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Therapies for Children With Autism Spectrum Disorders

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Evidence Table. <strong>Therapies</strong> <strong>for</strong> children with ASD (continued)<br />

Study<br />

Inclusion/ Exclusion Baseline<br />

Description Intervention<br />

Criteria/ Population Measures Outcomes<br />

Practice psychoeducational PEP-R<br />

G3: 46.4 ± 21.9 G2: 69.54 ± 22.54<br />

setting:<br />

training vs. inclusive • Diagnosed with autistic G1/G2/G3: P = NS G3: 49 ± 25.24<br />

Research center education in mainstream disorder and mental VABS composite G1/BL: P = 0.02<br />

Intervention schools (i.e., treatment as retardation<br />

scale, mean ± SD: G2/BL: P = 0.022<br />

setting:<br />

usual, nonspecific Exclusion criteria: G1: 100.72 ± 42.92 G3/BL: P = NS<br />

Residential, clinic, program)<br />

and/or school Duration: 3 years in<br />

• See inclusion criteria<br />

Age, years ± SD:<br />

G2: 109.69 ± 33.83<br />

G3: 94.8 ± 27.89<br />

G1/G2/G3: P =<br />

0.009<br />

Enrollment setting<br />

G1: 9.66 ± 2.31<br />

G1/G2/G3: P = NS G1/G2: P = NS<br />

period:<br />

TEACHH residential – G2: 8.66 ± 2.01<br />

Social skills: G1/G3: P = NS<br />

NR<br />

In residence education G3: 9.09 ± 2.07<br />

VABS socialization G2/G3: P = 0.001<br />

Funding: with regular intervals Mental age, months ± SD: score, mean ± SD: VABS composite<br />

NR<br />

home and no additional G1: 20.63 ± 9.52 G1: 16.1 ± 11.6 score, 3 years,<br />

Author industry school involvement G2: 23.69 ± 10.5 G2: 16.23 ± 7.45 mean ± SD:<br />

relationship TEACCH home based – G3: 20.4 ± 6.93<br />

G3: 16 ± 5.29 G1: 127.81 ±<br />

disclosures: Attended mainstream Gender, n (%):<br />

G1/G2/G3: P = NS 45.07<br />

NR<br />

classes with support<br />

Design: teacher; psycho-<br />

Prospective cohort educational training of<br />

Male: 34 (100)<br />

Female: 0<br />

Race/ethnicity:<br />

Communication/<br />

language:<br />

VABS communica-<br />

G2: 155.23 ±<br />

39.89<br />

G3: 109.6 ± 33.52<br />

study<br />

parents <strong>for</strong> 4 weeks, then NR<br />

repeated 2 week stays on SES:<br />

tion score, mean ±<br />

SD:<br />

G1/BL: P = 0.02<br />

G2/BL: P = 0.02<br />

6 month basis<br />

Assessments:<br />

CARS, LAP-R, PEP-R,<br />

Maternal education: NR<br />

Household income: NR<br />

Diagnostic approach:<br />

G1: 15.9 ± 14.9<br />

G2: 19.46 ± 11.24<br />

G3: 18.1 ± 10.48<br />

G3/BL: P = NS<br />

Composite score<br />

with motor skills:<br />

VABS<br />

Groups:<br />

G1: TEACCH in a<br />

In Study<br />

Diagnostic tool/method:<br />

DSM-IV, CARS, ADI-R<br />

G1/G2/G3: P = NS G1/G2/G3: P =<br />

Problem behavior: NS<br />

VABS maladaptive G1/G2: P = NS<br />

residential center Diagnostic category, n (%): behaviors score,<br />

G2: TEACCH parent <strong>Autism</strong>: 34 (100)<br />

mean ± SD:<br />

training<br />

PDD-NOS: 0<br />

G1: 16.18 ± 7.33<br />

G3: inclusive education in Aspergers: 0<br />

G2: 17.92 ± 6.57<br />

G1/G3: P = NS<br />

G2/G3: P = NS<br />

Composite score<br />

w/o motor skills:<br />

mainstream school (no Other characteristics: G3: 18.5 ± 7.38 G1/G2/G3: P =<br />

protocol)<br />

Provider:<br />

G1: Educators with<br />

Severe Mental Retardation G1/G2/G3: P = NS 0.038<br />

n (%): 34 (100)<br />

Adaptive behavior: G1/G2: P = NS<br />

CARS score, mean ± SD: VABS daily living G1/G3: P = NS<br />

support of the<br />

G1: 45.75 ± 5.23 score, mean ± SD: G2/G3: P = 0.01<br />

management team (a G2: 42.42 ± 2.41 G1: 33.1 ± 12.9 Social skills:<br />

psychologist, educational G3: 42.9 ± NR<br />

G2: 31.92 ± 11.62 VABS socializa-<br />

coordinator, neurologist,<br />

G3: 27.8 ± 11.14 tion score, 3<br />

and doctor specializing in<br />

G1/G2/G3: P = NS years, mean ±<br />

normal and special<br />

Motor skills: SD:<br />

education)<br />

PEP-R fine motor G1: 25.5 ± 12.2<br />

score, mean ± SD: G2: 27.46 ± 10.89<br />

G1: 8.54 ± 4.18 G3: 16 ± 6.14<br />

G2: 9.61 ± 3.69 G1/BL: P = 0.02<br />

G3: 9.3 ± 3.8 G2/BL: P = 0.018<br />

G1/G2/G3: P = NS G3/BL: P = NS<br />

Panerai et al., G2: Support teacher, ADI-R score, mean ± SD: PEP-R gross motor Total score:<br />

2009 (continued) specific generalist team Communication:<br />

score, mean ± SD: G1/G2/G3: P =<br />

(psychologist, doctor G1: 15.18 ± 2.79 G1: 11.45 ± 3.14 0.009<br />

specializing in normal and G2: 14.15 ± 2.76 G2: 13.23 ± 4.64 G1/G2: P = NS<br />

special education, G3: 13.6 ± 2.01<br />

G3: 13.4 ± 4.03 G1/G3: P = 0.017<br />

educator-coordinator, Social impairment: G1/G2/G3: P = NS G2/G3: P = 0.006<br />

educator, social worker, G1: 27.45 ± 2.8<br />

PEP-R eye-hand Interpersonal<br />

psycho-motor and speech G2: 24.92 ± 4.54 coordination score, relationships:<br />

therapists), and parent G3: 26.4 ± 2.55<br />

mean ± SD: G1/G2/G3: P =<br />

G3: Support teacher and Repetitive behavior: G1: 4.82 ± 2.89 0.017<br />

general education G1: 7.09 ± 2.43<br />

G2: 5.54 ± 3.53 G1/G2: P = NS<br />

C-78

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