Therapies for Children With Autism Spectrum Disorders

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2632. Penrod B, Wallace MD and Dyer EJ. Assessing potency of high- and low-preference reinforcers with respect to response rate and response patterns. J Appl Behav Anal. 2008 Summer;41(2):177-88. X-3 2633. Pepperberg IM and Sherman D. Proposed use of two-part interactive modeling as a means to increase functional skills in children with a variety of disabilities. Teach Learn Med. 2000 Fall;12(4):213-20. X-3 2634. Perel I. Deinstitutionalization at a large facility: a focus on treatment. Res Dev Disabil. 1992;13(1):81-6. X-2, X-3, X-4, X-10 2635. Perez-Gonzalez LA and Williams G. Multicomponent procedure to teach conditional discriminations to children with autism. Am J Ment Retard. 2002 Jul;107(4):293-301. X- 3 2636. Perez-Soler R, Yang LY, Drewinko B, et al. Increased cytotoxicity and reversal of resistance to cis-diamminedichloro-platinum(II) with entrapment of cis-Bisneodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in multilamellar lipid vesicles. Cancer Res. 1988 Aug 15;48(16):4509-12. X-1, X-3, X-4, X-10 2637. Perquin M, Michel GH, de Beaufort C, et al. Changes in diabetes prevalence and treatment in the last ten years in Luxembourg. A lesson from the United Kingdom prospective diabetes study? Diabetes Metab. 2005 Nov;31(5):499-502. X-1, X-4 2638. Perriol MP, Dujardin K, Derambure P, et al. Disturbance of sensory filtering in dementia with Lewy bodies: comparison with Parkinson’s disease dementia and Alzheimer’s disease. J Neurol Neurosurg Psychiatry. 2005 Jan;76(1):106-8. X-1, X-3, X-4 2639. Perry A, Bryson S and Bebko J. Brief report: Degree of facilitator influence in facilitated communication as a function of facilitator characteristics, attitudes, and beliefs. J Autism Dev Disord. 1998 Feb;28(1):87-90. X-10 2640. Perry A and Factor DC. Psychometric validity and clinical usefulness of the Vineland Adaptive Behavior Scales and the AAMD Adaptive Behavior Scale for an autistic sample. J Autism Dev Disord. 1989 Mar;19(1):41-55. X-4, X-10 2641. Perry A, Flanagan HE, Dunn Geier J, et al. Brief report: the Vineland Adaptive Behavior Scales in young children with autism spectrum disorders at different cognitive levels. J Autism Dev Disord. 2009 Jul;39(7):1066-78. X-4 2642. Perry DW, Marston GM, Hinder SA, et al. The phenomenology of depressive illness in people with a learning disability and autism. Autism. 2001 Sep;5(3):265-75. X-1, X-2, X- 3, X-4 2643. Perry R, Campbell M, Adams P, et al. Long-term efficacy of haloperidol in autistic children: continuous versus discontinuous drug administration. J Am Acad Child Adolesc Psychiatry. 1989 Jan;28(1):87-92. X-10 2644. Perry R, Campbell M, Green WH, et al. Neuroleptic-related dyskinesias in autistic children: a prospective study. Psychopharmacol Bull. 1985;21(1):140-3. X-10 2645. Perry R, Cohen I and DeCarlo R. Case study: Deterioration, autism, and recovery in two siblings. Journal of the American Academy of Child & Adolescent Psychiatry. 1995 Feb;34(2):232-237. X-3, X-10 D-184
2646. Perry R, Nobler MS and Campbell M. Tourette-like symptoms associated with neuroleptic therapy in an autistic child. Journal of the American Academy of Child & Adolescent Psychiatry. 1989 Jan;28(1):93-96. X-3, X-10 2647. Perry R, Pataki C, Munoz-Silva DM, et al. Risperidone in children and adolescents with pervasive developmental disorder: pilot trial and follow-up. J Child Adolesc Psychopharmacol. 1997;7(3):167-79. X-10 2648. Perry W, Minassian A, Lopez B, et al. Sensorimotor gating deficits in adults with autism. Biol Psychiatry. 2007 Feb 15;61(4):482-6. X-1, X-4 2649. Persson B. Brief report: A longitudinal study of quality of life and independence among adult men with autism. J Autism Dev Disord. 2000 Feb;30(1):61-6. X-1, X-3, X-4 2650. Persson B, Nordstrom B, Petersson K, et al. Screening for infants with developmental deficits and/or autism: a Swedish pilot study. J Pediatr Nurs. 2006 Aug;21(4):313-24. X- 4 2651. Peterson CC. Theory-of-mind development in oral deaf children with cochlear implants or conventional hearing aids. J Child Psychol Psychiatry. 2004 Sep;45(6):1096-106. X-4 2652. Peterson CC. Mind and body: concepts of human cognition, physiology and false belief in children with autism or typical development. J Autism Dev Disord. 2005 Aug;35(4):487- 97. X-4 2653. Peterson CC, Garnett M, Kelly A, et al. Everyday social and conversation applications of theory-of-mind understanding by children with autism-spectrum disorders or typical development. Eur Child Adolesc Psychiatry. 2009 Feb;18(2):105-15. X-4 2654. Peterson CC and Siegal M. Deafness, conversation and theory of mind. J Child Psychol Psychiatry. 1995 Mar;36(3):459-74. X-1, X-3, X-4, X-10 2655. Peterson CC and Siegal M. Domain specificity and everyday biological, physical, and psychological thinking in normal, autistic, and deaf children. New Dir Child Dev. 1997 Spring(75):55-70. X-10 2656. Peterson CC and Slaughter V. Theory of Mind (ToM) in Children with Autism or Typical Development: Links between Eye-Reading and False Belief Understanding. Research in Autism Spectrum Disorders. 2009 Apr-Jun;3(2):462-473. X-4 2657. Peterson CC, Slaughter VP and Paynter J. Social maturity and theory of mind in typically developing children and those on the autism spectrum. J Child Psychol Psychiatry. 2007 Dec;48(12):1243-50. X-4 2658. Peterson L, McLaughlin TF, Weber KP, et al. The effects of model, lead, and test technique with visual prompts paired with a fading procedure to teach “where” to a 13year-old echolalic boy with autism. Journal of Developmental and Physical Disabilities. 2008 Feb;20(1):31-39. X-1, X-3 2659. Peterson SMP, Caniglia C and Royster AJ. Application of choice-making intervention for a student with multiply maintained problem behavior. Focus on Autism and Other Developmental Disabilities. 2001 Win;16(4):240-246. X-3 D-185
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Comparative Effectiveness Review Nu
