Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Inclusion/ Exclusion
Description Intervention
Criteria/ Population
intervention
Diagnostic approach:
In Study & Referral
Golan et al.
2010 (continued)
Assessments:
ADI-R, Children’s Autism
Spectrum Test (CAST),
British Picture Vocabulary
Scale (BPVS), emotional
vocabulary, situationfacial
expression
matching (SEM) task
Emotion recognition tasks
were conducted on
computer using
PowerPoint beginning
with Level 1 with 16
questions at each level
Groups:
G1: ASD children given
Transporters DVD
intervention, at least 3
episodes per day for 4
weeks
G2: ASD children with no
intervention (standard
school curriculum)
G3: typically developing
controls with no
intervention
Provider:
Parental supervision
during DVD viewing
session
Treatment manual
followed: NR
Defined protocol
followed: yes
Measure of treatment
fidelity reported: yes
Co-interventions held
stable during treatment:
NR
Concomitant therapies,
n (%):
NR
N at enrollment:
G1: 20
G2: 19
G3: 18
N at follow-up:
Diagnostic tool/method:
In-Study: ADI-R & CAST
for G1; CAST for G2;
CAST for G3
Referral: G1 & G2
diagnosed in specialist
centers using American
Psychiatric Association
established criteria
Diagnostic category, n
(%):
Autism:
G1: 20 (51)
G2: 19 (49)
G3: 0
Other characteristics:
Days between
assessments, mean ± SD
(range)
G1: 28.8 ± 3.3 (24–38)
G2: 28.2 ± 3.8 (22–37)
G3: 27.8 ± 1.4 (25–31)
C-10
Baseline
Measures Outcomes
SEM-Level 2: Group x time: P <
(max = 16)
G1: 9.80 ± 2.91
0.001
G2: 9.33 ± 2.91 SEM-Level 3:
G3: 12.72 ± 2.30 (max = 16)
G1: 13.30 ± 2.27
SEM-Level 3: G2: 9.61 ± 2.83
(max = 16) G3: 12.89 ± 1.78
G1: 9.85 ± 2.43 Group: P < 0.001
G2: 9.67 ± 2.77 Time: P < 0.001
G3: 13.00 ± 2.28 Group x time: P <
0.001
G1 improved
significantly from
Time 1 to Time 2
on all four tasks
(P < 0.001)
Harms:
NR
Modifiers:
Positive
correlation
between verbal
ability and
improvement on
the Level 2 SEM
in G1 (r = 0.58, P
< 0.01); positive
correlation
between verbal
ability and
improvement on
the Emotional
Vocabulary task in
G3 (r = 0.57, P <
0.02).
No other
significant
correlations
between age,
verbal ability, time
between two
assessment
meetings and
improvement
scores for each
task.