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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD (continued)<br />

Study<br />

Inclusion/ Exclusion<br />

Description Intervention<br />

Criteria/ Population<br />

G3: 13 G1: 2.83 ± 0.6<br />

G2: 3.1 ± 0.6<br />

G3: 3.1 ± 1.0<br />

Author:<br />

Whalen et al.,<br />

2010<br />

Country:<br />

US (CA)<br />

Practice<br />

setting:<br />

Specialized school<br />

program<br />

Intervention<br />

setting:<br />

Classroom<br />

Enrollment<br />

period:<br />

NR<br />

Funding:<br />

Agency/NR<br />

Design: RCT<br />

(randomized by<br />

classroom, no<br />

individual<br />

randomization)<br />

Intervention:<br />

TeachTown: Basics is a<br />

computer-assisted<br />

intervention (CAI) with<br />

supplementary offcomputer<br />

activities. This<br />

intervention was<br />

implemented <strong>for</strong> 3 months<br />

and consisted of 20<br />

minutes/day on the<br />

computer and 20<br />

minutes/day in<br />

supplementary activities.<br />

8 classrooms in 4 schools<br />

were randomly assigned<br />

to standard teaching or to<br />

TeachTown: Basics .<br />

Groups:<br />

G1a: TeachTown: Basics<br />

Preschool, school 1<br />

G1b: TeachTown: Basics<br />

K-1, school 1<br />

G1c: TeachTown: Basics<br />

Preschool, school 2<br />

G1d: TeachTown: Basics<br />

K-1, school 2<br />

G2a: Control, Preschool,<br />

school 3<br />

G2b: Control, K-1, school<br />

3G2c: Control, Preschool,<br />

school 4<br />

G2d: Control, K-1, school<br />

4<br />

Provider:<br />

• Teacher<br />

Treatment manual<br />

followed:<br />

No<br />

Family tutors, mean n ±<br />

SD:<br />

G1: 0.50 ± 0.9<br />

G2: 0<br />

G3: 0.6 ± 0.8<br />

Service providers, n<br />

G1: 5<br />

G2: 2<br />

G3: 1<br />

Inclusion criteria:<br />

• <strong>Children</strong> aged 3-6 years<br />

with autism<br />

• Attended Los Angeles<br />

Unified School District’s<br />

Intensive<br />

Comprehensive <strong>Autism</strong><br />

Program (ICAP)<br />

Exclusion criteria:<br />

See inclusion criteria<br />

Age, in years (range):<br />

3-6<br />

Mental age: NR<br />

Gender: NR<br />

Race/ethnicity: NR<br />

SES:<br />

Maternal education: NR<br />

Household income: NR<br />

Diagnostic approach:<br />

NR<br />

Diagnostic tool/method:<br />

Diagnostic method NR;<br />

CARS administered by<br />

each child’s teacher <strong>for</strong><br />

measurement of disease<br />

severity<br />

Diagnostic category, n<br />

(%):<br />

<strong>Autism</strong>: 47 (100)<br />

Other characteristics:<br />

NR<br />

C-26<br />

Baseline<br />

Measures Outcomes<br />

hrs/week, r 2 =<br />

0.10)<br />

G3: Negative<br />

(gains = 18.1-<br />

0.50, r 2 = 0.21)<br />

CARS score,<br />

mean:<br />

G1: 42<br />

G1a: 33<br />

G1b: 39<br />

G1c: 44<br />

G1d: 52<br />

G2: 43<br />

G2a: 45<br />

G2b: 37<br />

G2c: 45<br />

G2d: 45<br />

Peabody Picture<br />

Vocabulary Test<br />

(PPVT), mean:<br />

G1a+c: 8.82<br />

G2a+c: 9.67<br />

Communication/<br />

language:<br />

PPVT, mean:<br />

G1a+c: 23.36<br />

G2a+c: 14.92<br />

P = 0.036<br />

G1b+d vs. G2b+d<br />

(values NR): P =<br />

0.577<br />

EVT: (values NR)<br />

G1a+c vs. G2a+c:<br />

P = 0.444<br />

G1b+d vs. G2b+d:<br />

P = 0.375<br />

Brigance<br />

Inventory of Early<br />

Development<br />

(values NR)<br />

scores and<br />

subscores: no<br />

significant<br />

differences<br />

between G1 and<br />

G2<br />

Significant<br />

correlation<br />

between number<br />

of lessons<br />

mastered in G1<br />

with overall prepost<br />

change in<br />

Brigance score (P<br />

= 0.042)<br />

Harms<br />

NR

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