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Therapies for Children With Autism Spectrum Disorders

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Table 12. Outcomes of RCTs assessing play-/interaction-based interventions<br />

Author, year, country Age, mean ± SD (range)<br />

Key outcomes<br />

Groups, N enrollment/ N final<br />

Study quality<br />

IQ, mean ± SD<br />

Parent-focused interventions<br />

Solomon et al. 161 2008, US G1: 8.2 yrs ± 1.7<br />

• Challenging behaviors decreased in both<br />

G2: 8.1 yrs ± 2.2<br />

groups.<br />

G1: Parent training focused on<br />

• Scores declined on BASC Hyperactivity Scale<br />

behavior management and NR<br />

<strong>for</strong> G1 but not G2.<br />

requesting (PCIT), 10/10<br />

G2: Wait list, 9/9<br />

• Score on BASC Adaptability Scale increased<br />

significantly <strong>for</strong> G1.<br />

Quality: Fair<br />

• Parents of G1 children reported significantly<br />

less atypicality on the BASC scale.<br />

Kasari et al. 155,156 2006, US G1: 43.2 ± 7.05<br />

• <strong>Children</strong> in the intervention groups showed<br />

G2: 42.67 ± 6.93<br />

greater growth in expressive language,<br />

G1: Joint attention intervention, G3: 41.94 ± 4.93<br />

initiation of joint attention, and duration of<br />

20/20<br />

child-initiated joint attention than did control<br />

G2: Symbolic play intervention, NR<br />

group children (p=

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