J
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3637. Williams B. Mental handicap n
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3669. Wimpory D, Chadwick P and Nas
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3698. Worth S and Reynolds S. The A
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3728. Young JM, Krantz PJ, McClanna
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3759. Zuddas A, Di Martino A, Mugli
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Appendix F. Approach to Categorizin
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APPENDIX G. Discussion of Recent Sy
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one a casein free regime. Diets wer
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outcome data as Type 6, defined as
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Yes—no disclosures to make G7 Bai
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Table G1. Characteristics of recent
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Random assignment Appropriate compa
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Study Group design Random assignmen
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APPENDIX I. Applicability Summary T
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Social skills (continued) Domain De
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