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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD<br />

Study<br />

Inclusion/Exclusion Baseline<br />

Description Intervention<br />

Criteria/Population Measures Outcomes<br />

Author:<br />

Intervention:<br />

Inclusion criteria: Overall ratings: Overall ratings:<br />

Stahmer & <strong>Children</strong>’s Toddler School • participated in CTS VABS, n, mean age VABS, n, mean<br />

Ingersoll, (CTS),<br />

program <strong>for</strong> a minimum equivalent: age equivalent:<br />

2009<br />

• inclusive classroom of 6 months<br />

G1: 16, 14 G1: 16, 21<br />

serving 8 children with • received from a clinician<br />

Country:<br />

ASD and 8 typically not associated with the GARS, n, mean ± GARS, n, mean ±<br />

US<br />

developing children (4 project an independent SD:<br />

SD:<br />

in the morning, 4 in the diagnosis of ASD G1: 19, 87.2 ± 11.2 G1: 19, 76.5 ±<br />

Practice<br />

afternoon), inclusion • minimum nonverbal<br />

23.0<br />

setting: Academic sessions 3 hours a day, mental age of 12 mo. (on Social skills: P < 0.05<br />

5 days a week,<br />

BSID-II)<br />

VABS Socialization,<br />

Intervention • special skills training: 30 • less than 2 years 6 mo. n, mean ± SD: Social skills:<br />

setting:<br />

min/4 days a week of of age<br />

G1: 16, 70.4 ± 8.9 VABS<br />

Classroom one-to-one teaching<br />

Socialization, n,<br />

Enrollment<br />

period:<br />

NR<br />

• arranged like typical<br />

toddler classroom (i.e.<br />

toys <strong>for</strong> appropriate<br />

levels of paly)<br />

Exclusion criteria:<br />

See above<br />

Age, mean/months<br />

VABS socialization mean ± SD:<br />

range of functioning, G1: 16, 75.0 ±<br />

n (%):<br />

10.9<br />

Typical range 1 (6) P < 0.05<br />

• Family participation<br />

Funding:<br />

component: weekly 2<br />

<strong>Children</strong>’s Hospital hour home visit, home<br />

Research grant teacher and<br />

NIH<br />

psychologist<br />

Cali<strong>for</strong>nia Early accompany family<br />

Start<br />

through transition<br />

Author industry<br />

(range):<br />

27.6 (22-31)<br />

Reported functional<br />

social interaction<br />

Mental age, BSID-II mean skills, n (%):<br />

± SD:<br />

Avoidant: 8 (40)<br />

G1: 67.2 ± 14.7<br />

Facilitated: 8 (40)<br />

(n=19)<br />

Parallel play: 4 (20)<br />

Responsive to<br />

VABS<br />

socialization<br />

range of<br />

functioning, n (%):<br />

Typical range: 5<br />

(31)<br />

relationship<br />

disclosures:<br />

NR<br />

Design:<br />

Case series,<br />

prospective<br />

Assessments:<br />

Gender: n (%):<br />

Administered at entry and M, 16 (80%)<br />

approx. 1 week be<strong>for</strong>e F, 4 (20%)<br />

child completed<br />

treatment: BSID-II (by Race/ethnicity, n (%):<br />

program psychologist), White: 12(60)<br />

VABS (by program Asian: 2 (10)<br />

director to parent), GARS Hispanic: 4(20)<br />

(parent questionnaire), Filipino: 2(10)<br />

and checklist of functional<br />

skills developed by SES:<br />

authors (by program Maternal education: NR<br />

psychologist).<br />

Mean age at exit: 35 mo. Household income: NR<br />

peers: 0 (0) Reported<br />

Reciprocal play: 0 functional social<br />

(0)<br />

interaction skills, n<br />

(%):<br />

Communication/ Avoidant: 0 (0)<br />

language: Facilitated: 3 (15)<br />

VABS<br />

Parallel play: 5<br />

Communication, n, (25)<br />

mean ± SD: Responsive to<br />

G1: 16, 71.1 ± 13.9 peers: 5 (25)<br />

Reciprocal play: 7<br />

VABS<br />

(35)<br />

communication P < 0.01<br />

range of functioning,<br />

n (%):<br />

Communication/<br />

Groups:<br />

G1: <strong>Children</strong>’s Toddler<br />

School (CTS)<br />

Four Factor Index of Social Severely delayed language:<br />

Status, n (%):<br />

range: 1 (6) VABS<br />

Major business/<br />

Mildly delayed Communication,<br />

professional: 5( 25) range: 7 (44) n, mean ± SD:<br />

Med. business/minor Borderline range: 7 G1: 16, 79.3 ±<br />

professional: 10(50) (44)<br />

17.1<br />

Skilled workers: 2(10) Average range: 1 (6) P < 0.01<br />

Semiskilled workers: 3(15)<br />

44% of children<br />

Unskilled laborers: 0(0)<br />

showed increases<br />

Provider:<br />

• Special and early<br />

education classroom<br />

teachers, at least<br />

bachelor’s degree<br />

• Speech<br />

therapist/occupational<br />

therapist<br />

Diagnostic approach:<br />

Referral<br />

Diagnostic tool/method:<br />

DSM-IV<br />

C-346<br />

Reported functional<br />

communication<br />

skills, %:<br />

No functional<br />

communication<br />

system: 50<br />

VABS<br />

communication<br />

range of<br />

functioning, n (%):

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