TRADITIONAL POSTER - ismrm

Poster Sessions
1377. T1 Contrast of MPRAGE in Carotid Plaque Imaging
Yiu-Cho Chung 1 , Michael Jerosch-Herold 2 , Ravi T. Seethamraju 3 , Peter Libby 4 , Marcelo Di Carli 5 ,
Raymond Kwong 6
1 Siemens Medical Solutions USA, Inc., Columbus, OH, United States; 2 Radiology, Brigham and Women's Hospital, MA, United
States; 3 Siemens Medical Solutions USA, Inc., MA, United States; 4 Cardiovascular Medicine, Brigham and Women's Hospital, MA,
United States; 5 Nuclear Medicine, Brigham and Women's Hospital, MA, United States; 6 Cardiovascular Imaging, Brigham and
Women's Hospital, MA, United States
MPRAGE has excellent T1 contrast and is useful for thrombus imaging. Though blood is usually suppressed in vessel wall imaging, nonzero blood signal
may be useful in depicting blood and vessel wall. By setting TI longer than the blood null time, MPRAGE can provide good contrast between blood and
vessel wall due to their intrinsic T1 difference. In a small patient cohort, we used such approach for MPRAGE, and compared the images with T2w-SPACE.
We found that the “grey blood” MPRAGE can provide information about the plaque and lumen that was not obvious in dark blood images.
1378. Common Artifacts of Pulmonary Artery MRA and Potential Solutions
Scott K. Nagle 1,2 , Mark L. Schiebler 1 , Christopher J. Francois 1 , Thomas M. Grist 1 , Scott B. Reeder 1,3
1 Radiology, University of Wisconsin, Madison, WI, United States; 2 Radiology, Wm. S. Middleton Veterans Affairs (VA) Hospital,
Madison, WI, United States; 3 Medical Physics, University of Wisconsin, Madison, WI, United States
Contrast-enhanced MRA has been clinically accepted at our institution as a useful alternative to CTA for the diagnosis of pulmonary embolism, particularly
in young patients where radiation dose reduction is a high priority. This increasing utilization has led to the need to understand and mitigate artifacts that are
unique to MRA, increasing the diagnostic accuracy of these scans. Based upon our experience interpreting approximately 200 clinical cases, we have
identified and provided potential solutions to two common artifacts that are unique to MRA.
1379. Comparison of Non Contrast-Enhanced Balanced TFE and CE-MRA for Evaluation of Upper
Extremity Vasculature Prior to Vascular Access Creation
Arie Simon Bode 1,2 , Robrecht Nils Planken 3 , Bastiaan Versluis 1 , Joachim E. Wildberger 1,4 , Jan H.
Tordoir 2,5 , Tim Leiner 1,5
1 Radiology, Maastricht University Medical Center, Maastricht, Netherlands; 2 Surgery, Maastricht University Medical Center,
Maastricht, Netherlands; 3 Radiology, Academic Medical Center, Amsterdam, Netherlands; 4 Cardiovascular Research Institute
Maastricht, Maastricht, , Netherlands; 5 Cardiovascular Research Institute Maastricht, Maastricht, Netherlands
Knowledge of upper extremity vascular geometry prior to dialysis access creation improves clinical outcome. Purpose of the present study was to compare a
non-contrast enhanced (NCE) balanced TFE sequence with the current standard of reference, CE-MRA. In 10 healthy volunteers and 5 patients with ESRD
we obtained both NCE-bTFE and CE-MRA images. Although CE-MRA was superior for arterial depiction NCE-bTFE yielded images of diagnostic quality
in the vast majority of subjects. Furthermore, NCE-bTFE enabled visualization of significantly more venous segments compared compared to CE-MRA.
bTFE proved to be an attractive alternative for pre-operative vascular mapping prior to vascular access creation.
1380. Multicenter Intraindividual Comparison of Gadobenate Dimeglumine and Gadofosveset Trisodium for
MR Angiography of the Renal Arteries
Gunther Schneider 1 , Mieczyslaw Pasowicz 2 , Josef Vymazal 3 , Zdenek Seidl 4 , Manuela Aschauer 5 , Deniz
Bilecen 6 , Roberto Iezzi 7 , Claudio E M Ballarati 8
1 Radiology, University Hospital Hamburg, Hamburg/Saar, Germany; 2 Diagnostics and Rehabilitation, John Paul II Hospital, Krakow,
Poland; 3 Radiology, Na Homolce Hospital, Prague, Czech Republic; 4 Radiology, Lékarská Fakulta Neurologicka Klinika, Prague,
Czech Republic; 5 Medical University of Graz, Graz, Austria; 6 Radiology, University Hospital Basel, Switzerland; 7 Radiology,
Università G. D'Annunzio, Chieti, Italy; 8 Radiology, Hospital Valduce, Como, Italy
In a prospective comparison of the efficacy and safety of gadobenate dimeglumine vs the intravascular blood pool agent gadofosveset trisodium for contrastenhanced
MR angiography (CE-MRA) of the renal arteries in 38 subjects, blinded experts consistently found first-pass CE-MRA after gadobenate
dimeglumine to be superior to CE-MRA after gadofosveset in terms of sensitivity, specificity, accuracy, PPV, and NPV. Steady state images obtained
following gadofosveset administration provided no additional diagnostic benefit in this study.
1381. Diagnostic Performance of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Peripheral
MRA: Multicenter Comparison with DSA
Timothy Leiner 1 , Suzanne C. Gerretsen 2 , Thierry le Maire 2 , Stephan Miller 3 , Siegfried Thurnher 4 ,
Christoph U. Herborn 5 , Henrik J. Michaely 6 , Harald Kramer 7 , Angelo Vanzulli 8 , Josef Vymazal 9 , Martin
Wasser 10
1 Radiology, Maastricht University Hospital, Maastrict, Netherlands; 2 Radiology, Catharina Hospital, Eindhoven, Netherlands;
3 Radiology, Eberhard-Karls University, Tübingen, Germany; 4 Radiology, Hospital of St. John of God, Vienna, Austria; 5 Radiology,
University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 6 Institute of Clinical Radiology, University Hospital Mannheim,
Mannheim, Germany; 7 Radiology, Ludwig Maximilians University, Munich, Germany; 8 Hospital Niguarda Ca’ Granda, Milan, Italy;
9 Radiology, Na Homolce Hospital, Prague, Czech Republic; 10 Radiology, Leiden University Medical Center, Leiden, Netherlands
Equivalent 0.1 mmol/kg doses of gadobenate dimeglumine and gadopentetate dimeglumine were compared in terms of diagnostic performance in 397
segments from 96 patients with suspected peripheral arterial occlusive disease undergoing CE-MRA, using DSA as the reference standard. Three blinded
readers rated the diagnostic performance of gadobenate dimeglumine significantly better in terms of sensitivity, specificity, and overall accuracy. In addition,
significantly higher PPV and NPV values were noted after gadobenate dimeglumine compared to gadopentetate dimeglumine, despite the equivalent dose.