Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Author:
Inclusion criteria: Problem behavior: Problem
Sofronoff et al., Intervention:
NR
ECBI, number of behavior:
2004
Parent Management Exclusion criteria: problem behaviors, ECBI, number of
Country: Training (PMT), in the NR
mean ± SD: problem be-
Australia form of a 1-day workshop Age, years (range): G1: 17.44 ± 5.77 haviors, 3 months,
Practice or six weekly individual G1: 9.33 (6-12)
G2: 16.89 ± 5.84 mean ± SD:
setting:
sessions. Both groups Gender:
G3: 18.13 ± 5.19 G1: 12.50 ± 6.96
Academic followed a manual with six NR
ECBI, intensity of G2: 8.67 ± 4.93
Intervention components (1 hour Race/ethnicity:
problem behaviors, G3: 18.20 ± 6.21
setting:
each), including: psycho- NR
mean ± SD: G1/BL: P < 0.005
Clinic
education, comic strip SES:
G1: 149.72 ± 29.78 G2/BL: P <
Enrollment conversations (Gray, NR
G2: 140.44 ± 22.59 0.0001
period:
1994a), social stories Diagnostic approach: G3: 144.73 ± 26.39 G3/BL: P = NS
NR
(Gray, 1994b), manage- In Study
Social Skills: G1/G2: P = NS
Funding: ment of behavior prob- Diagnostic tool/method: Social skills G1/G3: P < 0.01
NR
lems, management of By pediatrician at clinic site questionnaire score, G2/G3: P <
Author industry rigid behaviors, routines, Diagnostic category, n mean ± SD: 0.0001
relationship and special interests, and (%):
G1: 23.66 ± 8.92 MANOVA: time
disclosures: anxiety management. Asperger: 51 (100) G2: 25.22 ± 10.01 (P < 0.0001),
NR
Groups:
Other characteristics: G3: 25.07 ± 6.64 treatment
Design: G1: workshop
NR
(P < 0.005), time
RCT
G2: individual
X treatment
Note:
G3: wait-list
(P < 0.001)
See related paper Provider:
ECBI, intensity of
with overlapping Clinical master’s or PhD
problem be-
participants, students completing an
haviors, 3 months,
Sofronoff et al., internship at the Behavior
mean ± SD:
2004 ({#1039}) Research and Therapy
G1: 129 ± 18.13
Center (University of
G2: 106.44 ±
Queensland)
22.99
Assessment:
G3: 144.40 ±
ECBI, Child’s Social Skills
31.85
questionnaire at baseline,
G1/BL: P <
4 weeks and 3 month
0.0001
follow-up
G2/BL: P <
Measure of treatment
0.0001
fidelity reported:
G3/BL: P = NS
No
G1/G2: P < 0.01
Co-interventions held
G1/G3: P = NS
stable during treatment:
G2/G3: P <
NR
0.0001
Concomitant therapies:
MANOVA: time
NR
(P < 0.0001),
N at enrollment:
treatment (P <
G1: 18
0.01), time X
G2: 18
treatment (P <
G3: 15
N at follow-up:
G1: 18
G2: 18
G3: 15
0.001)
Sofronoff et al.,
Social Skills:
2004 (continued)
Social skills
questionnaire
score, 3 months,
mean ± SD:
G1: 31 ± 9.01
C-341