Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD
Study
Inclusion/Exclusion Baseline
Description Intervention
Criteria/Population Measures Outcomes
Author:
Intervention:
Inclusion criteria: Problem behavior: Problem
Sofronoff et al., Cognitive Behavior • Primary diagnosis of Children’s Inventory behavior:
2007
Therapy for Anger Asperger syndrome from of Anger score, Children’s
Country: Management, sessions a pediatrician and inter- mean:
Inventory of Anger
Australia included exploration of view with parents based Total:
score, mean:
Practice different feelings,
on DSM-IV criteria and G1: 108.7
Total:
setting:
methods for “fixing” the CAST
G2: 109.1
Post-treatment:
Academic feelings, relaxation tech- Exclusion criteria: Frustration: G1: 100.7
Intervention
setting:
niques, recruiting help to
restore positive feelings,
• See inclusion criteria
Age, years ± SD (range):
G1: 28.6
G2: 28.9
G2: 108.1
G1/BL: P <
Clinic
and social stories; 2 hours G1: 10.79 ± 1.12 (9.8-13.6) Physical aggression: 0.0001
Enrollment per week for 6 weeks G2: 10.77 ± 0.87 (10.1- G1: 25.1
G2/BL: P = NS
period:
NR
Assessments:
Therapists assessed
13.0)
Mental age:
G2: 24.1
Peer relationships:
6 week follow-up:
G1: 97.4
Funding: children individually with
Apex Autism Trust WISC; child completed
Foundation anger measures (Dylan,
IQ (WISC-III), mean ± SD G1: 23.8
(range):
G2: 24.4
G1: 105.24 ± 22.3 (95-132) Authority
G2: 108.1
G1/BL: P < 0.001
G2/BL: P = NS
Author industry What makes me angry); G2: 108.7 ± 21.6 (101-127) relationships: Frustration:
relationship parents completed Gender, n (%):
G1: 29
Post-treatment:
disclosures:
NR
Children’s Inventory of
Anger
Male:
G1: 23 (96)
G2: 28
G1: 26.1
Parent monitoring of G2: 28.4
Design: Groups:
G2: 20 (95)
instances of anger, G1/BL: P <
RCT
G1: intervention
G2: waitlist control
Female:
G1: 1 (4)
mean ± SD:
G1: 8.7 ± 4.4
0.0001
G2/BL: P = NS
Provider:
G2: 1 (5)
G2: 7.6 ± 4.3 6 week follow-up:
Postgraduate students Race/ethnicity:
Parent monitoring of G1: 24.7
from clinical psychology
program trained in the
NR
SES:
anger management, G2: 28.4
mean ± SD:* G1/BL: P <
technique in a one-day
workshop
Measure of treatment
Maternal education: NR
Household income: NR
Diagnostic approach:
Parent confidence:
G1: 4.3 ± 2.2
G2: 4.9 ± 2
0.0001
G2/BL: P = NS
Physical
fidelity reported:
Yes
Co-interventions held
Referral and in-study
confirmation
Diagnostic tool/method:
Child confidence:
G1: 2.7 ± 1.7
G2: 2.9 ± 2
aggression:
Post-treatment:
G1: 25.2
stable during treatment: Semi-structured interview
NR
and CAST based on DSM-
Concomitant therapies: IV criteria
G2: 23.0
G1/BL: P = NS
G2/BL: P = NS
NR
Diagnostic category, n
6 week follow-up:
N at enrollment: (%):
G1: 25.4
G1: 24
G2: 21
Asperger’s: 45 (100)
Other characteristics, n
G2: 28.6
G1/BL: P = NS
N at follow-up:
(%):
G2/BL: P = NS
G1: 24
G2: 21
ADHD diagnosis:
G1: 11 (46)
Peer relationships:
G2: 9 (43)
Post-treatment:
G1: 22.3
G2: 23.4
G1/BL: P < 0.05
G2/BL: P = NS
C-252