Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Description Intervention
Author:
Lopata et al.,
2008
Country:
US
Practice
setting:
Academic
Intervention
setting:
Clinic
Enrollment
period:
NR
Funding:
NR
Author industry
relationship
disclosures:
NR
Design:
Prospective cohort
Note:
See preliminary
report of intervention,
Lopata et
al. 2006 ({#2697})
Intervention:
Manualized social
treatment program
Participants assigned to
one of two performance
feedback treatment
conditions: response-cost
or non-categorical
feedback
The response-cost group
received feedback based
on operationally defined
behaviors, and the noncategorical
feedback
group received feedback
but there were no
predetermined behavioral
categories on which
feedback was based
Each summer the program
was administered for
6 weeks, five days/week
for 6 hours each day;
there were 4 treatment
cycles each day, with
each cycle beginning with
a 20 minute structured
social skills group and
ending with a 50 minute
therapeutic activity; social
treatments were delivered
in small groups of 6
children and 3 staff
Assessments:
By treatment staff,
teachers, and parents:
WISC-IV short form,
BASC-PRS, BASC-TRS,
Skillstreaming survey,
DANVA2, Parent
Satisfaction Survey
Groups:
G1: non-categorical
G2: response-cost
Provider:
Psychology and education
graduate students
Measure of treatment
fidelity reported:
Inclusion/ Exclusion
Criteria/ Population
Inclusion criteria:
• Formal written diagnosis
of AD, autism, or PDD-
NOS by a licensed
psychologist or
psychiatrist
• WISC-IV short-form IQ
composite > 70
• Index score ≥ 80 on at
least one factor of the
WISC-IV
• Absence of a current
significant language
delay
Exclusion criteria:
• Current significant
language delay
Age, years ± SD:
G1: 9.41 ± 2.31
G2: 9.6 ± 2.12
Mental age:
Short-form IQ (WISC-IV),
mean ± SD:
G1: 97.56 ± 13.62
G2: 100.87± 17.92
Gender, n (%):
Male:
G1: 27 (93.1)
G2: 23 (92)
Female:
G1: 2 (6.9)
G2: 2 (8.0)
Race/ethnicity, n (%):
White:
G1: 26 (89.7)
G2: 22 (88)
African American:
G1: 1 (2.4)
G2: 0
Latino:
G1: 1 (1.9)
G2: 1 (4)
Other:
G1: 2 (6.9)
G2: 2 (8)
SES:
Parent education, years ±
SD:
G1: 15.83 ± 2.26
C-151
Baseline
Measures Outcomes
months ± SD:†
G1: 47.37 ± 13.77
G2: 42.82 ± 14.08
G3: 35.87 ± 13.00
Harms:
NR
Modifiers:
NR
Social Skills:
BASC social skills
score, parent rated,
mean ± SD:
G1: 36.18 ± 7.00
(n=28)
G2: 36.91 ± 8.81
(n=22)
BASC social skills
score, teacher rated,
mean ± SD:
G1: 47.38 ± 6.80
(n=28)
G2: 43.52 ± 8.57
Adaptive behavior:
BASC adaptive skills
score, parent rated,
mean ± SD:
G1: 34.29 ± 7.17
(n=28)
G2: 35.27 ± 8.69
(n=22)
BASC adaptive skills
score, teacher rated,
mean ± SD:
G1: 42.63 ± 6.53
(n=28)
G2: 41.60 ± 6.92
BSI score, parent
rated, mean ± SD:
G1: 65.86 ± 11.50
(n=28)
G2: 60.91 ± 10.88
(n=22)
BSI score, teacher
rated, mean ± SD:
G1: 53.41 ± 9.33
(n=28)
G2: 53.56 ± 7.70
Skillstreaming survey
score, parent report,
mean ± SD:
G1: 104.28 ± 22.84
(n=25)
G2: 103.15 ± 19.98
(n=20)
Skillstreaming survey
score, staff report,
mean ± SD:
Social Skills:
BASC social skills
score, parent rated,
mean ± SD:
G1: 40.75 ± 8.37
(n=28; d=-0.59)
G2: 38.59 ± 7.71
G1+G2/BL: P =
0.002
G1/G2: P = 0.153
BASC social skills
score, teacher rated,
mean ± SD:
G1: 47.84 ± 6.25
(n=28; d=-0.07)
G2: 46.76 ± 7.97
(d=-0.39)
G1+G2/BL: P =
0.008
G1/G2: P = 0.067
Adaptive behavior:
BASC adaptive
skills score, parent
rated, mean ± SD:
G1: 37.79 ± 8.01
(n=28; d=0.45)
G2: 36.05 ± 7.13
(n=22; d=0.1)
G1+G2/BL: P =
0.011
G1/G2: P = 0.133
BASC adaptive
skills score, teacher
rated, mean ± SD:
G1: 43.79 ± 5.89
(n=28; d=0.19)
G2: 44.20 ± 5.98
(d=0.4)
G1+G2/BL: P =
0.004
G1/G2: P = 0.291
BSI score, parent
rated, mean ± SD:
G1: 61.32 ± 9.78
(n=28; d=0.43)
G2: 58.55 ± 11.71
(d=0.21)
G1+G2/BL: P =
0.001