[Abstract Title]. - Society for Neuroscience

ackward translation by a translator who was a native speaker of the questionnaire source
language, a review of the version obtained by an expert clinician and a comprehension test
involving five healthy subjects from the country where the target language was spoken. The
process was carried out in collaboration with the questionnaire authors.
Results: Three questionnaires (MFI, MASQ and STAI) were linguistically validated in the
twelve target languages. The FIQ and BDI were validated in the eight and four missing
languages. Irrespective of the questionnaire and dimensions studied, the same issues were
encountered in their validation. i) Issues were encountered in translation in a narrow sense. For
example, the word "things" was translated as "something" and "rug" was translated as "carpet";
ii) Literal translation was possible but largely culturally irrelevant. For example, the expression
"to walk several blocks", a completely abstract idea in Europe, was translated as "to walk more
than one kilometer"; iii) Tenses needed to be reformulated or changed for idiomatic reasons. For
example, for the MFI questionnaire, the present perfect does not exist in German, and so the
present simple was used in the first version. However, as subjects had difficulty understanding
the use of present simple with adverbs such as "lately" during the comprehension test, the
imperfect was eventually used.
Conclusions: Linguistic validation carried out using a rigorous and recognized method ensures
that the concepts assessed are equivalent in twelve languages and allows their use in large scale
studies measuring quality of life in fibromyalgia patients.
Disclosures: A. Nadjar, Pierre Fabre, F. Consultant/Advisory Board; Y. Mainguy, Pierre Fabre
laboratories, A. Employment (full or part-time); M. Galissié, Pierre Fabre laboratories, A.
Employment (full or part-time); D. Allain, Pierre Fabre laboratories, A. Employment (full or
part-time); M. Le Gal, Pierre Fabre, F. Consultant/Advisory Board; L. Bardin , Pierre Fabre
laboratories, A. Employment (full or part-time).
Poster
267. Pain: Pain Models II
Time: Sunday, November 16, 2008, 1:00 pm - 5:00 pm
Program#/Poster#: 267.4/FF10
Topic: D.08.j. Pain models
Support: NIH Grant NS42150
Title: Place preference validates sustained lifting/grooming as selective indicator of rat pain after
peripheral nerve injury
Authors: *H.-E. WU, G. GEMES, T. KAWANO, V. ZOGA, Q. HOGAN;
Dept Anesthesiol, Med. Col. Wisconsin, Milwaukee, WI