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[Abstract Title]. - Society for Neuroscience

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The new target appeared 10 cm left or right to, and 2 cm below the central target. TMS was<br />

sometimes delivered over V1, 70 or 100 ms after disappearance of the center target. When the<br />

new target appeared, subjects were instructed to reach it, and their arm positions were monitored<br />

by Optotrak system (NDI). After each trial, subjects were required to report if they saw a new<br />

target (1-4 scale) and where it was (<strong>for</strong>ced choice between left and right). Brightness of the<br />

background was adjusted, so that subjects could detect the new target in trials without TMS.<br />

Subjects reached around the center of the monitor, when new target did not appear. In addition<br />

without TMS, they could reach toward the new target, irrespective of the duration of its<br />

appearance. When TMS was delivered, they sometimes missed detecting the new target.<br />

Especially when using TMS with 100 ms delay, they occasionally made switching toward the<br />

new target, even if they did not perceive it. However with TMS of 70 ms delay, the switching<br />

movement was deteriorated in both frequency and amplitude. In trials without conscious<br />

perception of the new target, subjects‟ judgments about the position of the new target were rather<br />

accurate, and were above the chance level. We conclude that early switching movements could<br />

be induced without conscious visual experiences, though V1 could partly be involved in the<br />

movement..<br />

Disclosures: Y. Ohki, None; S. Shibuya, None; H. Sekiguchi, None; H. Kadota, None; S.<br />

Takeuchi, None; Y. Nakajima, None.<br />

Poster<br />

262. Visually-Guided Reaching II<br />

Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm<br />

Program#/Poster#: 262.17/CC31<br />

Topic: D.05.d. Visually guided reaching<br />

Support: CIHR Grant 74634<br />

<strong>Title</strong>: Gaze-biased misreaching in optic ataxia does not generalize to other spatial planes<br />

Authors: *J. A. GRANEK 1 , L. PISELLA 2 , A. BLANGERO 2 , Y. ROSSETTI 2 , L. E. SERGIO 1 ;<br />

1 Kinesiol & Hlth. Sci., York Univ., Toronto, ON, Canada; 2 Inserm U864, Lyon, France<br />

<strong>Abstract</strong>: In our everyday movements, we typically interact directly with the object that we are<br />

viewing. Hence, the visual stimulus guiding the action is itself the target of the action. Such<br />

behaviour can be considered “standard”, or “direct”. However, the evolution of the capacity <strong>for</strong><br />

tool-use in primates has resulted in situations where the correspondence between vision and<br />

action is not direct. Rather, the mapping between stimulus and response must be learned and<br />

calibrated. This situation has been referred to as “non-standard” sensorimotor mapping. In non-

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