[Abstract Title]. - Society for Neuroscience

Disclosures: S. Kodama, The Ministry of Education, Culture, Sports, Science and Technology
of Japan, B. Research Grant (principal investigator, collaborator or consultant and pending grants
as well as grants already received); S. Watanabe, The Ministry of Education, Culture, Sports,
Science and Technology of Japan, B. Research Grant (principal investigator, collaborator or
consultant and pending grants as well as grants already received); T. Suzuki, The Ministry of
Education, Culture, Sports, Science and Technology of Japan, B. Research Grant (principal
investigator, collaborator or consultant and pending grants as well as grants already received); T.
Izumi, The Ministry of Education, Culture, Sports, Science and Technology of Japan, B.
Research Grant (principal investigator, collaborator or consultant and pending grants as well as
grants already received); H. Baba , The Ministry of Education, Culture, Sports, Science and
Technology of Japan, B. Research Grant (principal investigator, collaborator or consultant and
pending grants as well as grants already received); M. Inoue, The Ministry of Education,
Culture, Sports, Science and Technology of Japan, B. Research Grant (principal investigator,
collaborator or consultant and pending grants as well as grants already received); H. Miyakawa,
The Ministry of Education, Culture, Sports, Science and Technology of Japan, B. Research Grant
(principal investigator, collaborator or consultant and pending grants as well as grants already
received).
Poster
237. Synaptic Integration II
Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm
Program#/Poster#: 237.7/D32
Topic: B.07.c. Synaptic integration
Support: Dept of Biology, Univ of KY, G. Ribble fellowship to MD
Title: Roles of the sodium calcium exchanger (NCX), the plasma membrane Ca2+-ATPase
(PMCA) and the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA) in synaptic
transmission at the crayfish and Drosophila neuromuscular junctions
Authors: *M. S. DESAI, R. L. COOPER;
Dept Biol, Univ. Kentucky, Lexington, KY
Abstract: It has been previously shown that in crayfish as well as in Drosophila, short-term
facilitation (STF) can be induced by repetitively stimulating the neuromuscular junction (NMJ).
The basis of this STF has been shown to be the buildup of residual Ca2+ in the nerve terminal.
This build up can be modified by modulating the activity of the different Ca2+ -ion channels like
the NCX, the PMCA and the SERCA and thereby the amount of STF can also be changed. Here
we have made an attempt to study the roles of these three ion channels in the regulation of