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This report is based on research co
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Acknowledgments We are indebted to
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Therapies for Children With Autism
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Dietary and Other Medical Intervent
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Figures Figure A. Analytic framewor
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Table A. Description of interventio
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Analytic Framework Figure A. Analyt
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Strength of evidence. The degree of
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epetitive behavior showed improveme
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subgroups of children, although the
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We encourage investigators to provi
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9. Remington B, Hastings RP, Kovsho
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46. Green J, Charman T, McConachie
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82. Reaven JA, Blakeley-Smith A, Ni
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120. Masi G, Cosenza A, Mucci M, et
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157. Evangeliou A, Vlachonikolis I,
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Introduction Need for Evidence for
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Interventions intended primarily to
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Table 1. Description of behavioral
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Serotonin reuptake inhibitors. Sero
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Table 3. Description of medical and
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Table 4. Description of allied heal
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Key Questions and Analytic Framewor
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Chapter 4 discusses the results in
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Methods This chapter documents proc
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• Did not present aggregated resu
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Additional behavioral interventions
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1. Did the study employ a group des
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Scoring: Studies minimally had to h
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These ratings of applicability do n
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Figure 2. Disposition of articles a
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• ABA-based approaches including
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education, children in the intensiv
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abilities. This finding is further
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Table 10. Outcomes of early intensi
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forecast behavior; perspective taki
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interaction with peers; outcome mea
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hyperactivity, inattention, challen
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Table 12. Outcomes of RCTs assessin
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Schedule for Affective Disorders an
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SCAS-P=Spence Child Anxiety Scale-P
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Summary of the literature. Jarusiew
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Table 14. Overview of educational s
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on the Ankara Developmental Screeni
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Checklist scores decreased by 8.4 f
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Table 15. Outcomes of studies asses
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evaluated the effects of risperidon
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that this somnolence improved over
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Table 17. Outcomes of RCTs of antip
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Serotonin Reuptake Inhibitors SRIs
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One prospective case series of esci
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Most participants were recruited fr
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Dietary and Other Medical Intervent
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Summary of the literature-other int
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withdrew after the first six weeks;
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therefore described separately belo
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addressed, 85 typically involves on
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In the second paper, 89 treatment s
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Table 25. Overview of CAM studies a
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Teacher and Parent Scales, behavior
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Because of the potentially increase
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Educational Interventions Child cha
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showed diminished response to escit
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oom as the other assessments, so it
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contrast group (n=18) on three meas
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and are based on consideration of f
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Few studies directly comparing the
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Strength of evidence. The strength
