07.01.2013 Views

[Abstract Title]. - Society for Neuroscience

[Abstract Title]. - Society for Neuroscience

[Abstract Title]. - Society for Neuroscience

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Authors: *M. K. VAN VUGT 1 , M. J. KAHANA 2 , A. SCHULZE-BONHAGE 3 , B. LITT 4 , A.<br />

BRANDT 3 ;<br />

1 Neurosci, 2 Psychology, Univ. Pennsylvania, Philadelphia, PA; 3 Epilepsie Zentrum, Freiburg<br />

Univ., Freiburg, Germany; 4 Hosp. of the Univ. of Pennsylvania, Philadelphia, PA<br />

<strong>Abstract</strong>: Proactive interference is an important cause of human <strong>for</strong>getting. It occurs when<br />

recently presented items interfere with memory judgements,such as in the recent negatives<br />

paradigm (Monsell, 1978). To assess how proactive interference is reflected in brain oscillations,<br />

we recorded intracranial EEG from a set of 16 patients while they were<br />

per<strong>for</strong>ming a Sternberg task. We compared the oscillatory correlates of proactive interference <strong>for</strong><br />

letters and non-verbalizable face stimuli. Neuroimaging studies have found that proactive<br />

interference correlates most reliably with BOLD activity in the left inferior prefrontal cortex.<br />

Here we show that left dorsolateral prefrontal 90--128 Hz gamma oscillations increase, and right<br />

frontal 2--4 Hz delta oscillations decrease with proactive interference <strong>for</strong> faces. For letters, right<br />

frontopolar 2--4 Hz delta oscillations also decrease with proactive interference, but 2--14 Hz<br />

theta--alpha oscillations increase with proactive interference in the hippocampus. In summary,<br />

verbalizable and non-verbalizable stimuli show oscillatory correlates of proactive interference in<br />

different brain areas.<br />

Disclosures: M.K. van Vugt, None; M.J. Kahana, None; A. Schulze-Bonhage, None; B. Litt,<br />

None; A. Brandt, None.<br />

Poster<br />

288. Working Memory: Disorders, Genes and Connectivity<br />

Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm<br />

Program#/Poster#: 288.27/RR34<br />

Topic: F.01.f. Working memory<br />

Support: Swartz Foundation (Old Field NY)<br />

NSF 0613595<br />

<strong>Title</strong>: Relations between sensory and behavioral context and EEG spectra in a working memory<br />

task<br />

Authors: *S. MAKEIG 1 , J. ONTON 2 ;<br />

1 UCSD/Inc/SCCN, La Jolla, CA; 2 Inst. <strong>for</strong> Neural Computation, UCSD, La Jolla, CA

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!