[Abstract Title]. - Society for Neuroscience

neural responses in the temporal lobe. Awake macaques were presented with a set of objects or
faces while we recorded simultaneously from neurons in the upper-bank of the superior temporal
sulcus (STS) and in the auditory cortex. Responses during three categories of saccades were
evaluated: 1) those occurring prior to fixation onset (spontaneous saccades), 2) those made at the
time of central cue fixation (visually-guided saccades) and 3) saccades made during scanning of
an image (image-guided saccades). Saccade modulation was observed for all categories of
saccades, though not always in the same cells, and irrespective of a cell‟s image selectivity.
Single unit responses typically occurred during negative components of the local field potential
(LFP). Whereas broad peri-saccadic modulation was seen in both STS and auditory cortex, only
cells in STS showed precise, short-latency responses at the termination of a saccade. The results
of our study demonstrate that even those cells that respond to face and object stimuli can show
modulation to eye movements. In addition, saccade modulation is not limited to classicallydefined
image-responsive regions of the brain: broad peri-saccadic modulation was also
observed in auditory cortex. The observation that actions can influence sensory responses will be
considered within the framework of embodied cognition.
Disclosures: S. Ovaysikia, None; A.M. Bartlett, None; N.K. Logothetis, None; K.L. Hoffman
, None.
Poster
262. Visually-Guided Reaching II
Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm
Program#/Poster#: 262.1/CC15
Topic: D.05.d. Visually guided reaching
Support: NSF Graduate Fellowship to LMMM
National Eye Institute (R01 EY015679)
Whitehall Foundation (2004-08-81-APL)
NIMH Conte Center (P50-MH-077970)
Title: Neural representation of reaches to visual and proprioceptive targets in Area 5 and MIP of
the rhesus macaque
Authors: *L. M. MCGUIRE, P. N. SABES;
Dept. of Physiol., UCSF, San Francisco, CA