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While individual studies of CBT and
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Table 32. Summary of results of edu
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Table 33. Summary of results of med
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strength of this reviewed literatur
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Table 36. Intervention, strength of
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Table 37. Interventions/outcomes wi
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gains. 104 Other studies have seen
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percent of behavioral studies repor
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limited followup, lack of comparati
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individual intervention is warrante
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selecting participants for their st
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studies lacked an arm that consider
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23. Kanner L. Autistic Disturbances
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62. Dosman CF, Drmic IE, Brian JA,
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104. Ben-Itzchak E and Zachor DA. T
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142. Tyminski RF and Moore PJ. The
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177. Aman MG, McDougle CJ, Scahill
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214. Correia CT, Almeida JP, Santos
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252. Akhondzadeh S, Tajdar H, Moham
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290. Dawson G, Rogers S, Munson J,
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Acronyms/Abbreviations ABA Applied
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Appendix A. Exact Search Strings an
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Table A2. PsycINFO search strategie
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Therapies for Children with Autism
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Therapies for Children with ASD Sys
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Appendix C. Evidence Tables Tables
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Evidence Table. Therapies for child
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Country: US Practice setting: Clini
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Dunn-Geier et al., 2000 (continued)
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Evidence Table: Therapies for Child
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Appendix D. List of Excluded Studie
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31. Aarsland D, Cummings JL and Lar
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59. Ahearn WH, Clark KM, Gardenier
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89. Allison DB, Basile VC and MacDo
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118. Ando H, Yoshimura I and Wakaba
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146. Atkinson RP, Jenson WR, Rovner
Page 619 and 620:
177. Bakare MO, Agomoh AO, Ebigbo P
Page 621 and 622:
204. Baron-Cohen S, Scott FJ, Allis
Page 623 and 624:
233. Bebko JM, Perry A and Bryson S
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262. Bergmann F, Stepp H, Metzger R
Page 627 and 628:
291. Birkan B, McClannahan LE and K
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319. Boddy F, Rowan EN, Lett D, et
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348. Bouma R and Schweitzer R. The
Page 633 and 634:
376. Broadstock M, Doughty C and Eg
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404. Brudnak MA. Application of gen
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432. Buitelaar JK. Why have drug tr
Page 639 and 640:
460. Butler DE, Nordin IC, L’Ital
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489. Campbell M, Locascio JJ, Choro
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517. Caronna EB, Augustyn M and Zuc
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546. Case-Smith J and Miller H. Occ
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574. Charlop MH, Burgio LD, Iwata B
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602. Cheng CW, Cho SH, Taylor M, et
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631. Cicero FR and Pfadt A. Investi
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662. Collier D and Reid G. A compar
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691. Coskun M, Karakoc S, Kircelli
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718. Cullen LA, Barlow JH and Cushw
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748. Davidovitch M, Holtzman G and
Page 661 and 662:
777. DeLeon IG, Fisher WW and Marhe
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805. Devlin SD, Harber MM. Collabor
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834. Doherty K, Fitzgerald M and Ma
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863. Dudley LL, Johnson C and Barne
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893. Dybvik AC. Autism and the Incl
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924. Elder JH. In-home communicatio
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953. Erickson CA, Posey DJ, Stigler
Page 675 and 676:
979. Faja S, Aylward E, Bernier R,
Page 677 and 678:
1008. Ferri R, Elia M, Agarwal N, e
Page 679 and 680:
1037. Fisher W, Kerbeshian J and Bu
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1066. Fragala-Pinkham M, Haley SM a
Page 683 and 684:
1095. Furneaux B. Keeping the balan
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1124. Garcaa-Villamisar D, Wehman P
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1152. Ghezzi PM. Discrete Trials Te
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1180. Goin-Kochel RP, Myers BJ and
