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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD (continued)<br />

Study<br />

Description Intervention<br />

Inclusion/ Exclusion<br />

Criteria/ Population<br />

Comments: *In the outcomes column, d is the Cohen’s d effect size estimate <strong>for</strong> mean differences.<br />

Author:<br />

Ludlow et al.,<br />

2008<br />

Country:<br />

UK<br />

Practice<br />

setting:<br />

Academic<br />

Intervention<br />

setting:<br />

School<br />

Enrollment<br />

period:<br />

NR<br />

Funding:<br />

Intervention:<br />

Three experiments to<br />

assess therapeutic<br />

benefits of colored<br />

overlays; participants<br />

selected the best color<br />

and side (matt or gloss)<br />

<strong>for</strong> clarity over text and as<br />

favorite over a blank<br />

sheet of paper<br />

Experiment 1 tested the<br />

rate of reading with and<br />

without colored overlays.<br />

Experiment 2 compared<br />

the rate of reading with<br />

Inclusion criteria:<br />

• Diagnosis of ASD<br />

• Recruited from schools<br />

<strong>for</strong> children with<br />

moderate learning<br />

difficulties with autism<br />

units<br />

Exclusion criteria:<br />

• See inclusion criteria<br />

Age, years ± SD (range):<br />

G1: 12.3 ± 2.1 (9-15.83)<br />

G2: 14.8 ± 8.1 (14.1-15.83)<br />

G3: 12.3 ± 2.2 (9-15.83)<br />

Mental age:<br />

IQ score (Raven’s<br />

C-153<br />

Baseline<br />

Measures Outcomes<br />

(n=28; d=0.26)<br />

G2: 62.50 ± 9.03<br />

(n=22; d=0.31)<br />

G1+G2/BL: P =<br />

0.004<br />

G1/G2: P = 0.887<br />

BASC withdrawal<br />

score, teacher rated,<br />

mean ± SD:<br />

G1: 55.46 ± 10.11<br />

(n=28; d=0.04)<br />

G2: 56.56 ± 9.44<br />

(d=0.41)<br />

G1+G2/BL: P =<br />

0.036<br />

G1/G2: P = 0.028<br />

Communication/<br />

language:<br />

DANVA2 score,<br />

mean ± SD:<br />

Child faces:<br />

G1: 87.11 ± 22.37<br />

(n=18; d=-0.17)<br />

G2: 89.22 ± 15.16<br />

(n=18; d=-0.21)<br />

G1+G2/BL: P =<br />

0.07<br />

G1/G2: P = 0.963<br />

Adult faces:<br />

G1: 101.39 ± 15.55<br />

(n=18; d=-0.06)<br />

G2: 94.06 ± 13.86<br />

(n=18; d=-0.25)<br />

G1+G2/BL: P =<br />

0.166<br />

G1/G2: P = 0.521<br />

Harms:<br />

NR<br />

Modifiers:<br />

See above<br />

Communication<br />

/language:<br />

BPVS score,<br />

mean ± SD:<br />

G1: 64.5 ± 11.2<br />

G2: 59.6 ± 5.3<br />

G3: NR<br />

Communication/<br />

language:<br />

Experiment 1:<br />

Symptoms of visual<br />

stress, mean ± SD:<br />

G1a: 0.06 ± 0.24<br />

G1c: 0.39 ± 0.78<br />

G1a/G1c: P < 0.05<br />

Words read per<br />

minute, mean ± SD:<br />

G1a: 96.9 ± 33.7<br />

G1c: 83.2 ± 32.3<br />

G1a/G1c: P < 0.001<br />

Experiment 2:<br />

Words read per

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