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[Abstract Title]. - Society for Neuroscience

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load or task switching, suggesting that the deficits may lie in the „executive‟ process of both<br />

cognitive areas. Thus, the problems related to working memory and switching in substance<br />

dependent individuals may arise when a strategy should be efficiently implemented in order to<br />

per<strong>for</strong>m the operation. Finally, women addicted to either cocaine or methamphetamine<br />

per<strong>for</strong>med significantly worse on the IGT than men addicted to the same drug types. This novel<br />

finding regarding sex-related differences raises the possibility that the frontal lobes and related<br />

decision-making abilities, are affected differently in men and women addicted to cocaine and<br />

methamphetamine. These results further elucidate the effects of different types of substance<br />

abuse and sex on separate domains of executive functioning.<br />

Disclosures: E.A.A. Van der Plas, None; E.A. Crone, None; W. van den Wildenberg,<br />

None; D. Tranel, None; A. Bechara, None.<br />

Poster<br />

289. Human Decision Making<br />

Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm<br />

Program#/Poster#: 289.14/RR50<br />

Topic: F.01.g. Decision making and reasoning<br />

Support: NIH Grant EY08266<br />

<strong>Title</strong>: The neural correlates of value and probability in decision under risk and in an equivalent<br />

motor task<br />

Authors: *S.-W. WU 1 , M. R. DELGADO 3 , L. T. MALONEY 2 ;<br />

1 Psychology, 2 Psychology and Ctr. <strong>for</strong> Neural Sci., New York Univ., New York, NY;<br />

3 Psychology, Rutgers Univ., Newark, NJ<br />

<strong>Abstract</strong>: There is considerable evidence that human economic decision-making deviates from<br />

the predictions of Expected Utility Theory (EUT) and considerable evidence from research on<br />

perception and action, indicating that human per<strong>for</strong>mance is close to optimal. This discrepancy<br />

might suggest that humans are better at making perceptual and motor decisions than economic<br />

decisions. However, given the large differences in task design between classical economic and<br />

perceptual/motor paradigms, no conclusion can be drawn. The goals of this study were to (1)<br />

develop a novel method to translate classical economic tasks to mathematically equivalent<br />

visuomotor tasks to allow comparison of choice behavior in the two modalities, and (2)<br />

investigate the neural correlates of value and probability in an economic decision task and an<br />

equivalent motor task.<br />

The experiment consisted of 3 sessions. First, subjects (N=14) participated in a motor training

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