Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Inclusion/ Exclusion
Description Intervention
Criteria/ Population
G1: intensive behavioral/
oral therapy
Tracheostomy: 0
Cleft palate: 0
Laud et al.,
2009
(continued)
Author:
Marcus et al.,
Provider:
• Main care providers:
behavioral therapist,
occupational and/or
speech pathologist
• Others: gastroenterologist,
pediatrician,
nurse practitioner, and
nutritionist
• Social worker for care
providers of children
Measure of treatment
fidelity reported:
No
Measure of inter-rater
reliability reported:
Yes
Co-interventions held
stable during treatment:
NR
Concomitant therapies:
NR
N at enrollment:
G1: 46
N at follow-up:
G1: 29
Intervention:
Aripiprazole, 2 mg/day for
Prematurity, n (%):
< 32 weeks: 6 (13)
32-38 weeks: 9 (19.6)
Inclusion criteria:
• Autistic disorder
C-67
Baseline
Measures Outcomes
Texture of foods
follow-up survey,
years from
baseline, n (%):
Higher:
1-3: 4/14 (28.6)
3+: 9/15 (60)
Same:
1-3: 7/14 (50)
3+: 4/15 (26.7)
Lower:
1-3: 1/14 (7.1)
3+: 1/15 (6.7)
Protocol usage,
follow-up survey,
years from
baseline, n (%):
Using:
1-3: 7/14 (50.0)
3+: 5/15 (33.3)
Using modified
version:
1-3: 3/14 (21.4)
3+: 3/15 (20)
Not using:
1-3: 4/14 (28.6)
3+: 6/15 (40)
Caregiver
Assessment:
CEBI total eating
problems score,
mean:
G1: 99.62
G1/BL: P < 0.004
Caregiver satisfaction
score,
mean:
G1: 4.48
Program recommendation,followup
survey, years,
n (%):
Yes:
1-3: 12/14 (85.7)
3+: 15/15 (100)
Depends:
1-3: 2/14 (14.3)
3+: 0/15
No:
1-3: 0/14
3+: 0/15
Harms:
NR
Modifiers:
NR
Overall ratings: Overall ratings:
CGI-S score, LOCF, CGI-S, week 8,