Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Inclusion/ Exclusion Baseline
Description Intervention
Criteria/ Population Measures Outcomes
G2: 2
G1: 5.65 ± 1.72
Extended:
G2: 5.54 ± 1.53
G1: 1
Harms:
G2: 0
NR
Both Parents:
Modifiers:
G1: 15
G2: 20
Relationship of primary
participating parent to
child, n:
Mother:
G1: 29
G2: 25
Father:
G1: 0
G2: 4
NR
Whitingham et al.,
Grandmother:
2009
G1: 0
Whitingham et al.,
2009† (continued)
G2: 1
Author:
Intervention:
Inclusion criteria: Social skills: Social skills:
Wood et al., 2009 Immediate treatment or 3- • Met research criteria for SRS total score, SRS total score,
Country: month wait list
ASD
mean ± SD (range): mean ± SD
US
Therapists worked with • Had at least one anxiety G1: 113 ± 18.27
Practice families for 16 weekly disorder
(87-145)
setting:
sessions, each lasting 90 • Psychiatric medication, if G2: 116 ± 30.19
Academic min (about 30 min with used, was at a stable (61-151)
Intervention the child and 60 min with dose prior to intake and SRS T-score ≥ 70,
setting:
the parents/family), throughout the trial n:
School, home implementing a version of Exclusion criteria: G1: 9/9
Enrollment the Building Confidence • IQ less than 70 G2: 9/10
period:
CBT program
• Concurrent
March 2006 to Assessments:
psychotherapy
August 2007 Posttreatment assess- Age, years ± SD (range):
Funding: ments were completed on 9.37 ± 1.42 (7-11)
Cure Autism Now the final day of treatment Mental age:
Foundation, NIH or within 1 week of NR
Author industry termination; post-waitlist Gender, n (%):
relationship assessments were Male: 16 (84)
disclosures: conducted 3 months after Female: 3 (16)
NR
the baseline assessment Race/ethnicity, n (%):
Design: but before initializing CBT Caucasian: 10 (53)
RCT
Groups:
Asian: 4 (21)
Note:
G1: immediate treatment Native American/
Methodology data G2: 3-month waitlist caucasian: 2 (11)
extracted from Provider:
Latino/Asian: 1 (5)
Wood et al. 2009 Four doctoral students in African American/
({#3618}), where clinical or educational caucasian: 1 (5)
more detailed psychology, and one SES:
information can be postdoctoral fellow in Maternal education: NR
found
psychology; therapists Primary parent, college
received training and degree, n (%): 15 (79)
weekly supervision Household income: NR
Measure of treatment Diagnostic approach:
fidelity reported: In Study and Referral
Yes
Diagnostic tool/method:
Co-interventions held ADI-R; ADOS – Module 3;
(range):
G1: 89 ± 26.39
(53-140)
G2: 110.30 ±
29.22 (53-146)
G1/G2: P < 0.05
SRS T-score ≥
70, immediate
post-treatment, n:
G1: 7/9
G2: 9/10
SRS T-score ≥
70, 3 months
post-treatment,
LOCF, n:
G1: 4/9
G2: NA
SRS social
motivation score,
mean:
G1: NR
G2: NR
G1/G2: P < 0.05
(favoring G1)
SRS social
awareness score,
mean:
G1: NR
G2: NR
G1/G2: P < 0.05
(favoring G1)
SRS social
cognition score,
mean:
C-106