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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD<br />

Study<br />

Inclusion/Exclusion<br />

Description Intervention<br />

Criteria/Population<br />

Author:<br />

Intervention:<br />

Inclusion criteria:<br />

Tyminski et al., Group psychotherapy, <strong>for</strong> • Diagnosis of DSM-IV<br />

2008<br />

an average 14 months <strong>for</strong> criteria <strong>for</strong> PDD<br />

Country: 2 groups of 6 and 3 • Capacity <strong>for</strong> verbal<br />

US<br />

Practice<br />

setting:<br />

Community<br />

Intervention<br />

setting:<br />

School and home<br />

Enrollment<br />

period:<br />

NR<br />

Funding:<br />

NR<br />

Author industry<br />

relationship<br />

disclosures:<br />

NR<br />

Design:<br />

Prospective case<br />

series<br />

groups of 5<br />

communication<br />

Assessment:<br />

• No history of verbal<br />

Social skills at home aggression towards<br />

assessed by VABS and at peers<br />

school by the Social Skills Exclusion criteria:<br />

Checklist; baseline social • See inclusion criteria<br />

development by teachers Age, years (range):<br />

Follow-up assessment of G1: 9.2 (5-16)<br />

all study measures at 4 Mental age:<br />

months to 3 years after NR<br />

start of study therapy Gender, n (%):<br />

Groups:<br />

Male: 33 (85)<br />

G1: group psychotherapy Female: 6 (15)<br />

Provider:<br />

Race/ethnicity, n (%):<br />

Therapists<br />

White: 12 (31)<br />

Measure of treatment Asian: 12 (31)<br />

fidelity reported: Hispanic: 9 (23)<br />

No<br />

African American: 2 (5)<br />

Co-interventions held Multiracial: 4 (10)<br />

stable during treatment: SES:<br />

NR<br />

Maternal education: NR<br />

Concomitant therapies: Household income: NR<br />

NR<br />

Diagnostic approach:<br />

N at enrollment: In Study<br />

G1: 39 (100)<br />

Diagnostic tool/method:<br />

N at follow-up:<br />

DSM-IV<br />

G1: 27 (69)<br />

Diagnostic category, n<br />

(%):<br />

<strong>Autism</strong>: 15 (38)<br />

PDD-NOS: 21 (54)<br />

Aspergers: 3 (8)<br />

Other characteristics:<br />

Theory of Mind: NR<br />

C-177<br />

Baseline<br />

Measures Outcomes<br />

Social skills: Social skills:<br />

VABS socialization, VABS<br />

developmental age, socialization,<br />

months ± SD developmental<br />

(range):<br />

age, months ± SD<br />

G1: 33 ± 15.3 (range):<br />

(13-86)<br />

G1: 46 ± 18.2<br />

Correlation between (17-90)<br />

VABS and baseline G1/BL: P < 0.001<br />

measures: Correlation<br />

Age at intake: 0.38 between follow-up<br />

(P < 0.05)<br />

VABS and other<br />

Theory of Mind: 0.35 measures:<br />

(P < 0.05)<br />

Theory of Mind:<br />

Social Skills 0.49 (P < 0.01)<br />

Checklist score, Baseline VABS:<br />

mean ± SD (range): 0.74 (P < 0.0001)<br />

G1: 2.5 ± 0.8 Duration of<br />

(1.4-4.7)<br />

therapy: -0.44<br />

Correlation between (P < 0.01)<br />

SSC score and Social Skills<br />

baseline measures: Checklist score,<br />

Age: 0.29 (P < 0.10) mean ± SD<br />

(range):<br />

G1: 2.9 ± 0.7<br />

(1.2-4.0)<br />

G1/BL: P < 0.01<br />

Correlation<br />

between follow-up<br />

SSC score and<br />

other measures:<br />

Baseline SSC:<br />

0.54 (P < 0.001)<br />

Correlation<br />

between change<br />

in SSC score and<br />

other measures:<br />

Age at intake:<br />

-0.32 (P < 0.10)<br />

Harms:<br />

NR<br />

Modifiers:<br />

Age at intake,<br />

theory of mind,<br />

and duration of<br />

therapy

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