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1210. Gordon R, Handleman JS and Ha
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1239. Grimaldi BL. The central role
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1268. Guptill JT, Booker AB, Gibbs
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1296. Hamdan-Allen G. Brief report:
Page 699 and 700:
1324. Hare DJ, Jones JPR and Paine
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1356. Harrison S and Berry L. Valui
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1386. Heilbrun AB, Jr., Blum N and
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1414. Hetzroni OE and Shalem U. Fro
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1443. Holburn CS. Counter the mistr
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1473. Horner RH, Carr EG, Strain PS
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1591. Johnson CR, Butter EM, Handen
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1619. Joyce PR. The medical model-w
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1647. Karmali I, Greer RD, Nuzzolo-
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1673. Kelly AB, Garnett MS, Attwood
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1702. Kielinen M, Linna SL and Moil
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1731. Klin A, Lin DJ, Gorrindo P, e
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1761. Koegel RL and Frea WD. Treatm
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1790. Kolmen BK, Feldman HM, Handen
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1819. Kratochvil CJ, Findling RL, M
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1846. Lam MK and Rao N. Developing
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1874. Lattimore LP, Parsons MB and
Page 739 and 740: 1903. Lee PC. Verification of a sim
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Page 751 and 752: 2071. MacFarlane JR and Kanaya T. W
Page 753 and 754: 2099. Malone RP, Maislin G, Choudhu
Page 755 and 756: 2127. Marin FZ. CAM versus nucleopl
Page 757 and 758: 2157. Martineau J, Roux S, Adrien J
Page 759 and 760: 2185. Matson JL and Lo Vullo SV. A
Page 761 and 762: 2213. McCabe H. The Importance of P
Page 763 and 764: 2240. McDougle CJ, Holmes JP, Carls
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Page 769 and 770: 2325. Minderaa RB, Anderson GM, Vol
Page 771 and 772: 2354. Montgomery JM, Duncan CR and
Page 773 and 774: 2385. Morrison RS, Sainato DM, Benc
Page 775 and 776: 2413. Munesue T, Ono Y, Mutoh K, et
Page 777 and 778: 2445. Napolitano DA, Tessing JL, Mc
Page 779 and 780: 2474. Niederhofer H and Pittschiele
Page 781 and 782: 2501. Nwora AJ and Gee BM. A case s
Page 783 and 784: 2530. Olive ML, Lang RB and Davis T
Page 785 and 786: 2559. Owens JA, Rosen CL and Mindel
Page 787 and 788: 2589. Pansegrouw I and Alant E. Com
Page 789: 2618. Paul C, Williams KE, Riegel K
Page 793 and 794: 2675. Piazza CC, Hagopian LP, Hughe
Page 795 and 796: 2704. Poon L, Partika N and Bolman
Page 797 and 798: 2734. Prizant BM. Speech-language p
Page 799 and 800: 2764. Rapp JT, Vollmer TR, St. Pete
Page 801 and 802: 2792. Reed P, Broomfield L, McHugh
Page 803 and 804: 2819. Remington G, Sloman L, Konsta
Page 805 and 806: 2849. Ringdahl JE, Kitsukawa K, And
Page 807 and 808: 2877. Rogers SJ. Interventions that
Page 809 and 810: 2908. Rossignol DA. Novel and emerg
Page 811 and 812: 2939. Rutter M, Kreppner J, Croft C
Page 813 and 814: 2967. Sandt D. Social Stories for S
Page 815 and 816: 2994. Scanlon K. Art therapy with a
Page 817 and 818: 3023. Schneider CK, Melmed RD, Bars
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Page 821 and 822: 3085. Shafer MS, Egel AL and Neef N
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Page 839 and 840: 3346. Tager-Flusberg H and Calkins
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3376. Taylor I, O’Reilly M and La
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3407. Thunberg G, Ahlsen E and Sand
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3435. Trembath D, Balandin S, Toghe
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3464. Turner-Brown LM, Perry TD, Di
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3492. Van Der Putt R, Dineen C, Jan
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3522. Vitiello B. Recent NIMH clini
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3553. Walenski M, Mostofsky SH, Gid
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3581. Weber RC and Thorpe J. Teachi
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3610. Wheeler JJ, Baggett BA, Fox J
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3637. Williams B. Mental handicap n
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3669. Wimpory D, Chadwick P and Nas
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3698. Worth S and Reynolds S. The A
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3728. Young JM, Krantz PJ, McClanna
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3759. Zuddas A, Di Martino A, Mugli
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Appendix F. Approach to Categorizin
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APPENDIX G. Discussion of Recent Sy
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one a casein free regime. Diets wer
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outcome data as Type 6, defined as
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Yes—no disclosures to make G7 Bai
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Table G1. Characteristics of recent
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Random assignment Appropriate compa
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Study Group design Random assignmen
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APPENDIX I. Applicability Summary T
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Social skills (continued) Domain De
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