Therapies for Children With Autism Spectrum Disorders

Evidence Table. Therapies for children with ASD (continued)
Study
Inclusion/ Exclusion Baseline
Description Intervention
Criteria/ Population Measures Outcomes
intervention, and the last Diagnostic approach: G1: 7.0 ± 1.7 G1: 2.3 ± 1.7
night of the intervention. In Study
G2: 7.2 ± 3.2 G2: 4.8 ± 2.1
Children and parents Diagnostic tool/method: SSRS score, follow- (n=29)
completed assessment ADOS-G and ADI-R; up group, mean ± G1/G2: P <
measures in the presence High Functioning ASSQ SD:
0.0001
of the research team, Diagnostic category, n: Assertion:
Quality of Play
while teachers were Autism: 68
G1: 9.7 ± 2.8 Questionnaire
mailed assessment PDD-NOS: 0
Self control: score, follow-up
measures at each of the Aspergers: 0
G1: 9.8 ± 3.5 group, mean ±
testing periods.
Other characteristics, n Externalizing: SD:
Child outcome measures: (%):
G1: 4.5 ± 2.4 Post-treatment:
Loneliness Scale, PHS; Completely mainstreamed: Internalizing: Host:
parent measures: Quality 61 (89.7)
G1: 7.1 ± 1.6 G1: 4.0 ± 1.6
of Play Questionnaire, Special education classes PEI score, mean ± Guest:
SSRS; teacher measures: (but included in a main- SD:
G1: 1.8 ± 2.6
PEI; at baseline, WISC-III; streamed recess and Withdrawal: Conflict:
VABS survey form; mainstream classroom for G1: 4.0 ± 2.1 (n=31) G1: 1.8 ± 3.0
Socioeconomic Status part of the school day): 6 G2: 3.8 ± 2.1 (n=28) Engage:
Groups:
(8.8)
Aggression: G1: 4.5 ± 2.2
G1: children’s friendship Mainstream classroom with G1: 1.3 ± 1.7 (n=31) Disengage:
training intervention special help for 1-2 hours a G2: 1.4 ± 1.8 (n=28) G1: 2.1 ± 1.6
G2: children’s friendship day: 1 (1.5)
PEI score, follow-up 12 weeks:
training after 12 weeks; Grade, mean ± SD: group, mean ± SD: Host:
delayed treatment control G1: 3.2 ± 1.0
Withdrawal: G1: 3.1 ± 2.9
Provider:
G2: 3.4 ± 1.2
G1: 4.2 ± 2.2 G1/BL: P = NS
• Psychologist
Aggression: G1/PT: P < 0.05
• L.C.S.W.
G1: 1.5 ± 1.8 Guest:
• Undergraduate
High functioning G1: 1.9 ± 1.5
psychology students
ASSQ, mean ± SD: G1/BL: P = NS
Measure of treatment
G1: 22.4 ± 7.3 G1/PT: P = NS
fidelity reported:
G2: 22.0 ± 9.3 Conflict:
Yes
G1: 2.0 ± 2.6
Co-interventions held
G1/BL: P = NS
stable during treatment:
G1/PT: P <
NR
Concomitant therapies:
NR
0.0005
Frankel et al., N at enrollment:*
VABS score, mean Engage:
2010
G1: 35
± SD:
G1: 4.2 ± 2.0
(continued) G2: 33
Communication: G1/BL: P = NS
N at follow-up:
G1: 84.3 ± 20.5 G1/PT: P = NS
G1: 26
(n=34)
G2: 31
G2: 79.8 ± 15.3 Disengage:
Daily living: G1: 4.1 ± 2.2
G1: 67.0 ± 18.2 G1/BL: P <
(n=34)
0.0001
G2: 62.4 ± 15.7 G1/PT: P <
Socialization: 0.025SSRS
G1: 66.3 ± 10.8 score, mean ±
(n=34)
SD:
G2: 66.1 ± 10.8 Assertion:
Composite: G1: 11.8 ± 3.2
G1: 68.1 ± 16.4 G2: 10.5 ± 3.2
(n=34)
G1/G2: P = 0.054
G2: 64.4 ± 11.0 Self-control :
G1: 12.2 ± 2.9
G2: 10.1 ± 3.7
C-7