Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Author:
Intervention:
Inclusion criteria: Communication/ Communication/
Solomon et al., • Social adjustment • Ages 8-12 years language: language:
2004
Country:
enhancement
curriculum targeting
• Prior diagnosis of High
Functioning Autism
DANVA score, DANVA score,
mean ± SD (range): mean ± SD
US
social skills in a group (HFA), Asperger Adult faces: (range):
Practice
setting with
Syndrome (AS) or G1a: 12.2 ± 1.1 (11- Adult faces:
setting:
standardized agenda Pervasive Develop- 14)
G1a: 13.4 ± 1.1
Academic,
including welcome mental Disorder NOS G1b: 10.5 ± 1.3 (9- (12-15)
medical center song, review of
(PDDNOS) confirmed by 12)
G1b: 12.8 ± 2.9
Intervention previous lessons, ADOS-G and ADI-R and G2a: 11.8 ± 2.2 (10- (9-15)
setting:
conversational and DSM-IV criteria for HFA, 15)
G2a: 11.2 ± 1.3
Clinic
motor activity skills PDDNOS or AS based G2b: 12.4 ± 1.3 (11- (10-13)
Enrollment interventions
on clinical interview 14)
G2b: 11.8 ± 2.4
period:
• Curriculum focused on • Full Scale IQ score from Child faces: (10-15)
NR
teaching skills in within past 2 years ≥75 G1a: 11.6 ± 1.5 (10- G1/BL: P < 0.05
Funding:
emotion/facial
as measured by WISC- 14)
G1/G2: P < 0.05
UC Davis MIND expression recognition III or WASI
G1b: 12.0 ± 2.4 (10- Ga/Gb: P = NS
Institute, UC Davis in self and others, • Demonstrated ability to 15)
Child faces:
Health System, theory of mind,
pass Smarties false G2a: 13.0 ± 1.2 (12- G1a: 13.2 ± 1.8
UC Davis
executive functions belief task
15)
(11-16)
Author industry with emphasis on Exclusion criteria: G2b: 12.8 ± 0.9 (12- G1b: 12.0 ± 1.8
relationship problem solving, and • Serious conduct 14)
(10-14)
disclosures: conversational skills problems
Total faces: G2a: 12.8 ± 1.5
NR
• Parent training Age, months (range): G1a: 23.8 ± 1.3 (23- (11-15)
Design:
component with focus G1a: 103 (93-117) 26)
G2b: 11.8 ± 2.1
RCT, age and IQ on enhancing parental G1b: 130 (111-146) G1b: 22.5 ± 2.9 (19- (9-14)
matched interven- understanding of G2a: 100 (88-117) 26)
G1/BL: P < 0.05
tion and waiting child’s social problems G2b: 122 (108-140) G2a: 24.8 ± 3.1 (22- G1/G2: P < 0.05
list control • Weekly problem Mental age:
30)
Ga/Gb: P = 0.05
behavior logs VIQ, mean (range): G2b: 25.2 ± 2.2 (23- Total faces:
completed by parents G1a: 126 (117-136) 28)
G1a: 26.6 ± 1.5
to facilitate child social G1b: 86 (75-94)
Theory of Mind (25-29)
behavior management G2a: 121 (92-142) score, mean ± SD G1b: 24.8 ± 3.4
Assessments:
G2b: 82 (59-91)
(range):
(20-28)
DANVA, Theory of Mind, PIQ, mean (range): Strange stories: G2a: 24.0 ± 2.3
Faux Pas Stories, Test of G1a: 103 (89-112) G1a: 10 ± 1 (9-11) (22-28)
Problem Solving, G1b: 88 (63-115) G1b: 6.5 ± 1.7 (7- G2b: 23.6 ± 3.3
conducted in clinic by G2a: 114 (85-136) 11)
(19-27)
examiner; Children’s G2b: 108 (90-122) G2a: 9.2 ± 1.6 (4-8) Theory of Mind
Depression Inventory, FSIQ, mean (range): G2b: 7.4 ± 1.3 (6-9) score, mean ± SD
Beck Depression G1a: 115 (99-124) Faux pas:
(range):
Inventory competed by G1b: 86 (75-100) G1a: 2.6 ± 2.1 (0-5) Strange stories:
child with mother present G2a: 119 (88-143) G1b: 0.75 ± 0.5 G1a: 10.4 ± 0.9
in clinic; parent-completed G2b: 95 (83-104) (1-4)
(9-11)
weekly social behavior Gender, n (%):
G2a: 2.8 ± 1.3 (0-1) G1b: 7.3 ± 0.5 (7problem
logs
Male: 18 (100)
G2b: 1.2 ± 0.5 (1-2) 11)
Duration:
Female: 0 (0)
G2a: 9.4 ± 1.8 (7-
20 weeks
Race/ethnicity:
8)
Frequency: weekly, 1.5 NR
G2b: 7.5 ± 1.3 (6hours/week
SES:
9)
Maternal education: NR
G1-2/BL: P = NS
Household income: NR
G1/G2: P = NS
Solomon et al., Provider:
Diagnostic approach: TOPS elementary- Faux pas:
2004 (continued) Social skills group leaders In study
revised, percentile G1a: 5.4 ± 0.9 (4consisting
of psycholo-
rank score, mean ± 6)
gists, a psychiatrist, a Diagnostic tool/method: SD (range): G1b: 3.0 ± 2.2 (1speech
and language ADOS-G and ADI-R and G1a: 32.2 ± 13.9 6)
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